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Updated November 2019
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Protein Info
Short Name:
LOC375337
Full Name:
Uncharacterized protein C3orf77
Alias:
chromosome 3 open reading frame 77; flj36157; loc375337; yc009
Type:
Mass (Da):
191010
Number AA:
UniProt ID:
Q8N9V7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
R
P
P
P
L
G
P
T
T
A
S
G
P
E
G
Site 2
T11
P
P
P
L
G
P
T
T
A
S
G
P
E
G
N
Site 3
T57
R
R
M
V
A
R
A
T
P
G
R
G
E
V
E
Site 4
S65
P
G
R
G
E
V
E
S
D
K
S
V
A
A
S
Site 5
S68
G
E
V
E
S
D
K
S
V
A
A
S
G
A
G
Site 6
S72
S
D
K
S
V
A
A
S
G
A
G
K
A
A
R
Site 7
S90
E
G
R
R
G
Q
V
S
P
S
D
S
S
D
P
Site 8
S92
R
R
G
Q
V
S
P
S
D
S
S
D
P
R
G
Site 9
S94
G
Q
V
S
P
S
D
S
S
D
P
R
G
L
E
Site 10
S95
Q
V
S
P
S
D
S
S
D
P
R
G
L
E
A
Site 11
T116
P
L
Q
T
E
R
H
T
K
E
K
R
K
V
T
Site 12
T123
T
K
E
K
R
K
V
T
E
A
S
S
D
D
P
Site 13
S127
R
K
V
T
E
A
S
S
D
D
P
Q
P
G
L
Site 14
S141
L
D
L
V
R
K
E
S
L
T
S
S
E
S
F
Site 15
T143
L
V
R
K
E
S
L
T
S
S
E
S
F
Q
T
Site 16
S144
V
R
K
E
S
L
T
S
S
E
S
F
Q
T
V
Site 17
S145
R
K
E
S
L
T
S
S
E
S
F
Q
T
V
E
Site 18
S147
E
S
L
T
S
S
E
S
F
Q
T
V
E
C
L
Site 19
T150
T
S
S
E
S
F
Q
T
V
E
C
L
Q
S
L
Site 20
S177
I
R
N
K
K
L
K
S
L
E
N
P
P
L
K
Site 21
T191
K
I
T
E
N
E
A
T
Q
N
I
K
V
E
F
Site 22
Y203
V
E
F
Q
D
E
L
Y
K
N
T
P
K
Y
S
Site 23
T206
Q
D
E
L
Y
K
N
T
P
K
Y
S
C
N
I
Site 24
Y209
L
Y
K
N
T
P
K
Y
S
C
N
I
L
S
P
Site 25
S210
Y
K
N
T
P
K
Y
S
C
N
I
L
S
P
E
Site 26
S215
K
Y
S
C
N
I
L
S
P
E
V
E
N
N
S
Site 27
Y246
N
D
E
N
N
L
P
Y
K
P
D
G
G
C
M
Site 28
S267
S
K
K
E
N
L
R
S
L
A
E
K
S
D
T
Site 29
S272
L
R
S
L
A
E
K
S
D
T
N
S
I
P
Q
Site 30
T274
S
L
A
E
K
S
D
T
N
S
I
P
Q
L
L
Site 31
S276
A
E
K
S
D
T
N
S
I
P
Q
L
L
Q
T
Site 32
S298
N
K
L
L
P
E
E
S
D
L
Y
Q
S
K
T
Site 33
Y301
L
P
E
E
S
D
L
Y
Q
S
K
T
N
G
L
Site 34
T305
S
D
L
Y
Q
S
K
T
N
G
L
L
S
C
L
Site 35
Y319
L
Q
H
E
K
N
K
Y
S
I
E
E
S
S
V
Site 36
S320
Q
H
E
K
N
K
Y
S
I
E
E
S
S
V
G
Site 37
S324
N
K
Y
S
I
E
E
S
S
V
G
R
K
P
R
Site 38
S325
K
Y
S
I
E
E
S
S
V
G
R
K
P
R
K
Site 39
T343
L
S
E
K
A
D
E
T
V
T
E
M
N
F
S
Site 40
Y353
E
M
N
F
S
N
E
Y
N
K
S
E
L
M
L
Site 41
S356
F
S
N
E
Y
N
K
S
E
L
M
L
Q
E
N
Site 42
S376
G
K
E
A
E
T
K
S
P
L
N
V
L
R
K
Site 43
S390
K
V
S
H
N
T
V
S
L
M
D
H
L
L
S
Site 44
S397
S
L
M
D
H
L
L
S
V
P
E
T
V
E
K
Site 45
T401
H
L
L
S
V
P
E
T
V
E
K
E
T
S
S
Site 46
S407
E
T
V
E
K
E
T
S
S
E
H
H
V
N
A
Site 47
S408
T
V
E
K
E
T
S
S
E
H
H
V
N
A
V
Site 48
T428
E
P
L
L
K
E
E
T
E
N
A
S
E
P
L
Site 49
Y437
N
A
S
E
P
L
G
Y
E
S
M
A
S
K
E
Site 50
S439
S
E
P
L
G
Y
E
S
M
A
S
K
E
D
F
Site 51
S442
L
G
Y
E
S
M
A
S
K
E
D
F
K
S
M
Site 52
S448
A
S
K
E
D
F
K
S
M
K
S
F
I
G
K
Site 53
S451
E
D
F
K
S
M
K
S
F
I
G
K
S
P
N
Site 54
S456
M
K
S
F
I
G
K
S
P
N
E
Y
H
I
E
Site 55
Y460
I
G
K
S
P
N
E
Y
H
I
E
R
R
S
S
Site 56
S466
E
Y
H
I
E
R
R
S
S
R
E
D
L
R
S
Site 57
S467
Y
H
I
E
R
R
S
S
R
E
D
L
R
S
A
Site 58
S473
S
S
R
E
D
L
R
S
A
S
E
E
L
K
L
Site 59
S475
R
E
D
L
R
S
A
S
E
E
L
K
L
S
C
Site 60
S481
A
S
E
E
L
K
L
S
C
Q
R
T
I
P
M
Site 61
T485
L
K
L
S
C
Q
R
T
I
P
M
T
G
K
R
Site 62
Y496
T
G
K
R
T
W
P
Y
Y
S
C
A
R
I
S
Site 63
Y497
G
K
R
T
W
P
Y
Y
S
C
A
R
I
S
A
Site 64
S511
A
W
C
W
K
K
A
S
L
P
E
S
S
Y
F
Site 65
S515
K
K
A
S
L
P
E
S
S
Y
F
L
R
G
S
Site 66
S516
K
A
S
L
P
E
S
S
Y
F
L
R
G
S
Q
Site 67
Y517
A
S
L
P
E
S
S
Y
F
L
R
G
S
Q
E
Site 68
S522
S
S
Y
F
L
R
G
S
Q
E
S
C
R
Q
V
Site 69
S525
F
L
R
G
S
Q
E
S
C
R
Q
V
D
V
P
Site 70
T542
Q
T
N
Q
T
H
L
T
D
S
K
L
L
L
Q
Site 71
S551
S
K
L
L
L
Q
S
S
L
T
E
T
N
T
E
Site 72
T553
L
L
L
Q
S
S
L
T
E
T
N
T
E
S
S
Site 73
T555
L
Q
S
S
L
T
E
T
N
T
E
S
S
S
K
Site 74
T557
S
S
L
T
E
T
N
T
E
S
S
S
K
E
K
Site 75
S561
E
T
N
T
E
S
S
S
K
E
K
L
D
S
N
Site 76
S567
S
S
K
E
K
L
D
S
N
S
N
C
L
S
S
Site 77
S569
K
E
K
L
D
S
N
S
N
C
L
S
S
V
S
Site 78
S573
D
S
N
S
N
C
L
S
S
V
S
A
V
E
P
Site 79
S574
S
N
S
N
C
L
S
S
V
S
A
V
E
P
T
Site 80
S598
K
D
D
K
K
I
K
S
E
E
L
S
R
R
G
Site 81
S602
K
I
K
S
E
E
L
S
R
R
G
S
E
V
I
Site 82
S606
E
E
L
S
R
R
G
S
E
V
I
S
N
T
T
Site 83
S610
R
R
G
S
E
V
I
S
N
T
T
E
D
T
Q
Site 84
T616
I
S
N
T
T
E
D
T
Q
L
T
S
E
T
Q
Site 85
S620
T
E
D
T
Q
L
T
S
E
T
Q
S
L
T
G
Site 86
S624
Q
L
T
S
E
T
Q
S
L
T
G
N
K
K
K
Site 87
S654
D
G
Q
E
A
N
N
S
A
G
K
T
I
H
R
Site 88
T658
A
N
N
S
A
G
K
T
I
H
R
K
A
C
I
Site 89
S696
I
P
L
L
K
N
K
S
E
K
R
K
E
V
N
Site 90
S706
R
K
E
V
N
A
K
S
S
E
R
E
A
Y
S
Site 91
S707
K
E
V
N
A
K
S
S
E
R
E
A
Y
S
P
Site 92
Y712
K
S
S
E
R
E
A
Y
S
P
L
E
L
L
D
Site 93
S713
S
S
E
R
E
A
Y
S
P
L
E
L
L
D
N
Site 94
S722
L
E
L
L
D
N
L
S
G
A
D
V
R
Q
N
Site 95
S731
A
D
V
R
Q
N
R
S
K
E
N
V
S
M
M
Site 96
S746
M
L
G
P
Q
T
L
S
I
R
N
S
V
T
P
Site 97
S750
Q
T
L
S
I
R
N
S
V
T
P
V
Q
A
S
Site 98
T752
L
S
I
R
N
S
V
T
P
V
Q
A
S
S
D
Site 99
S758
V
T
P
V
Q
A
S
S
D
S
F
Y
N
K
K
Site 100
S760
P
V
Q
A
S
S
D
S
F
Y
N
K
K
S
Y
Site 101
Y762
Q
A
S
S
D
S
F
Y
N
K
K
S
Y
S
I
Site 102
S766
D
S
F
Y
N
K
K
S
Y
S
I
S
P
S
F
Site 103
S768
F
Y
N
K
K
S
Y
S
I
S
P
S
F
T
K
Site 104
S770
N
K
K
S
Y
S
I
S
P
S
F
T
K
Q
G
Site 105
S772
K
S
Y
S
I
S
P
S
F
T
K
Q
G
N
N
Site 106
T774
Y
S
I
S
P
S
F
T
K
Q
G
N
N
S
K
Site 107
S780
F
T
K
Q
G
N
N
S
K
P
S
N
H
V
S
Site 108
S783
Q
G
N
N
S
K
P
S
N
H
V
S
E
P
G
Site 109
S787
S
K
P
S
N
H
V
S
E
P
G
N
I
V
S
Site 110
S794
S
E
P
G
N
I
V
S
N
K
E
V
A
S
L
Site 111
S800
V
S
N
K
E
V
A
S
L
T
V
E
N
N
A
Site 112
T802
N
K
E
V
A
S
L
T
V
E
N
N
A
F
S
Site 113
Y814
A
F
S
C
D
P
G
Y
V
E
K
S
P
S
F
Site 114
S818
D
P
G
Y
V
E
K
S
P
S
F
C
C
N
E
Site 115
S820
G
Y
V
E
K
S
P
S
F
C
C
N
E
Q
E
Site 116
T828
F
C
C
N
E
Q
E
T
F
R
P
V
S
S
E
Site 117
S833
Q
E
T
F
R
P
V
S
S
E
V
R
G
R
K
Site 118
S834
E
T
F
R
P
V
S
S
E
V
R
G
R
K
I
Site 119
T842
E
V
R
G
R
K
I
T
K
N
F
S
E
V
G
Site 120
S846
R
K
I
T
K
N
F
S
E
V
G
F
P
D
I
Site 121
S877
D
P
D
L
F
G
V
S
N
E
G
E
L
S
F
Site 122
S883
V
S
N
E
G
E
L
S
F
T
S
E
V
P
K
Site 123
T885
N
E
G
E
L
S
F
T
S
E
V
P
K
I
S
Site 124
S886
E
G
E
L
S
F
T
S
E
V
P
K
I
S
Q
Site 125
S892
T
S
E
V
P
K
I
S
Q
E
P
N
V
A
G
Site 126
T904
V
A
G
E
H
Q
S
T
D
S
K
Y
M
E
T
Site 127
Y908
H
Q
S
T
D
S
K
Y
M
E
T
P
V
K
K
Site 128
T911
T
D
S
K
Y
M
E
T
P
V
K
K
E
P
S
Site 129
S939
I
K
P
D
I
C
A
S
N
S
A
E
S
E
I
Site 130
S941
P
D
I
C
A
S
N
S
A
E
S
E
I
K
R
Site 131
S965
G
E
V
A
N
E
T
S
E
N
E
T
L
G
D
Site 132
T969
N
E
T
S
E
N
E
T
L
G
D
F
S
E
Q
Site 133
S974
N
E
T
L
G
D
F
S
E
Q
I
K
G
S
D
Site 134
S980
F
S
E
Q
I
K
G
S
D
L
D
E
K
H
R
Site 135
T989
L
D
E
K
H
R
F
T
D
K
V
I
T
K
E
Site 136
Y1002
K
E
E
K
E
N
I
Y
E
V
C
K
S
K
D
Site 137
S1007
N
I
Y
E
V
C
K
S
K
D
S
R
N
A
D
Site 138
S1040
L
V
P
P
L
N
L
S
G
R
Q
E
D
T
I
Site 139
T1046
L
S
G
R
Q
E
D
T
I
L
N
T
W
M
N
Site 140
T1071
L
K
L
Q
N
P
E
T
C
E
I
F
K
R
E
Site 141
Y1152
A
V
N
I
F
M
E
Y
Y
R
K
F
P
P
G
Site 142
Y1153
V
N
I
F
M
E
Y
Y
R
K
F
P
P
G
V
Site 143
Y1161
R
K
F
P
P
G
V
Y
F
D
L
Q
V
L
N
Site 144
Y1242
L
D
P
E
H
F
N
Y
I
V
K
L
L
Y
Q
Site 145
Y1248
N
Y
I
V
K
L
L
Y
Q
V
Q
A
S
K
Q
Site 146
S1265
T
A
V
L
E
M
K
S
R
L
Q
M
R
R
F
Site 147
T1346
P
F
C
E
F
A
E
T
V
S
K
D
P
Q
N
Site 148
Y1370
R
I
G
I
S
A
M
Y
F
Y
H
K
L
L
Q
Site 149
Y1372
G
I
S
A
M
Y
F
Y
H
K
L
L
Q
W
S
Site 150
Y1389
R
K
V
L
E
K
L
Y
E
L
K
I
H
F
T
Site 151
T1443
E
S
E
W
I
I
N
T
P
L
W
P
C
D
R
Site 152
S1471
A
H
E
I
L
A
K
S
L
Y
R
Q
T
F
E
Site 153
T1476
A
K
S
L
Y
R
Q
T
F
E
V
L
Q
N
L
Site 154
S1489
N
L
P
G
F
Q
N
S
Q
E
T
V
E
V
S
Site 155
T1492
G
F
Q
N
S
Q
E
T
V
E
V
S
Q
Y
S
Site 156
S1496
S
Q
E
T
V
E
V
S
Q
Y
S
L
L
F
N
Site 157
Y1498
E
T
V
E
V
S
Q
Y
S
L
L
F
N
K
L
Site 158
S1518
E
S
S
S
L
G
M
S
S
S
V
A
E
F
M
Site 159
T1542
S
F
L
R
R
L
I
T
S
L
G
R
S
R
L
Site 160
S1543
F
L
R
R
L
I
T
S
L
G
R
S
R
L
W
Site 161
S1547
L
I
T
S
L
G
R
S
R
L
W
L
K
A
R
Site 162
Y1557
W
L
K
A
R
A
H
Y
K
S
A
L
S
L
G
Site 163
S1559
K
A
R
A
H
Y
K
S
A
L
S
L
G
C
Y
Site 164
S1603
F
M
V
S
N
A
S
S
I
Q
S
P
G
T
S
Site 165
S1606
S
N
A
S
S
I
Q
S
P
G
T
S
T
Q
I
Site 166
T1609
S
S
I
Q
S
P
G
T
S
T
Q
I
L
Q
I
Site 167
S1626
K
R
C
E
D
N
Q
S
R
S
N
D
D
Y
Q
Site 168
Y1632
Q
S
R
S
N
D
D
Y
Q
A
A
V
E
R
L
Site 169
T1656
K
L
F
V
K
H
M
T
V
N
V
N
K
E
Q
Site 170
S1666
V
N
K
E
Q
V
Y
S
L
E
H
C
S
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation