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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FANCB
Full Name:
Fanconi anemia group B protein
Alias:
FAAP95; Fanconi anemia-associated polypeptide of 95 kDa; Protein FACB
Type:
Mass (Da):
97726
Number AA:
859
UniProt ID:
Q8NB91
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
E
V
L
V
F
Q
L
S
K
G
N
F
A
D
K
Site 2
T38
N
F
A
D
K
E
P
T
K
T
P
I
L
H
V
Site 3
T40
A
D
K
E
P
T
K
T
P
I
L
H
V
R
R
Site 4
T54
R
M
V
F
D
R
G
T
K
V
F
V
Q
K
S
Site 5
Y93
R
T
G
I
N
L
P
Y
I
V
I
E
K
N
K
Site 6
S123
N
K
F
E
M
R
L
S
F
K
L
G
Y
E
M
Site 7
Y128
R
L
S
F
K
L
G
Y
E
M
K
D
G
L
R
Site 8
S162
S
Q
T
G
K
V
V
S
V
S
G
N
F
S
S
Site 9
S168
V
S
V
S
G
N
F
S
S
I
Q
W
A
G
E
Site 10
S169
S
V
S
G
N
F
S
S
I
Q
W
A
G
E
I
Site 11
S192
G
L
K
E
C
C
L
S
E
E
E
C
T
Q
E
Site 12
T197
C
L
S
E
E
E
C
T
Q
E
P
S
K
S
D
Site 13
Y205
Q
E
P
S
K
S
D
Y
A
I
W
N
T
K
F
Site 14
S216
N
T
K
F
C
V
Y
S
L
E
S
Q
E
V
L
Site 15
S267
T
R
K
N
Q
L
I
S
F
Q
N
G
T
P
K
Site 16
T272
L
I
S
F
Q
N
G
T
P
K
N
V
C
Q
L
Site 17
S351
L
F
K
D
S
L
N
S
D
C
L
T
S
F
K
Site 18
S368
D
L
G
K
I
N
Y
S
S
E
P
S
D
C
N
Site 19
S369
L
G
K
I
N
Y
S
S
E
P
S
D
C
N
E
Site 20
S372
I
N
Y
S
S
E
P
S
D
C
N
E
D
D
L
Site 21
Y388
E
D
K
Q
E
N
R
Y
L
V
V
P
P
L
E
Site 22
S403
T
G
L
K
V
C
F
S
S
F
R
E
L
R
Q
Site 23
S404
G
L
K
V
C
F
S
S
F
R
E
L
R
Q
H
Site 24
S422
K
E
K
I
I
S
K
S
Y
K
A
L
I
N
L
Site 25
T437
V
Q
G
K
D
D
N
T
S
S
A
E
E
K
E
Site 26
S438
Q
G
K
D
D
N
T
S
S
A
E
E
K
E
C
Site 27
S439
G
K
D
D
N
T
S
S
A
E
E
K
E
C
L
Site 28
S456
L
C
G
E
E
E
N
S
V
H
I
L
D
E
K
Site 29
S465
H
I
L
D
E
K
L
S
D
N
F
Q
D
S
E
Site 30
S471
L
S
D
N
F
Q
D
S
E
Q
L
V
E
K
I
Site 31
Y480
Q
L
V
E
K
I
W
Y
R
V
I
D
D
S
L
Site 32
S496
V
G
V
K
T
T
S
S
L
K
L
S
L
N
D
Site 33
S500
T
T
S
S
L
K
L
S
L
N
D
V
T
L
S
Site 34
S516
L
M
D
Q
A
H
D
S
R
F
R
L
L
K
C
Site 35
S531
Q
N
R
V
I
K
L
S
T
N
P
F
P
A
P
Site 36
T553
G
L
E
A
K
R
V
T
L
T
P
D
S
K
K
Site 37
T555
E
A
K
R
V
T
L
T
P
D
S
K
K
E
E
Site 38
S558
R
V
T
L
T
P
D
S
K
K
E
E
S
F
V
Site 39
S563
P
D
S
K
K
E
E
S
F
V
C
E
H
P
S
Site 40
S606
L
Q
I
M
E
R
E
S
G
N
C
P
K
D
R
Site 41
Y614
G
N
C
P
K
D
R
Y
V
V
C
G
R
V
F
Site 42
Y632
E
D
L
S
T
G
K
Y
L
L
T
F
P
K
K
Site 43
T635
S
T
G
K
Y
L
L
T
F
P
K
K
K
P
I
Site 44
S664
K
S
C
F
Q
I
T
S
P
G
Y
A
L
N
S
Site 45
Y692
I
K
E
F
P
E
V
Y
F
C
E
R
P
G
S
Site 46
S699
Y
F
C
E
R
P
G
S
F
Y
G
T
L
F
T
Site 47
Y701
C
E
R
P
G
S
F
Y
G
T
L
F
T
W
K
Site 48
T703
R
P
G
S
F
Y
G
T
L
F
T
W
K
Q
R
Site 49
S751
L
K
N
L
K
S
G
S
E
N
F
L
I
D
N
Site 50
S791
F
M
Q
R
C
E
V
S
K
G
K
S
S
V
V
Site 51
S803
S
V
V
A
A
A
L
S
D
R
R
E
N
I
H
Site 52
Y835
L
K
V
S
G
A
L
Y
R
E
I
T
L
K
V
Site 53
T839
G
A
L
Y
R
E
I
T
L
K
V
A
E
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation