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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM73A
Full Name:
Protein FAM73A
Alias:
FA73A; Family with sequence similarity 73, member A; FLJ35093; Loc374986; LOC374986
Type:
Membrane, Integral membrane protein
Mass (Da):
71006
Number AA:
632
UniProt ID:
Q8NAN2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
Q
I
R
R
G
A
M
S
E
E
T
V
S
E
S
Site 2
T37
R
G
A
M
S
E
E
T
V
S
E
S
Q
F
S
Site 3
S39
A
M
S
E
E
T
V
S
E
S
Q
F
S
L
K
Site 4
S41
S
E
E
T
V
S
E
S
Q
F
S
L
K
T
A
Site 5
S44
T
V
S
E
S
Q
F
S
L
K
T
A
A
L
R
Site 6
T58
R
V
F
D
L
P
L
T
W
Y
Y
S
L
S
Q
Site 7
Y60
F
D
L
P
L
T
W
Y
Y
S
L
S
Q
I
K
Site 8
Y61
D
L
P
L
T
W
Y
Y
S
L
S
Q
I
K
F
Site 9
S62
L
P
L
T
W
Y
Y
S
L
S
Q
I
K
F
S
Site 10
T117
E
H
L
I
L
E
Y
T
K
R
A
A
S
D
K
Site 11
S122
E
Y
T
K
R
A
A
S
D
K
G
S
S
C
S
Site 12
S126
R
A
A
S
D
K
G
S
S
C
S
S
S
R
Q
Site 13
S127
A
A
S
D
K
G
S
S
C
S
S
S
R
Q
N
Site 14
S129
S
D
K
G
S
S
C
S
S
S
R
Q
N
L
T
Site 15
S130
D
K
G
S
S
C
S
S
S
R
Q
N
L
T
L
Site 16
S131
K
G
S
S
C
S
S
S
R
Q
N
L
T
L
S
Site 17
T136
S
S
S
R
Q
N
L
T
L
S
L
S
S
T
K
Site 18
S138
S
R
Q
N
L
T
L
S
L
S
S
T
K
D
K
Site 19
S140
Q
N
L
T
L
S
L
S
S
T
K
D
K
G
S
Site 20
T142
L
T
L
S
L
S
S
T
K
D
K
G
S
Q
V
Site 21
S147
S
S
T
K
D
K
G
S
Q
V
C
N
Y
A
N
Site 22
Y152
K
G
S
Q
V
C
N
Y
A
N
G
G
L
F
S
Site 23
S159
Y
A
N
G
G
L
F
S
K
Y
S
G
S
A
Q
Site 24
Y161
N
G
G
L
F
S
K
Y
S
G
S
A
Q
S
L
Site 25
S162
G
G
L
F
S
K
Y
S
G
S
A
Q
S
L
A
Site 26
S167
K
Y
S
G
S
A
Q
S
L
A
S
V
Q
S
V
Site 27
S170
G
S
A
Q
S
L
A
S
V
Q
S
V
N
S
C
Site 28
S173
Q
S
L
A
S
V
Q
S
V
N
S
C
H
S
C
Site 29
T229
R
R
W
E
Q
A
L
T
F
R
N
R
Q
A
E
Site 30
S242
A
E
D
E
A
C
G
S
I
K
L
G
A
G
D
Site 31
S261
E
N
V
D
D
I
I
S
T
E
F
I
H
K
L
Site 32
Y276
E
A
L
L
Q
R
A
Y
R
L
Q
E
E
F
E
Site 33
T285
L
Q
E
E
F
E
A
T
L
G
A
S
D
P
N
Site 34
S289
F
E
A
T
L
G
A
S
D
P
N
S
L
A
D
Site 35
S293
L
G
A
S
D
P
N
S
L
A
D
D
I
D
K
Site 36
T302
A
D
D
I
D
K
D
T
D
I
T
M
K
G
N
Site 37
T305
I
D
K
D
T
D
I
T
M
K
G
N
V
E
D
Site 38
T318
E
D
F
G
L
R
D
T
L
S
I
A
S
T
D
Site 39
S323
R
D
T
L
S
I
A
S
T
D
S
F
A
S
A
Site 40
S326
L
S
I
A
S
T
D
S
F
A
S
A
A
E
L
Site 41
S329
A
S
T
D
S
F
A
S
A
A
E
L
A
E
H
Site 42
T342
E
H
R
E
V
R
H
T
Y
S
L
E
S
L
C
Site 43
Y343
H
R
E
V
R
H
T
Y
S
L
E
S
L
C
H
Site 44
S344
R
E
V
R
H
T
Y
S
L
E
S
L
C
H
C
Site 45
Y367
L
V
E
E
G
K
I
Y
S
R
V
L
R
T
E
Site 46
S400
Q
A
F
Q
V
I
L
S
E
S
A
N
R
I
F
Site 47
S402
F
Q
V
I
L
S
E
S
A
N
R
I
F
L
A
Site 48
S411
N
R
I
F
L
A
E
S
G
R
K
I
L
S
A
Site 49
S417
E
S
G
R
K
I
L
S
A
L
I
V
K
A
R
Site 50
Y439
D
V
F
D
E
M
I
Y
F
L
E
Q
T
D
H
Site 51
S476
L
D
F
I
L
M
D
S
F
E
D
L
E
N
P
Site 52
T485
E
D
L
E
N
P
P
T
S
I
Q
N
V
V
N
Site 53
S486
D
L
E
N
P
P
T
S
I
Q
N
V
V
N
N
Site 54
S499
N
N
R
W
L
N
S
S
F
K
E
T
A
V
A
Site 55
T503
L
N
S
S
F
K
E
T
A
V
A
S
S
C
W
Site 56
S508
K
E
T
A
V
A
S
S
C
W
S
V
L
K
Q
Site 57
S511
A
V
A
S
S
C
W
S
V
L
K
Q
K
R
Q
Site 58
Y578
F
D
F
E
K
V
R
Y
S
S
T
E
T
L
A
Site 59
S579
D
F
E
K
V
R
Y
S
S
T
E
T
L
A
E
Site 60
S580
F
E
K
V
R
Y
S
S
T
E
T
L
A
E
D
Site 61
T581
E
K
V
R
Y
S
S
T
E
T
L
A
E
D
L
Site 62
T583
V
R
Y
S
S
T
E
T
L
A
E
D
L
M
Q
Site 63
T611
E
A
D
A
L
R
H
T
S
S
C
L
S
S
H
Site 64
S612
A
D
A
L
R
H
T
S
S
C
L
S
S
H
G
Site 65
S613
D
A
L
R
H
T
S
S
C
L
S
S
H
G
H
Site 66
S616
R
H
T
S
S
C
L
S
S
H
G
H
V
M
S
Site 67
S617
H
T
S
S
C
L
S
S
H
G
H
V
M
S
T
Site 68
S623
S
S
H
G
H
V
M
S
T
G
L
L
E
A
K
Site 69
T624
S
H
G
H
V
M
S
T
G
L
L
E
A
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation