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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAI-RBP1
Full Name:
Plasminogen activator inhibitor 1 RNA-binding protein
Alias:
CGI-55; PAIB; PAIRB; PAIRBP1; Plasminogen activator inhibitor 1 RNA-binding protein: PAI1 RNA-binding protein 1: SERPINE1 mRNA-binding protein 1: Plasminogen activator inhibitor 1 RNA-binding protein: PAI1 RNA-binding protein 1: SERPINE1 mRNA-binding protein 1; SERPINE1 mRNA binding protein 1
Type:
RNA binding protein
Mass (Da):
44965
Number AA:
408
UniProt ID:
Q8NC51
International Prot ID:
IPI00410693
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0003730
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0043488
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
D
Q
L
F
D
D
E
S
D
P
F
E
V
L
K
Site 2
S53
V
G
G
P
G
A
K
S
A
A
Q
A
A
A
Q
Site 3
T61
A
A
Q
A
A
A
Q
T
N
S
N
A
A
G
K
Site 4
S63
Q
A
A
A
Q
T
N
S
N
A
A
G
K
Q
L
Site 5
S74
G
K
Q
L
R
K
E
S
Q
K
D
R
K
N
P
Site 6
S85
R
K
N
P
L
P
P
S
V
G
V
V
D
K
K
Site 7
T95
V
V
D
K
K
E
E
T
Q
P
P
V
A
L
K
Site 8
S152
K
G
E
G
G
E
F
S
V
D
R
P
I
I
D
Site 9
S187
G
R
G
D
G
F
D
S
R
G
K
R
E
F
D
Site 10
S197
K
R
E
F
D
R
H
S
G
S
D
R
S
S
F
Site 11
S199
E
F
D
R
H
S
G
S
D
R
S
S
F
S
H
Site 12
S202
R
H
S
G
S
D
R
S
S
F
S
H
Y
S
G
Site 13
S203
H
S
G
S
D
R
S
S
F
S
H
Y
S
G
L
Site 14
S205
G
S
D
R
S
S
F
S
H
Y
S
G
L
K
H
Site 15
Y207
D
R
S
S
F
S
H
Y
S
G
L
K
H
E
D
Site 16
S208
R
S
S
F
S
H
Y
S
G
L
K
H
E
D
K
Site 17
S219
H
E
D
K
R
G
G
S
G
S
H
N
W
G
T
Site 18
S221
D
K
R
G
G
S
G
S
H
N
W
G
T
V
K
Site 19
T226
S
G
S
H
N
W
G
T
V
K
D
E
L
T
E
Site 20
T232
G
T
V
K
D
E
L
T
E
S
P
K
Y
I
Q
Site 21
S234
V
K
D
E
L
T
E
S
P
K
Y
I
Q
K
Q
Site 22
Y237
E
L
T
E
S
P
K
Y
I
Q
K
Q
I
S
Y
Site 23
S243
K
Y
I
Q
K
Q
I
S
Y
N
Y
S
D
L
D
Site 24
Y244
Y
I
Q
K
Q
I
S
Y
N
Y
S
D
L
D
Q
Site 25
Y246
Q
K
Q
I
S
Y
N
Y
S
D
L
D
Q
S
N
Site 26
S247
K
Q
I
S
Y
N
Y
S
D
L
D
Q
S
N
V
Site 27
S252
N
Y
S
D
L
D
Q
S
N
V
T
E
E
T
P
Site 28
T255
D
L
D
Q
S
N
V
T
E
E
T
P
E
G
E
Site 29
T258
Q
S
N
V
T
E
E
T
P
E
G
E
E
H
H
Site 30
S328
K
G
F
V
L
H
K
S
K
S
E
E
A
H
A
Site 31
S330
F
V
L
H
K
S
K
S
E
E
A
H
A
E
D
Site 32
S338
E
E
A
H
A
E
D
S
V
M
D
H
H
F
R
Site 33
T352
R
K
P
A
N
D
I
T
S
Q
L
E
I
N
F
Site 34
S353
K
P
A
N
D
I
T
S
Q
L
E
I
N
F
G
Site 35
S386
G
G
R
P
N
R
G
S
R
T
D
K
S
S
A
Site 36
T388
R
P
N
R
G
S
R
T
D
K
S
S
A
S
A
Site 37
S391
R
G
S
R
T
D
K
S
S
A
S
A
P
D
V
Site 38
S392
G
S
R
T
D
K
S
S
A
S
A
P
D
V
D
Site 39
S394
R
T
D
K
S
S
A
S
A
P
D
V
D
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation