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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATG16L2
Full Name:
Autophagy-related protein 16-2
Alias:
APG16-like 2;WD repeat-containing protein 80
Type:
Mass (Da):
68998
Number AA:
619
UniProt ID:
Q8NAA4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
Q
L
R
L
R
D
R
T
Q
K
A
L
F
L
E
Site 2
S54
A
E
L
L
D
K
F
S
K
K
L
Q
P
E
P
Site 3
S63
K
L
Q
P
E
P
N
S
V
T
P
T
T
H
Q
Site 4
T65
Q
P
E
P
N
S
V
T
P
T
T
H
Q
G
P
Site 5
T67
E
P
N
S
V
T
P
T
T
H
Q
G
P
W
E
Site 6
S76
H
Q
G
P
W
E
E
S
E
L
D
S
D
Q
V
Site 7
S80
W
E
E
S
E
L
D
S
D
Q
V
P
S
L
V
Site 8
T120
E
K
G
A
A
L
G
T
L
E
S
E
L
Q
Q
Site 9
S123
A
A
L
G
T
L
E
S
E
L
Q
Q
R
Q
S
Site 10
S130
S
E
L
Q
Q
R
Q
S
R
L
A
A
L
E
A
Site 11
Y167
N
A
V
Q
R
A
A
Y
E
A
L
R
A
H
V
Site 12
S222
R
A
K
Q
A
R
V
S
Q
E
L
K
K
A
A
Site 13
T232
L
K
K
A
A
K
R
T
V
S
I
S
E
G
P
Site 14
S234
K
A
A
K
R
T
V
S
I
S
E
G
P
D
T
Site 15
S236
A
K
R
T
V
S
I
S
E
G
P
D
T
L
G
Site 16
T241
S
I
S
E
G
P
D
T
L
G
D
G
M
R
E
Site 17
T252
G
M
R
E
R
R
E
T
L
A
L
A
P
E
P
Site 18
S276
K
W
K
R
P
F
R
S
A
S
A
T
S
L
T
Site 19
S278
K
R
P
F
R
S
A
S
A
T
S
L
T
L
S
Site 20
T280
P
F
R
S
A
S
A
T
S
L
T
L
S
H
C
Site 21
S304
F
K
K
R
R
G
H
S
I
G
G
A
P
E
Q
Site 22
T375
S
R
L
E
A
N
Q
T
L
E
G
A
G
G
S
Site 23
T384
E
G
A
G
G
S
I
T
S
V
D
F
D
P
S
Site 24
S385
G
A
G
G
S
I
T
S
V
D
F
D
P
S
G
Site 25
S414
W
K
V
G
E
A
Q
S
K
E
T
L
S
G
H
Site 26
T426
S
G
H
K
D
K
V
T
A
A
K
F
K
L
T
Site 27
T439
L
T
R
H
Q
A
V
T
G
S
R
D
R
T
V
Site 28
S441
R
H
Q
A
V
T
G
S
R
D
R
T
V
K
E
Site 29
T445
V
T
G
S
R
D
R
T
V
K
E
W
D
L
G
Site 30
Y455
E
W
D
L
G
R
A
Y
C
S
R
T
I
N
V
Site 31
T459
G
R
A
Y
C
S
R
T
I
N
V
L
S
Y
C
Site 32
T496
D
S
R
G
P
H
C
T
Q
V
I
P
V
Q
G
Site 33
T506
I
P
V
Q
G
R
V
T
S
L
S
L
S
H
D
Site 34
S507
P
V
Q
G
R
V
T
S
L
S
L
S
H
D
Q
Site 35
S509
Q
G
R
V
T
S
L
S
L
S
H
D
Q
L
H
Site 36
S511
R
V
T
S
L
S
L
S
H
D
Q
L
H
L
L
Site 37
S519
H
D
Q
L
H
L
L
S
C
S
R
D
N
T
L
Site 38
T525
L
S
C
S
R
D
N
T
L
K
V
I
D
L
R
Site 39
S534
K
V
I
D
L
R
V
S
N
I
R
Q
V
F
R
Site 40
T552
F
K
C
G
S
D
W
T
K
A
V
F
S
P
D
Site 41
S557
D
W
T
K
A
V
F
S
P
D
R
S
Y
A
L
Site 42
Y562
V
F
S
P
D
R
S
Y
A
L
A
G
S
C
D
Site 43
T579
L
Y
I
W
D
V
D
T
G
K
L
E
S
R
L
Site 44
S584
V
D
T
G
K
L
E
S
R
L
Q
G
P
H
C
Site 45
S608
Y
S
G
S
H
M
V
S
V
D
Q
G
R
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation