KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KY
Full Name:
Kyphoscoliosis peptidase
Alias:
Type:
Mass (Da):
63885
Number AA:
561
UniProt ID:
Q8NBH2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
D
M
L
L
I
V
H
S
E
K
R
R
A
A
Q
Site 2
T29
K
R
R
A
A
Q
G
T
L
S
D
Q
Q
A
N
Site 3
S31
R
A
A
Q
G
T
L
S
D
Q
Q
A
N
P
S
Site 4
S39
D
Q
Q
A
N
P
S
S
L
L
Q
R
G
G
G
Site 5
S83
Q
Q
P
Q
V
I
T
S
Y
N
S
Q
G
T
Q
Site 6
Y84
Q
P
Q
V
I
T
S
Y
N
S
Q
G
T
Q
L
Site 7
T92
N
S
Q
G
T
Q
L
T
V
E
V
H
P
R
D
Site 8
S109
P
Q
L
L
K
K
F
S
L
A
K
R
L
Q
G
Site 9
T122
Q
G
D
K
N
G
N
T
R
P
R
Q
P
G
G
Site 10
Y135
G
G
K
D
A
H
A
Y
P
W
D
R
S
S
L
Site 11
S140
H
A
Y
P
W
D
R
S
S
L
K
S
M
S
L
Site 12
S141
A
Y
P
W
D
R
S
S
L
K
S
M
S
L
D
Site 13
S144
W
D
R
S
S
L
K
S
M
S
L
D
L
Q
Q
Site 14
S146
R
S
S
L
K
S
M
S
L
D
L
Q
Q
F
E
Site 15
Y158
Q
F
E
K
L
D
I
Y
T
S
Q
V
T
A
K
Site 16
S160
E
K
L
D
I
Y
T
S
Q
V
T
A
K
S
G
Site 17
S166
T
S
Q
V
T
A
K
S
G
L
D
E
L
V
S
Site 18
S173
S
G
L
D
E
L
V
S
D
L
L
Q
E
A
H
Site 19
T223
D
I
L
R
T
Q
K
T
N
C
D
G
Y
A
G
Site 20
Y228
Q
K
T
N
C
D
G
Y
A
G
L
F
E
R
M
Site 21
T245
L
A
G
V
Q
C
M
T
V
P
G
Y
S
K
G
Site 22
Y249
Q
C
M
T
V
P
G
Y
S
K
G
F
G
Y
Q
Site 23
S250
C
M
T
V
P
G
Y
S
K
G
F
G
Y
Q
T
Site 24
Y255
G
Y
S
K
G
F
G
Y
Q
T
G
Q
S
F
S
Site 25
T257
S
K
G
F
G
Y
Q
T
G
Q
S
F
S
G
E
Site 26
S260
F
G
Y
Q
T
G
Q
S
F
S
G
E
F
D
H
Site 27
Y273
D
H
A
W
N
A
V
Y
L
E
G
R
W
H
L
Site 28
S283
G
R
W
H
L
V
D
S
T
W
G
S
G
L
V
Site 29
T284
R
W
H
L
V
D
S
T
W
G
S
G
L
V
D
Site 30
T298
D
T
I
T
S
K
F
T
F
L
Y
N
E
F
Y
Site 31
S332
Q
L
L
K
P
P
Q
S
L
R
Q
F
E
N
N
Site 32
Y341
R
Q
F
E
N
N
M
Y
H
K
S
E
F
Y
N
Site 33
S353
F
Y
N
K
G
M
L
S
A
H
P
E
T
S
M
Site 34
S359
L
S
A
H
P
E
T
S
M
I
R
T
V
N
G
Site 35
T363
P
E
T
S
M
I
R
T
V
N
G
K
A
T
V
Site 36
T369
R
T
V
N
G
K
A
T
V
T
I
E
S
C
A
Site 37
S394
K
Q
E
H
G
L
L
S
L
R
K
N
G
M
K
Site 38
Y405
N
G
M
K
L
E
V
Y
P
P
T
M
G
T
H
Site 39
Y425
A
K
G
N
S
D
I
Y
S
S
V
L
E
Y
T
Site 40
S426
K
G
N
S
D
I
Y
S
S
V
L
E
Y
T
L
Site 41
S427
G
N
S
D
I
Y
S
S
V
L
E
Y
T
L
K
Site 42
Y437
E
Y
T
L
K
C
N
Y
V
D
M
G
V
Q
L
Site 43
S455
L
H
Q
P
V
G
P
S
W
F
S
E
Q
M
G
Site 44
S476
P
D
P
I
I
H
T
S
D
G
R
C
S
I
S
Site 45
S481
H
T
S
D
G
R
C
S
I
S
F
S
V
E
E
Site 46
S483
S
D
G
R
C
S
I
S
F
S
V
E
E
G
I
Site 47
S495
E
G
I
N
V
L
A
S
L
H
G
D
D
G
P
Site 48
T504
H
G
D
D
G
P
I
T
E
E
T
Q
R
R
Y
Site 49
T507
D
G
P
I
T
E
E
T
Q
R
R
Y
I
F
Q
Site 50
Y511
T
E
E
T
Q
R
R
Y
I
F
Q
L
H
R
E
Site 51
Y556
F
Y
S
Y
I
L
K
Y
K
V
N
A
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation