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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM63B
Full Name:
Protein FAM63B
Alias:
fa63b; fam63b; family with sequence similarity 63, member B; kiaa1164; Nbla00402
Type:
Unknown function
Mass (Da):
67088
Number AA:
621
UniProt ID:
Q8NBR6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
E
S
S
P
E
S
L
Q
P
L
Site 2
S7
_
M
E
S
S
P
E
S
L
Q
P
L
E
H
G
Site 3
S21
G
V
A
A
G
P
A
S
G
T
G
S
S
Q
E
Site 4
S25
G
P
A
S
G
T
G
S
S
Q
E
G
L
Q
E
Site 5
S26
P
A
S
G
T
G
S
S
Q
E
G
L
Q
E
T
Site 6
S62
G
A
A
A
A
R
R
S
L
P
D
S
A
S
P
Site 7
S66
A
R
R
S
L
P
D
S
A
S
P
A
G
S
P
Site 8
S68
R
S
L
P
D
S
A
S
P
A
G
S
P
E
V
Site 9
S72
D
S
A
S
P
A
G
S
P
E
V
P
G
P
C
Site 10
S80
P
E
V
P
G
P
C
S
S
S
A
G
L
D
L
Site 11
S81
E
V
P
G
P
C
S
S
S
A
G
L
D
L
K
Site 12
S90
A
G
L
D
L
K
D
S
G
L
E
S
P
A
A
Site 13
S94
L
K
D
S
G
L
E
S
P
A
A
A
E
A
P
Site 14
Y106
E
A
P
L
R
G
Q
Y
K
V
T
A
S
P
E
Site 15
T109
L
R
G
Q
Y
K
V
T
A
S
P
E
T
A
V
Site 16
S111
G
Q
Y
K
V
T
A
S
P
E
T
A
V
A
G
Site 17
T144
G
T
C
Q
A
E
L
T
A
A
G
S
E
E
P
Site 18
S148
A
E
L
T
A
A
G
S
E
E
P
S
S
A
G
Site 19
S152
A
A
G
S
E
E
P
S
S
A
G
G
L
S
S
Site 20
S153
A
G
S
E
E
P
S
S
A
G
G
L
S
S
S
Site 21
S158
P
S
S
A
G
G
L
S
S
S
C
S
D
P
S
Site 22
S159
S
S
A
G
G
L
S
S
S
C
S
D
P
S
P
Site 23
S160
S
A
G
G
L
S
S
S
C
S
D
P
S
P
P
Site 24
S162
G
G
L
S
S
S
C
S
D
P
S
P
P
G
E
Site 25
S165
S
S
S
C
S
D
P
S
P
P
G
E
S
P
S
Site 26
S170
D
P
S
P
P
G
E
S
P
S
L
D
S
L
E
Site 27
S172
S
P
P
G
E
S
P
S
L
D
S
L
E
S
F
Site 28
S175
G
E
S
P
S
L
D
S
L
E
S
F
S
N
L
Site 29
S178
P
S
L
D
S
L
E
S
F
S
N
L
H
S
F
Site 30
S180
L
D
S
L
E
S
F
S
N
L
H
S
F
P
S
Site 31
S184
E
S
F
S
N
L
H
S
F
P
S
S
C
E
F
Site 32
S187
S
N
L
H
S
F
P
S
S
C
E
F
N
S
E
Site 33
S188
N
L
H
S
F
P
S
S
C
E
F
N
S
E
E
Site 34
T226
K
E
E
E
G
E
E
T
A
Q
V
L
A
A
S
Site 35
S233
T
A
Q
V
L
A
A
S
K
E
R
F
P
G
Q
Site 36
T255
I
Q
W
K
E
E
N
T
P
I
I
T
Q
N
E
Site 37
Y298
T
A
E
Q
L
M
E
Y
L
G
D
Y
M
L
D
Site 38
Y302
L
M
E
Y
L
G
D
Y
M
L
D
A
K
P
K
Site 39
Y319
S
E
I
Q
R
L
N
Y
E
Q
N
M
S
D
A
Site 40
S386
V
K
A
V
G
N
C
S
Y
N
Q
L
V
E
K
Site 41
S396
Q
L
V
E
K
I
I
S
C
K
Q
S
D
N
S
Site 42
S400
K
I
I
S
C
K
Q
S
D
N
S
E
L
V
S
Site 43
S403
S
C
K
Q
S
D
N
S
E
L
V
S
E
G
F
Site 44
S407
S
D
N
S
E
L
V
S
E
G
F
V
A
E
Q
Site 45
S433
H
G
L
C
E
L
T
S
T
V
Q
E
G
E
L
Site 46
Y455
H
F
S
T
M
T
K
Y
K
G
Q
L
Y
L
L
Site 47
Y460
T
K
Y
K
G
Q
L
Y
L
L
V
T
D
Q
G
Site 48
T470
V
T
D
Q
G
F
L
T
E
E
K
V
V
W
E
Site 49
S491
G
D
G
N
F
C
D
S
E
F
H
L
R
P
P
Site 50
S499
E
F
H
L
R
P
P
S
D
P
E
T
V
Y
K
Site 51
T503
R
P
P
S
D
P
E
T
V
Y
K
G
Q
Q
D
Site 52
Y516
Q
D
Q
I
D
Q
D
Y
L
M
A
L
S
L
Q
Site 53
S521
Q
D
Y
L
M
A
L
S
L
Q
Q
E
Q
Q
S
Site 54
S528
S
L
Q
Q
E
Q
Q
S
Q
E
I
N
W
E
Q
Site 55
S558
E
E
E
D
R
R
A
S
Q
Y
Y
Q
E
Q
E
Site 56
Y560
E
D
R
R
A
S
Q
Y
Y
Q
E
Q
E
Q
A
Site 57
Y561
D
R
R
A
S
Q
Y
Y
Q
E
Q
E
Q
A
A
Site 58
S587
Q
G
Q
P
A
Q
A
S
P
S
S
G
R
Q
S
Site 59
S589
Q
P
A
Q
A
S
P
S
S
G
R
Q
S
G
N
Site 60
S590
P
A
Q
A
S
P
S
S
G
R
Q
S
G
N
S
Site 61
S594
S
P
S
S
G
R
Q
S
G
N
S
E
R
K
R
Site 62
S597
S
G
R
Q
S
G
N
S
E
R
K
R
K
E
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation