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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KBTBD3
Full Name:
Kelch repeat and BTB domain-containing protein 3
Alias:
BTB and kelch domain-containing protein 3
Type:
Mass (Da):
69395
Number AA:
608
UniProt ID:
Q8NAB2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
Y
A
F
N
Q
R
S
T
C
N
G
I
P
S
E
Site 2
S27
K
K
N
N
F
L
V
S
E
D
H
G
Q
K
I
Site 3
S36
D
H
G
Q
K
I
L
S
V
L
Q
N
F
R
E
Site 4
Y48
F
R
E
Q
N
V
F
Y
D
F
K
I
I
M
K
Site 5
S88
M
K
E
R
D
D
G
S
V
T
I
T
N
L
S
Site 6
T90
E
R
D
D
G
S
V
T
I
T
N
L
S
S
K
Site 7
T92
D
D
G
S
V
T
I
T
N
L
S
S
K
A
V
Site 8
Y105
A
V
K
A
F
L
D
Y
A
Y
T
G
K
T
K
Site 9
Y107
K
A
F
L
D
Y
A
Y
T
G
K
T
K
I
T
Site 10
S162
S
I
S
D
S
Y
G
S
T
S
L
F
D
H
A
Site 11
T163
I
S
D
S
Y
G
S
T
S
L
F
D
H
A
L
Site 12
S164
S
D
S
Y
G
S
T
S
L
F
D
H
A
L
H
Site 13
S178
H
F
V
Q
H
H
F
S
L
L
F
K
S
S
D
Site 14
S183
H
F
S
L
L
F
K
S
S
D
F
L
E
M
N
Site 15
Y229
N
L
E
S
R
Q
K
Y
L
P
H
L
I
E
K
Site 16
S243
K
V
R
L
H
Q
L
S
E
E
T
L
Q
D
C
Site 17
S256
D
C
L
F
N
E
E
S
L
L
K
S
T
N
C
Site 18
S260
N
E
E
S
L
L
K
S
T
N
C
F
D
I
I
Site 19
S287
L
F
P
D
A
R
P
S
T
T
E
K
Y
I
F
Site 20
T288
F
P
D
A
R
P
S
T
T
E
K
Y
I
F
I
Site 21
Y292
R
P
S
T
T
E
K
Y
I
F
I
H
K
T
E
Site 22
T298
K
Y
I
F
I
H
K
T
E
E
N
G
E
N
Q
Site 23
Y306
E
E
N
G
E
N
Q
Y
T
F
C
Y
N
I
K
Site 24
S323
S
W
K
I
L
P
Q
S
H
L
I
D
L
P
G
Site 25
S331
H
L
I
D
L
P
G
S
S
L
S
S
Y
G
E
Site 26
S332
L
I
D
L
P
G
S
S
L
S
S
Y
G
E
K
Site 27
S334
D
L
P
G
S
S
L
S
S
Y
G
E
K
I
F
Site 28
Y336
P
G
S
S
L
S
S
Y
G
E
K
I
F
L
T
Site 29
T343
Y
G
E
K
I
F
L
T
G
G
C
K
G
K
C
Site 30
S361
V
R
L
H
I
A
E
S
Y
H
D
A
T
D
Q
Site 31
S383
K
N
D
F
F
L
V
S
T
M
K
T
P
R
T
Site 32
T387
F
L
V
S
T
M
K
T
P
R
T
M
H
T
S
Site 33
T390
S
T
M
K
T
P
R
T
M
H
T
S
V
M
A
Site 34
S394
T
P
R
T
M
H
T
S
V
M
A
L
D
R
L
Site 35
S411
I
G
G
K
T
R
G
S
R
D
I
K
S
L
L
Site 36
S416
R
G
S
R
D
I
K
S
L
L
D
V
E
S
Y
Site 37
S422
K
S
L
L
D
V
E
S
Y
N
P
L
S
K
E
Site 38
Y423
S
L
L
D
V
E
S
Y
N
P
L
S
K
E
W
Site 39
S427
V
E
S
Y
N
P
L
S
K
E
W
I
S
V
S
Site 40
S432
P
L
S
K
E
W
I
S
V
S
P
L
P
R
G
Site 41
S434
S
K
E
W
I
S
V
S
P
L
P
R
G
I
Y
Site 42
Y441
S
P
L
P
R
G
I
Y
Y
P
E
A
S
T
C
Site 43
Y442
P
L
P
R
G
I
Y
Y
P
E
A
S
T
C
Q
Site 44
Y556
I
Y
I
L
G
G
D
Y
A
P
D
E
I
T
D
Site 45
T562
D
Y
A
P
D
E
I
T
D
E
V
Q
V
Y
H
Site 46
Y568
I
T
D
E
V
Q
V
Y
H
S
N
R
S
E
W
Site 47
S570
D
E
V
Q
V
Y
H
S
N
R
S
E
W
E
E
Site 48
S579
R
S
E
W
E
E
V
S
P
M
P
R
A
L
T
Site 49
Y589
P
R
A
L
T
E
F
Y
C
Q
V
I
Q
F
N
Site 50
Y598
Q
V
I
Q
F
N
K
Y
R
D
P
W
F
S
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation