PhosphoNET

           
Protein Info 
   
Short Name:  TMEM145
Full Name:  Transmembrane protein 145
Alias:  FLJ90805; TM145
Type: 
Mass (Da):  55585
Number AA:  493
UniProt ID:  Q8NBT3
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S22PLLLLLLSLPPRARA
Site 2Y31PPRARAKYVRGNLSS
Site 3S38YVRGNLSSKEDWVFL
Site 4Y54RFCFLSDYGRLDFRF
Site 5Y63RLDFRFRYPEAKCCQ
Site 6S123WSGCQVVSEEGTRYL
Site 7T127QVVSEEGTRYLSCSS
Site 8Y129VSEEGTRYLSCSSGR
Site 9S131EEGTRYLSCSSGRSF
Site 10S133GTRYLSCSSGRSFRS
Site 11S134TRYLSCSSGRSFRSG
Site 12S137LSCSSGRSFRSGDGL
Site 13S140SSGRSFRSGDGLQLE
Site 14Y148GDGLQLEYEMVLTNG
Site 15T153LEYEMVLTNGKSFWT
Site 16S164SFWTRHFSADEFGIL
Site 17T203KGRQLLHTTYKMFMA
Site 18T268LGKGFTVTRGRISHA
Site 19S273TVTRGRISHAGSVKL
Site 20Y309FDPGQVLYTYESPAG
Site 21Y311PGQVLYTYESPAGYG
Site 22S404FLIMTRPSAANKNFP
Site 23Y412AANKNFPYHVRTSQI
Site 24S421VRTSQIASAGVPGPG
Site 25S430GVPGPGGSQSADKAF
Site 26S432PGPGGSQSADKAFPQ
Site 27T446QHVYGNVTFISDSVP
Site 28T456SDSVPNFTELFSIPP
Site 29S460PNFTELFSIPPPATF
Site 30T466FSIPPPATFPLPRAA
Site 31S476LPRAAPDSGLPLFRD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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