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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NETO2
Full Name:
Neuropilin and tolloid-like protein 2
Alias:
brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains 2; BTCL2; FLJ10430; NEOT2; neuropilin (NRP) and tolloid (TLL)-like 2
Type:
Membrane protein, integral
Mass (Da):
59393
Number AA:
525
UniProt ID:
Q8NC67
International Prot ID:
IPI00168341
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T51
Q
C
G
I
W
V
R
T
S
N
G
G
H
F
A
Site 2
S59
S
N
G
G
H
F
A
S
P
N
Y
P
D
S
Y
Site 3
S257
N
L
K
A
K
F
C
S
T
V
A
N
D
V
M
Site 4
T344
A
G
V
F
E
Q
I
T
K
T
H
G
T
I
I
Site 5
Y398
E
V
F
D
P
P
H
Y
E
L
F
S
L
R
D
Site 6
S402
P
P
H
Y
E
L
F
S
L
R
D
K
E
I
S
Site 7
S409
S
L
R
D
K
E
I
S
A
D
L
A
D
L
S
Site 8
S416
S
A
D
L
A
D
L
S
E
E
L
D
N
Y
Q
Site 9
Y422
L
S
E
E
L
D
N
Y
Q
K
M
R
R
S
S
Site 10
S428
N
Y
Q
K
M
R
R
S
S
T
A
S
R
C
I
Site 11
S429
Y
Q
K
M
R
R
S
S
T
A
S
R
C
I
H
Site 12
T430
Q
K
M
R
R
S
S
T
A
S
R
C
I
H
D
Site 13
S432
M
R
R
S
S
T
A
S
R
C
I
H
D
H
H
Site 14
S442
I
H
D
H
H
C
G
S
Q
A
S
S
V
K
Q
Site 15
S445
H
H
C
G
S
Q
A
S
S
V
K
Q
S
R
T
Site 16
S446
H
C
G
S
Q
A
S
S
V
K
Q
S
R
T
N
Site 17
S450
Q
A
S
S
V
K
Q
S
R
T
N
L
S
S
M
Site 18
T452
S
S
V
K
Q
S
R
T
N
L
S
S
M
E
L
Site 19
S455
K
Q
S
R
T
N
L
S
S
M
E
L
P
F
R
Site 20
S456
Q
S
R
T
N
L
S
S
M
E
L
P
F
R
N
Site 21
T473
A
Q
P
Q
P
M
K
T
F
N
S
T
F
K
K
Site 22
S476
Q
P
M
K
T
F
N
S
T
F
K
K
S
S
Y
Site 23
T477
P
M
K
T
F
N
S
T
F
K
K
S
S
Y
T
Site 24
S481
F
N
S
T
F
K
K
S
S
Y
T
F
K
Q
G
Site 25
Y483
S
T
F
K
K
S
S
Y
T
F
K
Q
G
H
E
Site 26
T484
T
F
K
K
S
S
Y
T
F
K
Q
G
H
E
C
Site 27
Y509
E
E
I
P
C
E
I
Y
V
R
G
R
E
D
S
Site 28
S516
Y
V
R
G
R
E
D
S
A
Q
A
S
I
S
I
Site 29
S520
R
E
D
S
A
Q
A
S
I
S
I
D
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation