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Updated November 2019
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Protein Info
Short Name:
ZBTB38
Full Name:
Zinc finger and BTB domain-containing protein 38
Alias:
CIBZ; FLJ35036; ZBT38; zinc finger and BTB domain containing 38; zinc finger and BTB domain-containing 38
Type:
Mass (Da):
134257
Number AA:
1195
UniProt ID:
Q8NAP3
International Prot ID:
IPI00168056
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045944
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
D
L
K
D
D
F
H
S
D
T
V
L
S
I
L
Site 2
T18
K
D
D
F
H
S
D
T
V
L
S
I
L
N
E
Site 3
T95
L
N
Y
I
Y
S
S
T
V
V
V
K
R
Q
E
Site 4
T105
V
K
R
Q
E
T
V
T
D
L
A
A
A
G
K
Site 5
S117
A
G
K
K
L
G
I
S
F
L
E
D
L
T
D
Site 6
T123
I
S
F
L
E
D
L
T
D
R
N
F
S
N
S
Site 7
S128
D
L
T
D
R
N
F
S
N
S
P
G
P
Y
V
Site 8
S130
T
D
R
N
F
S
N
S
P
G
P
Y
V
F
C
Site 9
Y134
F
S
N
S
P
G
P
Y
V
F
C
I
T
E
K
Site 10
T159
R
H
E
E
P
A
I
T
N
G
P
R
I
T
N
Site 11
S169
P
R
I
T
N
A
F
S
I
I
E
T
E
N
S
Site 12
T173
N
A
F
S
I
I
E
T
E
N
S
N
N
M
F
Site 13
S176
S
I
I
E
T
E
N
S
N
N
M
F
S
P
L
Site 14
S181
E
N
S
N
N
M
F
S
P
L
D
L
R
A
S
Site 15
S188
S
P
L
D
L
R
A
S
F
K
K
V
S
D
S
Site 16
S193
R
A
S
F
K
K
V
S
D
S
M
R
T
A
S
Site 17
S195
S
F
K
K
V
S
D
S
M
R
T
A
S
L
C
Site 18
S200
S
D
S
M
R
T
A
S
L
C
L
E
R
T
D
Site 19
T217
H
E
A
E
P
V
R
T
L
A
E
H
S
Y
A
Site 20
Y223
R
T
L
A
E
H
S
Y
A
V
S
S
V
A
E
Site 21
S226
A
E
H
S
Y
A
V
S
S
V
A
E
A
Y
R
Site 22
S234
S
V
A
E
A
Y
R
S
Q
P
V
R
E
H
D
Site 23
S243
P
V
R
E
H
D
G
S
S
P
G
N
T
G
K
Site 24
S244
V
R
E
H
D
G
S
S
P
G
N
T
G
K
E
Site 25
T248
D
G
S
S
P
G
N
T
G
K
E
N
C
E
A
Site 26
T262
A
L
A
A
K
P
K
T
C
R
K
P
K
T
F
Site 27
T268
K
T
C
R
K
P
K
T
F
S
I
P
Q
D
S
Site 28
S270
C
R
K
P
K
T
F
S
I
P
Q
D
S
D
S
Site 29
S275
T
F
S
I
P
Q
D
S
D
S
A
T
E
N
I
Site 30
S277
S
I
P
Q
D
S
D
S
A
T
E
N
I
P
P
Site 31
T279
P
Q
D
S
D
S
A
T
E
N
I
P
P
P
P
Site 32
S288
N
I
P
P
P
P
V
S
N
L
E
V
N
Q
E
Site 33
S297
L
E
V
N
Q
E
R
S
P
Q
P
A
A
V
L
Site 34
T305
P
Q
P
A
A
V
L
T
R
S
K
S
P
N
N
Site 35
S307
P
A
A
V
L
T
R
S
K
S
P
N
N
E
G
Site 36
S309
N
E
G
D
V
H
F
S
R
E
D
E
N
Q
S
Site 37
S327
R
E
D
E
N
Q
S
S
D
V
P
G
P
P
A
Site 38
T355
S
K
A
F
D
S
S
T
L
L
S
A
H
M
Q
Site 39
S358
F
D
S
S
T
L
L
S
A
H
M
Q
L
H
K
Site 40
T367
H
M
Q
L
H
K
P
T
Q
E
P
L
V
C
K
Site 41
Y375
Q
E
P
L
V
C
K
Y
C
N
K
Q
F
T
T
Site 42
Y412
N
Q
R
F
L
E
N
Y
P
T
I
G
Q
N
G
Site 43
T414
R
F
L
E
N
Y
P
T
I
G
Q
N
G
G
S
Site 44
S421
T
I
G
Q
N
G
G
S
F
T
G
P
E
P
L
Site 45
S430
T
G
P
E
P
L
L
S
E
N
R
I
G
E
F
Site 46
S438
E
N
R
I
G
E
F
S
S
T
G
S
T
L
P
Site 47
S439
N
R
I
G
E
F
S
S
T
G
S
T
L
P
D
Site 48
T440
R
I
G
E
F
S
S
T
G
S
T
L
P
D
T
Site 49
S442
G
E
F
S
S
T
G
S
T
L
P
D
T
D
H
Site 50
T443
E
F
S
S
T
G
S
T
L
P
D
T
D
H
M
Site 51
T447
T
G
S
T
L
P
D
T
D
H
M
V
K
F
V
Site 52
T471
V
C
K
R
S
Y
V
T
L
S
S
L
R
R
H
Site 53
S473
K
R
S
Y
V
T
L
S
S
L
R
R
H
A
N
Site 54
S474
R
S
Y
V
T
L
S
S
L
R
R
H
A
N
V
Site 55
Y492
R
R
T
Y
P
C
H
Y
C
N
K
V
F
A
L
Site 56
Y502
K
V
F
A
L
A
E
Y
R
T
R
H
E
I
W
Site 57
T511
T
R
H
E
I
W
H
T
G
E
R
R
Y
Q
C
Site 58
Y516
W
H
T
G
E
R
R
Y
Q
C
I
F
C
L
E
Site 59
Y529
L
E
T
F
M
T
Y
Y
I
L
K
N
H
Q
K
Site 60
S546
H
A
I
D
H
R
L
S
I
S
K
K
T
A
N
Site 61
S548
I
D
H
R
L
S
I
S
K
K
T
A
N
G
G
Site 62
S559
A
N
G
G
L
K
P
S
V
Y
P
Y
K
L
Y
Site 63
Y561
G
G
L
K
P
S
V
Y
P
Y
K
L
Y
R
L
Site 64
Y563
L
K
P
S
V
Y
P
Y
K
L
Y
R
L
L
P
Site 65
Y566
S
V
Y
P
Y
K
L
Y
R
L
L
P
M
K
C
Site 66
Y578
M
K
C
K
R
A
P
Y
K
S
Y
R
N
S
S
Site 67
S580
C
K
R
A
P
Y
K
S
Y
R
N
S
S
Y
E
Site 68
Y581
K
R
A
P
Y
K
S
Y
R
N
S
S
Y
E
N
Site 69
S584
P
Y
K
S
Y
R
N
S
S
Y
E
N
A
R
E
Site 70
S585
Y
K
S
Y
R
N
S
S
Y
E
N
A
R
E
N
Site 71
Y586
K
S
Y
R
N
S
S
Y
E
N
A
R
E
N
S
Site 72
S593
Y
E
N
A
R
E
N
S
Q
M
N
E
S
A
P
Site 73
T602
M
N
E
S
A
P
G
T
Y
V
V
Q
N
P
H
Site 74
Y603
N
E
S
A
P
G
T
Y
V
V
Q
N
P
H
S
Site 75
S610
Y
V
V
Q
N
P
H
S
S
E
L
P
T
L
N
Site 76
S611
V
V
Q
N
P
H
S
S
E
L
P
T
L
N
F
Site 77
T615
P
H
S
S
E
L
P
T
L
N
F
Q
D
T
V
Site 78
T621
P
T
L
N
F
Q
D
T
V
N
T
L
T
N
S
Site 79
T624
N
F
Q
D
T
V
N
T
L
T
N
S
P
A
I
Site 80
T626
Q
D
T
V
N
T
L
T
N
S
P
A
I
P
L
Site 81
S628
T
V
N
T
L
T
N
S
P
A
I
P
L
E
T
Site 82
T643
S
A
C
Q
D
I
P
T
S
A
N
V
Q
N
A
Site 83
S644
A
C
Q
D
I
P
T
S
A
N
V
Q
N
A
E
Site 84
S670
D
L
D
N
N
F
Y
S
T
E
V
S
V
S
S
Site 85
S674
N
F
Y
S
T
E
V
S
V
S
S
T
E
N
A
Site 86
S677
S
T
E
V
S
V
S
S
T
E
N
A
V
S
S
Site 87
T678
T
E
V
S
V
S
S
T
E
N
A
V
S
S
D
Site 88
S695
A
G
D
V
P
V
L
S
L
S
N
S
S
E
N
Site 89
S697
D
V
P
V
L
S
L
S
N
S
S
E
N
A
A
Site 90
S699
P
V
L
S
L
S
N
S
S
E
N
A
A
S
V
Site 91
S705
N
S
S
E
N
A
A
S
V
I
S
Y
S
G
S
Site 92
S708
E
N
A
A
S
V
I
S
Y
S
G
S
A
P
S
Site 93
S715
S
Y
S
G
S
A
P
S
V
I
V
H
S
S
Q
Site 94
S725
V
H
S
S
Q
F
S
S
V
I
M
H
S
N
A
Site 95
S739
A
I
A
A
M
T
S
S
N
H
R
A
F
S
D
Site 96
S745
S
S
N
H
R
A
F
S
D
P
A
V
S
Q
S
Site 97
S750
A
F
S
D
P
A
V
S
Q
S
L
K
D
D
S
Site 98
S752
S
D
P
A
V
S
Q
S
L
K
D
D
S
K
P
Site 99
S757
S
Q
S
L
K
D
D
S
K
P
E
P
D
K
V
Site 100
S769
D
K
V
G
R
F
A
S
R
P
K
S
I
K
E
Site 101
S773
R
F
A
S
R
P
K
S
I
K
E
K
K
K
T
Site 102
T780
S
I
K
E
K
K
K
T
T
S
H
T
R
G
E
Site 103
S782
K
E
K
K
K
T
T
S
H
T
R
G
E
I
P
Site 104
S792
R
G
E
I
P
E
E
S
N
Y
V
A
D
P
G
Site 105
Y794
E
I
P
E
E
S
N
Y
V
A
D
P
G
G
S
Site 106
S801
Y
V
A
D
P
G
G
S
L
S
K
T
T
N
I
Site 107
S803
A
D
P
G
G
S
L
S
K
T
T
N
I
A
E
Site 108
T805
P
G
G
S
L
S
K
T
T
N
I
A
E
E
T
Site 109
T817
E
E
T
S
K
I
E
T
Y
I
A
K
P
A
L
Site 110
T827
A
K
P
A
L
P
G
T
S
T
N
S
N
V
A
Site 111
T829
P
A
L
P
G
T
S
T
N
S
N
V
A
P
L
Site 112
S831
L
P
G
T
S
T
N
S
N
V
A
P
L
C
Q
Site 113
S856
V
K
R
H
I
L
G
S
K
L
F
Y
K
R
G
Site 114
Y860
I
L
G
S
K
L
F
Y
K
R
G
R
R
P
K
Site 115
Y868
K
R
G
R
R
P
K
Y
Q
M
Q
E
E
P
L
Site 116
S884
Q
G
N
D
P
E
P
S
G
D
S
P
L
G
L
Site 117
S887
D
P
E
P
S
G
D
S
P
L
G
L
C
Q
S
Site 118
S894
S
P
L
G
L
C
Q
S
E
C
M
E
M
S
E
Site 119
S900
Q
S
E
C
M
E
M
S
E
V
F
D
D
A
S
Site 120
S907
S
E
V
F
D
D
A
S
D
Q
D
S
T
D
K
Site 121
S911
D
D
A
S
D
Q
D
S
T
D
K
P
W
R
P
Site 122
T912
D
A
S
D
Q
D
S
T
D
K
P
W
R
P
Y
Site 123
Y919
T
D
K
P
W
R
P
Y
Y
N
Y
K
P
K
K
Site 124
Y920
D
K
P
W
R
P
Y
Y
N
Y
K
P
K
K
K
Site 125
Y922
P
W
R
P
Y
Y
N
Y
K
P
K
K
K
S
R
Site 126
S947
R
K
E
H
G
N
R
S
P
S
H
K
C
K
Y
Site 127
S949
E
H
G
N
R
S
P
S
H
K
C
K
Y
P
A
Site 128
Y954
S
P
S
H
K
C
K
Y
P
A
E
L
D
C
A
Site 129
T976
K
P
F
E
E
E
E
T
K
E
M
P
K
L
Q
Site 130
T1006
G
R
P
H
R
H
L
T
S
R
P
Y
A
C
E
Site 131
Y1010
R
H
L
T
S
R
P
Y
A
C
E
L
C
A
K
Site 132
S1021
L
C
A
K
Q
F
Q
S
P
S
T
L
K
M
H
Site 133
S1023
A
K
Q
F
Q
S
P
S
T
L
K
M
H
M
R
Site 134
T1033
K
M
H
M
R
C
H
T
G
E
K
P
Y
Q
C
Site 135
Y1038
C
H
T
G
E
K
P
Y
Q
C
K
T
C
G
R
Site 136
S1048
K
T
C
G
R
C
F
S
V
Q
G
N
L
Q
K
Site 137
T1089
K
I
H
E
R
I
H
T
G
E
K
R
Y
H
C
Site 138
Y1105
F
C
F
Q
R
F
L
Y
L
S
T
K
R
N
H
Site 139
S1107
F
Q
R
F
L
Y
L
S
T
K
R
N
H
E
Q
Site 140
Y1125
R
E
H
N
G
K
G
Y
A
C
F
Q
C
P
K
Site 141
S1151
Q
K
K
H
L
F
K
S
P
S
Q
Q
E
K
I
Site 142
S1153
K
H
L
F
K
S
P
S
Q
Q
E
K
I
G
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation