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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FSIP1
Full Name:
Fibrous sheath-interacting protein 1
Alias:
Type:
Mass (Da):
66121
Number AA:
581
UniProt ID:
Q8NA03
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
K
G
N
L
D
G
I
S
K
P
A
S
N
S
R
Site 2
S16
D
G
I
S
K
P
A
S
N
S
R
I
R
P
G
Site 3
S18
I
S
K
P
A
S
N
S
R
I
R
P
G
S
R
Site 4
S24
N
S
R
I
R
P
G
S
R
S
S
N
A
S
L
Site 5
S26
R
I
R
P
G
S
R
S
S
N
A
S
L
E
V
Site 6
S27
I
R
P
G
S
R
S
S
N
A
S
L
E
V
L
Site 7
S30
G
S
R
S
S
N
A
S
L
E
V
L
S
T
E
Site 8
S35
N
A
S
L
E
V
L
S
T
E
P
G
S
F
K
Site 9
S40
V
L
S
T
E
P
G
S
F
K
V
D
T
A
S
Site 10
T45
P
G
S
F
K
V
D
T
A
S
N
L
N
S
G
Site 11
S47
S
F
K
V
D
T
A
S
N
L
N
S
G
K
E
Site 12
S51
D
T
A
S
N
L
N
S
G
K
E
D
H
S
E
Site 13
S57
N
S
G
K
E
D
H
S
E
S
S
N
T
E
N
Site 14
S59
G
K
E
D
H
S
E
S
S
N
T
E
N
R
R
Site 15
T62
D
H
S
E
S
S
N
T
E
N
R
R
T
S
N
Site 16
T67
S
N
T
E
N
R
R
T
S
N
D
D
K
Q
E
Site 17
S68
N
T
E
N
R
R
T
S
N
D
D
K
Q
E
S
Site 18
S75
S
N
D
D
K
Q
E
S
C
S
E
K
I
K
L
Site 19
S87
I
K
L
A
E
E
G
S
D
E
D
L
D
L
V
Site 20
S103
H
Q
I
I
S
E
C
S
D
E
P
K
L
K
E
Site 21
S113
P
K
L
K
E
L
D
S
Q
L
Q
D
A
I
Q
Site 22
S156
K
L
W
E
E
I
K
S
A
K
Y
S
E
A
W
Site 23
S160
E
I
K
S
A
K
Y
S
E
A
W
Q
S
K
E
Site 24
S165
K
Y
S
E
A
W
Q
S
K
E
E
M
E
N
T
Site 25
T172
S
K
E
E
M
E
N
T
K
K
F
L
S
L
T
Site 26
S177
E
N
T
K
K
F
L
S
L
T
A
V
S
E
E
Site 27
T179
T
K
K
F
L
S
L
T
A
V
S
E
E
T
V
Site 28
T185
L
T
A
V
S
E
E
T
V
G
P
S
H
E
E
Site 29
T195
P
S
H
E
E
E
D
T
F
S
S
V
F
H
T
Site 30
S197
H
E
E
E
D
T
F
S
S
V
F
H
T
Q
I
Site 31
T202
T
F
S
S
V
F
H
T
Q
I
P
P
E
E
Y
Site 32
T221
Q
K
L
N
K
D
F
T
C
D
V
E
R
N
E
Site 33
S229
C
D
V
E
R
N
E
S
L
I
K
S
G
K
K
Site 34
S233
R
N
E
S
L
I
K
S
G
K
K
P
F
S
N
Site 35
S239
K
S
G
K
K
P
F
S
N
T
E
K
I
E
L
Site 36
S291
K
D
L
D
E
K
D
S
G
L
S
S
S
E
G
Site 37
S295
E
K
D
S
G
L
S
S
S
E
G
D
Q
S
G
Site 38
S296
K
D
S
G
L
S
S
S
E
G
D
Q
S
G
W
Site 39
S301
S
S
S
E
G
D
Q
S
G
W
V
V
P
V
K
Site 40
T315
K
G
Y
E
L
A
V
T
Q
H
Q
Q
L
A
E
Site 41
S331
D
I
K
L
Q
E
L
S
A
A
S
P
T
I
S
Site 42
T336
E
L
S
A
A
S
P
T
I
S
S
F
S
P
R
Site 43
S338
S
A
A
S
P
T
I
S
S
F
S
P
R
L
E
Site 44
S339
A
A
S
P
T
I
S
S
F
S
P
R
L
E
N
Site 45
S341
S
P
T
I
S
S
F
S
P
R
L
E
N
R
N
Site 46
T363
G
E
R
N
M
E
V
T
P
G
E
K
I
L
R
Site 47
T372
G
E
K
I
L
R
N
T
K
E
Q
R
D
L
H
Site 48
S399
M
K
E
N
V
L
E
S
T
S
C
L
S
E
E
Site 49
S421
E
C
I
L
K
Q
K
S
I
I
K
L
S
S
E
Site 50
S426
Q
K
S
I
I
K
L
S
S
E
R
K
K
E
D
Site 51
S427
K
S
I
I
K
L
S
S
E
R
K
K
E
D
I
Site 52
T438
K
E
D
I
E
D
V
T
P
V
F
P
Q
L
S
Site 53
S447
V
F
P
Q
L
S
R
S
I
I
S
K
L
L
N
Site 54
S450
Q
L
S
R
S
I
I
S
K
L
L
N
E
S
E
Site 55
S479
E
S
E
E
C
E
A
S
K
G
Y
Y
L
T
K
Site 56
Y483
C
E
A
S
K
G
Y
Y
L
T
K
A
L
T
G
Site 57
T485
A
S
K
G
Y
Y
L
T
K
A
L
T
G
H
N
Site 58
T489
Y
Y
L
T
K
A
L
T
G
H
N
M
S
E
A
Site 59
T499
N
M
S
E
A
L
V
T
E
A
E
N
M
K
C
Site 60
T518
K
D
V
I
I
S
D
T
K
D
Y
F
M
S
K
Site 61
Y521
I
I
S
D
T
K
D
Y
F
M
S
K
T
L
G
Site 62
S524
D
T
K
D
Y
F
M
S
K
T
L
G
I
G
R
Site 63
T526
K
D
Y
F
M
S
K
T
L
G
I
G
R
L
K
Site 64
S536
I
G
R
L
K
R
P
S
F
L
D
D
P
L
Y
Site 65
Y543
S
F
L
D
D
P
L
Y
G
I
S
V
S
L
S
Site 66
S546
D
D
P
L
Y
G
I
S
V
S
L
S
S
E
D
Site 67
S548
P
L
Y
G
I
S
V
S
L
S
S
E
D
Q
H
Site 68
S550
Y
G
I
S
V
S
L
S
S
E
D
Q
H
L
K
Site 69
S551
G
I
S
V
S
L
S
S
E
D
Q
H
L
K
L
Site 70
S559
E
D
Q
H
L
K
L
S
S
P
E
N
T
I
A
Site 71
S560
D
Q
H
L
K
L
S
S
P
E
N
T
I
A
D
Site 72
T564
K
L
S
S
P
E
N
T
I
A
D
E
Q
E
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation