PhosphoNET

           
Protein Info 
   
Short Name:  UNC13C
Full Name:  Protein unc-13 homolog C
Alias:  Munc13-3; UN13C; Unc-13 homologue C
Type:  Plasma membrane, Cytoplasm, Synapse, Cell junction protein
Mass (Da):  250911
Number AA:  2214
UniProt ID:  Q8NB66
International Prot ID:  IPI00739565
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0005737  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0008270     PhosphoSite+ KinaseNET
Biological Process:  GO:0006887  GO:0007242   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T46KKDQDFPTAGQTKSP
Site 2T50DFPTAGQTKSPKFSY
Site 3S52PTAGQTKSPKFSYTF
Site 4S56QTKSPKFSYTFKSTV
Site 5Y57TKSPKFSYTFKSTVK
Site 6T58KSPKFSYTFKSTVKK
Site 7S61KFSYTFKSTVKKIAK
Site 8S71KKIAKCSSTHNLSTE
Site 9T72KIAKCSSTHNLSTEE
Site 10S76CSSTHNLSTEEDEAS
Site 11S83STEEDEASKEFSLSP
Site 12S87DEASKEFSLSPTFSY
Site 13S89ASKEFSLSPTFSYRV
Site 14T91KEFSLSPTFSYRVAI
Site 15S111KNAKVTNSDNEDLLQ
Site 16S121EDLLQELSSIESSYS
Site 17S122DLLQELSSIESSYSE
Site 18S125QELSSIESSYSESLN
Site 19S126ELSSIESSYSESLNE
Site 20S128SSIESSYSESLNELR
Site 21S130IESSYSESLNELRSS
Site 22S136ESLNELRSSTENQAQ
Site 23S137SLNELRSSTENQAQS
Site 24T138LNELRSSTENQAQST
Site 25S156PVRRNRKSSSSLAPS
Site 26S157VRRNRKSSSSLAPSE
Site 27S158RRNRKSSSSLAPSEG
Site 28S159RNRKSSSSLAPSEGS
Site 29S163SSSSLAPSEGSSDGE
Site 30S167LAPSEGSSDGERTLH
Site 31S190KLRKWKKSQECVSSD
Site 32S195KKSQECVSSDSELST
Site 33S196KSQECVSSDSELSTM
Site 34S198QECVSSDSELSTMKK
Site 35S201VSSDSELSTMKKSWG
Site 36T202SSDSELSTMKKSWGI
Site 37S206ELSTMKKSWGIRSKS
Site 38S213SWGIRSKSLDRTVRN
Site 39T217RSKSLDRTVRNPKTN
Site 40T223RTVRNPKTNALEPGF
Site 41S231NALEPGFSSSGCISQ
Site 42S233LEPGFSSSGCISQTH
Site 43S237FSSSGCISQTHDVME
Site 44T258QGISQIETELSELRG
Site 45S261SQIETELSELRGHVN
Site 46S273HVNALKHSIDEISSS
Site 47S280SIDEISSSVEVVQSE
Site 48S286SSVEVVQSEIEQLRT
Site 49T293SEIEQLRTGFVQSRR
Site 50S298LRTGFVQSRRETRDI
Site 51T302FVQSRRETRDIHDYI
Site 52Y308ETRDIHDYIKHLGHM
Site 53S317KHLGHMGSKASLRFL
Site 54S320GHMGSKASLRFLNVT
Site 55T327SLRFLNVTEERFEYV
Site 56Y333VTEERFEYVESVVYQ
Site 57S349LIDKMGFSDAPNAIK
Site 58Y380KPRPILVYFETPQQR
Site 59T383PILVYFETPQQRDSV
Site 60S389ETPQQRDSVLKKSYK
Site 61S394RDSVLKKSYKLKGTG
Site 62S405KGTGIGISTDILTHD
Site 63T410GISTDILTHDIRERK
Site 64S424KEKGIPSSQTYESMA
Site 65Y427GIPSSQTYESMAIKL
Site 66S429PSSQTYESMAIKLST
Site 67S435ESMAIKLSTPEPKIK
Site 68T436SMAIKLSTPEPKIKK
Site 69S448IKKNNWQSPDDSDED
Site 70S452NWQSPDDSDEDLESD
Site 71S458DSDEDLESDLNRNSY
Site 72S464ESDLNRNSYAVLSKS
Site 73Y465SDLNRNSYAVLSKSE
Site 74S469RNSYAVLSKSELLTK
Site 75S471SYAVLSKSELLTKGS
Site 76T475LSKSELLTKGSTSKP
Site 77S478SELLTKGSTSKPSSK
Site 78T479ELLTKGSTSKPSSKS
Site 79S480LLTKGSTSKPSSKSH
Site 80S483KGSTSKPSSKSHSAR
Site 81S484GSTSKPSSKSHSARS
Site 82S486TSKPSSKSHSARSKN
Site 83S488KPSSKSHSARSKNKT
Site 84T495SARSKNKTANSSRIS
Site 85S498SKNKTANSSRISNKS
Site 86S502TANSSRISNKSDYDK
Site 87S505SSRISNKSDYDKISS
Site 88Y507RISNKSDYDKISSQL
Site 89S511KSDYDKISSQLPESD
Site 90S512SDYDKISSQLPESDI
Site 91S517ISSQLPESDILEKQT
Site 92T525DILEKQTTTHYADAT
Site 93Y528EKQTTTHYADATPLW
Site 94T532TTHYADATPLWHSQS
Site 95S537DATPLWHSQSDFFTA
Site 96S539TPLWHSQSDFFTAKL
Site 97T543HSQSDFFTAKLSRSE
Site 98S547 DFFTAKLSRSESDFS
Site 99S549 FTAKLSRSESDFSKL
Site 100S551AKLSRSESDFSKLCQ
Site 101S554SRSESDFSKLCQSYS
Site 102S559DFSKLCQSYSEDFSE
Site 103S561SKLCQSYSEDFSENQ
Site 104S565QSYSEDFSENQFFTR
Site 105T573ENQFFTRTNGSSLLS
Site 106S576FFTRTNGSSLLSSSD
Site 107S577FTRTNGSSLLSSSDR
Site 108S580TNGSSLLSSSDRELW
Site 109S581NGSSLLSSSDRELWQ
Site 110S582GSSLLSSSDRELWQR
Site 111T596RKQEGTATLYDSPKD
Site 112Y598QEGTATLYDSPKDQH
Site 113S600GTATLYDSPKDQHLN
Site 114T622GQTETENTETVDSGM
Site 115T624TETENTETVDSGMSN
Site 116S627ENTETVDSGMSNGMV
Site 117S637SNGMVCASGDRSHYS
Site 118S641VCASGDRSHYSDSQL
Site 119Y643ASGDRSHYSDSQLSL
Site 120S644SGDRSHYSDSQLSLH
Site 121S646DRSHYSDSQLSLHED
Site 122S649HYSDSQLSLHEDLSP
Site 123S655LSLHEDLSPWKEWNQ
Site 124S670GADLGLDSSTQEGFD
Site 125S671ADLGLDSSTQEGFDY
Site 126T672DLGLDSSTQEGFDYE
Site 127Y678STQEGFDYETNSLFD
Site 128T680QEGFDYETNSLFDQQ
Site 129S682GFDYETNSLFDQQLD
Site 130Y691FDQQLDVYNKDLEYL
Site 131Y697VYNKDLEYLGKCHSD
Site 132S703EYLGKCHSDLQDDSE
Site 133S709HSDLQDDSESYDLTQ
Site 134S711DLQDDSESYDLTQDD
Site 135T715DSESYDLTQDDNSSP
Site 136S720DLTQDDNSSPCPGLD
Site 137S721LTQDDNSSPCPGLDN
Site 138Y738QGQWVGQYDSYQGAN
Site 139Y741WVGQYDSYQGANSNE
Site 140Y750GANSNELYQNQNQLS
Site 141S762QLSMMYRSQSELQSD
Site 142S764SMMYRSQSELQSDDS
Site 143S768RSQSELQSDDSEDAP
Site 144S771SELQSDDSEDAPPKS
Site 145S778SEDAPPKSWHSRLSI
Site 146S781APPKSWHSRLSIDLS
Site 147S784KSWHSRLSIDLSDKT
Site 148S788SRLSIDLSDKTFSFP
Site 149T791SIDLSDKTFSFPKFG
Site 150S793DLSDKTFSFPKFGST
Site 151S799FSFPKFGSTLQRAKS
Site 152T800SFPKFGSTLQRAKSA
Site 153S806STLQRAKSALEVVWN
Site 154S815LEVVWNKSTQSLSGY
Site 155T816EVVWNKSTQSLSGYE
Site 156S818VWNKSTQSLSGYEDS
Site 157S820NKSTQSLSGYEDSGS
Site 158Y822STQSLSGYEDSGSSL
Site 159S825SLSGYEDSGSSLMGR
Site 160S827SGYEDSGSSLMGRFR
Site 161S828GYEDSGSSLMGRFRT
Site 162T835SLMGRFRTLSQSTAN
Site 163S837MGRFRTLSQSTANES
Site 164S839RFRTLSQSTANESST
Site 165S844SQSTANESSTTLDSD
Site 166T846STANESSTTLDSDVY
Site 167T847TANESSTTLDSDVYT
Site 168S850ESSTTLDSDVYTEPY
Site 169Y853TTLDSDVYTEPYYYK
Site 170T854TLDSDVYTEPYYYKA
Site 171Y858DVYTEPYYYKAEDEE
Site 172Y859VYTEPYYYKAEDEED
Site 173Y867KAEDEEDYTEPVADN
Site 174T868AEDEEDYTEPVADNE
Site 175T876EPVADNETDYVEVME
Site 176Y878VADNETDYVEVMEQV
Site 177S894AKLENRTSITETDEQ
Site 178T898NRTSITETDEQMQAY
Site 179Y905TDEQMQAYDHLSYET
Site 180Y910QAYDHLSYETPYETP
Site 181T912YDHLSYETPYETPQD
Site 182Y914HLSYETPYETPQDEG
Site 183T916SYETPYETPQDEGYD
Site 184Y922ETPQDEGYDGPADDM
Site 185S931GPADDMVSEEGLEPL
Site 186S971KPKRIRPSFKEAALR
Site 187Y980KEAALRAYKKQMAEL
Site 188S997KILAGDSSSVDEKAR
Site 189S998ILAGDSSSVDEKARI
Site 190S1007DEKARIVSGNDLDAS
Site 191S1014SGNDLDASKFSALQV
Site 192Y1030GGAGGGLYGIDSMPD
Site 193S1034GGLYGIDSMPDLRRK
Site 194T1043PDLRRKKTLPIVRDV
Site 195S1070LAMVIRTSLNNEELK
Site 196T1107FEVWTATTPTYCYEC
Site 197Y1110WTATTPTYCYECEGL
Site 198Y1112ATTPTYCYECEGLLW
Site 199S1155LQRAAEKSSKHGAED
Site 200T1164KHGAEDKTQTIITAM
Site 201T1215KQSVLDGTSKWSAKI
Site 202S1216QSVLDGTSKWSAKIT
Site 203T1238GLQAKDKTGSSDPYV
Site 204S1240QAKDKTGSSDPYVTV
Site 205S1241AKDKTGSSDPYVTVQ
Site 206Y1244KTGSSDPYVTVQVGK
Site 207T1246GSSDPYVTVQVGKNK
Site 208T1256VGKNKRRTKTIFGNL
Site 209T1258KNKRRTKTIFGNLNP
Site 210S1295DEDDDIKSRVKQHFK
Site 211S1305KQHFKKESDDFLGQT
Site 212Y1327SGEMDVWYNLEKRTD
Site 213S1336LEKRTDKSAVSGAIR
Site 214S1339RTDKSAVSGAIRLKI
Site 215Y1363VAPYHIQYTCLHENL
Site 216Y1373LHENLFHYLTEVKSN
Site 217T1375ENLFHYLTEVKSNGG
Site 218S1379HYLTEVKSNGGVKIP
Site 219S1402KVFFDDASQEIVDEF
Site 220Y1413 VDEFAMRYGIESIYQ
Site 221Y1419RYGIESIYQAMTHFS
Site 222T1423ESIYQAMTHFSCLSS
Site 223S1466TNIQVSASDRFAATN
Site 224S1489LLDQLHNSLRIDLSK
Site 225S1495NSLRIDLSKYRENFP
Site 226Y1497LRIDLSKYRENFPAS
Site 227S1504YRENFPASNTERLQD
Site 228S1514ERLQDLKSTVDLLTS
Site 229T1515RLQDLKSTVDLLTSI
Site 230S1534MKVLELQSPPKASMV
Site 231Y1554RACLDSTYKYIFDNC
Site 232Y1556CLDSTYKYIFDNCHE
Site 233S1566DNCHELYSQLTDPSK
Site 234T1569HELYSQLTDPSKKQD
Site 235T1608TIIDEDKTAYTPVLN
Site 236T1611DEDKTAYTPVLNQFP
Site 237Y1641LFALDMKYALEEHEN
Site 238Y1657RLCKSTDYMNLHFKV
Site 239Y1671VKWFYNEYVRELPAF
Site 240Y1685FKDAVPEYSLWFEPF
Site 241S1686KDAVPEYSLWFEPFV
Site 242S1704LDENEDVSMEFLHGA
Site 243S1782QYAAIVSSDFSSHCD
Site 244S1785AIVSSDFSSHCDKEN
Site 245S1786IVSSDFSSHCDKENV
Site 246S1822MGGKELDSEASTILK
Site 247T1826ELDSEASTILKELQV
Site 248T1874QMRANGNTTSNKNSA
Site 249S1876RANGNTTSNKNSAAM
Site 250S1880NTTSNKNSAAMDAEI
Site 251S1903LDKTLSLSAKICEKT
Site 252T1910SAKICEKTVLKRVLK
Site 253T1937QIVLPPLTDQTGPQM
Site 254S1956AKDLGQLSKLKEHMI
Site 255T1971REDARGLTPRQCAIM
Site 256S2004KKNFLEKSPDLQSLR
Site 257S2009EKSPDLQSLRYALSL
Site 258S2015QSLRYALSLYTQTTD
Site 259T2031LIKKFIDTQTSQSRS
Site 260T2033KKFIDTQTSQSRSSK
Site 261S2034KFIDTQTSQSRSSKD
Site 262S2036IDTQTSQSRSSKDAV
Site 263S2038TQTSQSRSSKDAVGQ
Site 264S2039QTSQSRSSKDAVGQI
Site 265T2055VHVDITATPGTGDHK
Site 266T2103DKKRKQGTKTKSNTW
Site 267T2105KRKQGTKTKSNTWSP
Site 268S2107KQGTKTKSNTWSPKY
Site 269T2109GTKTKSNTWSPKYNE
Site 270S2111KTKSNTWSPKYNETF
Site 271Y2114SNTWSPKYNETFQFI
Site 272Y2140LHLSVKDYCFAREDR
Site 273S2164QNIAEKGSYGAWYPL
Site 274Y2165NIAEKGSYGAWYPLL
Site 275Y2169KGSYGAWYPLLKNIS
Site 276S2176YPLLKNISMDETGLT
Site 277S2189LTILRILSQRTSDDV
Site 278S2193RILSQRTSDDVAKEF
Site 279S2205KEFVRLKSETRSTEE
Site 280T2207FVRLKSETRSTEESA
Site 281S2209RLKSETRSTEESA__
Site 282T2210LKSETRSTEESA___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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