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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NECAP1
Full Name:
Adaptin ear-binding coat-associated protein 1
Alias:
dkfzp566b183; mgc131900; necap endocytosis associated 1; necap1; necap1 protein; necp1
Type:
Mass (Da):
29740
Number AA:
275
UniProt ID:
Q8NC96
International Prot ID:
IPI00170916
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
GO:0005905
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006897
GO:0015031
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
C
V
K
P
D
V
S
V
Y
R
I
P
P
R
Site 2
Y20
V
K
P
D
V
S
V
Y
R
I
P
P
R
A
S
Site 3
S27
Y
R
I
P
P
R
A
S
N
R
G
Y
R
A
S
Site 4
Y31
P
R
A
S
N
R
G
Y
R
A
S
D
W
K
L
Site 5
S34
S
N
R
G
Y
R
A
S
D
W
K
L
D
Q
P
Site 6
T44
K
L
D
Q
P
D
W
T
G
R
L
R
I
T
S
Site 7
T50
W
T
G
R
L
R
I
T
S
K
G
K
T
A
Y
Site 8
S51
T
G
R
L
R
I
T
S
K
G
K
T
A
Y
I
Site 9
T55
R
I
T
S
K
G
K
T
A
Y
I
K
L
E
D
Site 10
S65
I
K
L
E
D
K
V
S
G
E
L
F
A
Q
A
Site 11
T84
Y
P
G
I
A
V
E
T
V
T
D
S
S
R
Y
Site 12
S88
A
V
E
T
V
T
D
S
S
R
Y
F
V
I
R
Site 13
Y91
T
V
T
D
S
S
R
Y
F
V
I
R
I
Q
D
Site 14
S134
F
K
W
V
K
Q
E
S
E
I
S
K
E
S
Q
Site 15
S137
V
K
Q
E
S
E
I
S
K
E
S
Q
E
M
D
Site 16
T178
G
G
A
S
K
P
R
T
A
R
G
G
G
L
S
Site 17
S185
T
A
R
G
G
G
L
S
L
L
P
P
P
P
G
Site 18
T196
P
P
P
G
G
K
V
T
I
P
P
P
S
S
S
Site 19
S201
K
V
T
I
P
P
P
S
S
S
V
A
I
S
N
Site 20
S207
P
S
S
S
V
A
I
S
N
H
V
T
P
P
P
Site 21
T211
V
A
I
S
N
H
V
T
P
P
P
I
P
K
S
Site 22
S218
T
P
P
P
I
P
K
S
N
H
G
G
S
D
A
Site 23
T239
D
S
P
A
P
V
T
T
P
A
P
T
P
V
S
Site 24
T243
P
V
T
T
P
A
P
T
P
V
S
V
S
N
D
Site 25
S246
T
P
A
P
T
P
V
S
V
S
N
D
L
W
G
Site 26
S256
N
D
L
W
G
D
F
S
T
A
S
S
S
V
P
Site 27
T257
D
L
W
G
D
F
S
T
A
S
S
S
V
P
N
Site 28
S260
G
D
F
S
T
A
S
S
S
V
P
N
Q
A
P
Site 29
S261
D
F
S
T
A
S
S
S
V
P
N
Q
A
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation