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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIML1
Full Name:
Probable E3 ubiquitin-protein ligase TRIML1
Alias:
RING finger protein 209;Tripartite motif family-like protein 1
Type:
Mass (Da):
53002
Number AA:
468
UniProt ID:
Q8N9V2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
D
Y
F
S
S
P
V
T
T
E
C
G
H
S
F
Site 2
T29
Y
F
S
S
P
V
T
T
E
C
G
H
S
F
C
Site 3
T49
R
S
W
E
E
H
N
T
P
L
S
C
P
E
C
Site 4
S76
E
R
L
G
R
L
A
S
I
A
R
Q
L
R
S
Site 5
S83
S
I
A
R
Q
L
R
S
Q
V
L
Q
S
E
D
Site 6
S88
L
R
S
Q
V
L
Q
S
E
D
E
Q
G
S
Y
Site 7
Y95
S
E
D
E
Q
G
S
Y
G
R
M
P
T
T
A
Site 8
T100
G
S
Y
G
R
M
P
T
T
A
K
A
L
S
D
Site 9
T101
S
Y
G
R
M
P
T
T
A
K
A
L
S
D
D
Site 10
S106
P
T
T
A
K
A
L
S
D
D
E
Q
G
G
S
Site 11
S113
S
D
D
E
Q
G
G
S
A
F
V
A
Q
S
H
Site 12
S128
G
A
N
R
V
H
L
S
S
E
A
E
E
H
H
Site 13
S129
A
N
R
V
H
L
S
S
E
A
E
E
H
H
R
Site 14
T173
L
C
Q
E
E
T
K
T
C
K
Q
V
V
V
S
Site 15
Y182
K
Q
V
V
V
S
E
Y
M
K
M
H
Q
F
L
Site 16
T219
R
N
N
E
I
K
L
T
Q
Q
I
R
S
L
S
Site 17
S224
K
L
T
Q
Q
I
R
S
L
S
K
M
I
A
Q
Site 18
S226
T
Q
Q
I
R
S
L
S
K
M
I
A
Q
I
E
Site 19
S234
K
M
I
A
Q
I
E
S
S
S
Q
S
S
A
F
Site 20
S235
M
I
A
Q
I
E
S
S
S
Q
S
S
A
F
E
Site 21
S236
I
A
Q
I
E
S
S
S
Q
S
S
A
F
E
S
Site 22
S238
Q
I
E
S
S
S
Q
S
S
A
F
E
S
L
E
Site 23
S239
I
E
S
S
S
Q
S
S
A
F
E
S
L
E
E
Site 24
S243
S
Q
S
S
A
F
E
S
L
E
E
V
R
G
A
Site 25
T267
Q
C
P
E
A
T
T
T
E
L
S
L
C
R
I
Site 26
T275
E
L
S
L
C
R
I
T
G
M
K
E
M
L
R
Site 27
S285
K
E
M
L
R
K
F
S
T
E
I
T
L
D
P
Site 28
T289
R
K
F
S
T
E
I
T
L
D
P
A
T
A
N
Site 29
S307
V
L
S
E
D
L
K
S
V
K
Y
G
G
S
R
Site 30
Y310
E
D
L
K
S
V
K
Y
G
G
S
R
Q
Q
L
Site 31
S327
N
P
E
R
F
D
Q
S
A
T
V
L
G
T
Q
Site 32
T329
E
R
F
D
Q
S
A
T
V
L
G
T
Q
I
F
Site 33
Y342
I
F
T
S
G
R
H
Y
W
E
V
E
V
G
N
Site 34
T351
E
V
E
V
G
N
K
T
E
W
E
V
G
I
C
Site 35
S361
E
V
G
I
C
K
D
S
V
S
R
K
G
N
L
Site 36
S363
G
I
C
K
D
S
V
S
R
K
G
N
L
P
K
Site 37
Y387
G
L
K
I
G
D
D
Y
S
L
W
V
S
S
P
Site 38
S388
L
K
I
G
D
D
Y
S
L
W
V
S
S
P
L
Site 39
S392
D
D
Y
S
L
W
V
S
S
P
L
K
G
Q
H
Site 40
S393
D
Y
S
L
W
V
S
S
P
L
K
G
Q
H
V
Site 41
Y421
E
S
G
H
I
A
F
Y
N
G
T
D
E
S
L
Site 42
S427
F
Y
N
G
T
D
E
S
L
I
Y
S
F
P
Q
Site 43
Y430
G
T
D
E
S
L
I
Y
S
F
P
Q
A
S
F
Site 44
S431
T
D
E
S
L
I
Y
S
F
P
Q
A
S
F
Q
Site 45
S436
I
Y
S
F
P
Q
A
S
F
Q
E
A
L
R
P
Site 46
S446
E
A
L
R
P
I
F
S
P
C
L
P
N
E
G
Site 47
T456
L
P
N
E
G
T
N
T
D
P
L
T
I
C
S
Site 48
T460
G
T
N
T
D
P
L
T
I
C
S
L
N
S
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation