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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTMR14
Full Name:
Myotubularin-related protein 14
Alias:
C3orf29; CC029; egg-derived tyrosine phosphatase; FLJ22405; FLJ90311; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; Jumpy; MTMRE; myotubularin related protein 14; NS5ATP4ABP1
Type:
EC 3.1.3.-; Phosphatase, lipid
Mass (Da):
72203
Number AA:
650
UniProt ID:
Q8NCE2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0048471
GO:0001726
Uniprot
OncoNet
Molecular Function:
GO:0004438
GO:0004725
PhosphoSite+
KinaseNET
Biological Process:
GO:0016311
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
A
A
A
S
A
G
S
S
A
S
S
G
N
Q
Site 2
S16
A
A
A
S
A
G
S
S
A
S
S
G
N
Q
P
Site 3
S19
S
A
G
S
S
A
S
S
G
N
Q
P
P
Q
E
Site 4
T39
L
L
E
E
F
S
R
T
Q
Y
R
A
K
D
G
Site 5
Y41
E
E
F
S
R
T
Q
Y
R
A
K
D
G
S
G
Site 6
S47
Q
Y
R
A
K
D
G
S
G
T
G
G
S
K
V
Site 7
S52
D
G
S
G
T
G
G
S
K
V
E
R
I
E
K
Site 8
Y94
R
H
I
V
F
L
E
Y
E
S
S
E
K
E
K
Site 9
S97
V
F
L
E
Y
E
S
S
E
K
E
K
D
T
F
Site 10
T103
S
S
E
K
E
K
D
T
F
E
S
T
V
Q
V
Site 11
S106
K
E
K
D
T
F
E
S
T
V
Q
V
S
K
L
Site 12
T107
E
K
D
T
F
E
S
T
V
Q
V
S
K
L
Q
Site 13
S144
K
G
K
H
I
C
R
S
A
T
L
A
G
W
G
Site 14
T146
K
H
I
C
R
S
A
T
L
A
G
W
G
E
L
Site 15
Y154
L
A
G
W
G
E
L
Y
G
R
S
G
Y
N
Y
Site 16
Y159
E
L
Y
G
R
S
G
Y
N
Y
F
F
S
G
G
Site 17
Y161
Y
G
R
S
G
Y
N
Y
F
F
S
G
G
A
D
Site 18
T178
W
A
D
V
E
D
V
T
E
E
D
C
A
L
R
Site 19
S186
E
E
D
C
A
L
R
S
G
D
T
H
L
F
D
Site 20
Y198
L
F
D
K
V
R
G
Y
D
I
K
L
L
R
Y
Site 21
Y210
L
R
Y
L
S
V
K
Y
I
C
D
L
M
V
E
Site 22
S230
F
G
M
N
V
T
S
S
E
K
V
D
K
A
Q
Site 23
Y239
K
V
D
K
A
Q
R
Y
A
D
F
T
L
L
S
Site 24
T243
A
Q
R
Y
A
D
F
T
L
L
S
I
P
Y
P
Site 25
Y258
G
C
E
F
F
K
E
Y
K
D
R
D
Y
M
A
Site 26
Y263
K
E
Y
K
D
R
D
Y
M
A
E
G
L
I
F
Site 27
Y276
I
F
N
W
K
Q
D
Y
V
D
A
P
L
S
I
Site 28
S282
D
Y
V
D
A
P
L
S
I
P
D
F
L
T
H
Site 29
S316
N
Y
L
K
L
L
L
S
L
V
N
S
D
D
D
Site 30
S384
H
M
L
V
D
R
L
S
K
G
E
E
I
F
F
Site 31
S402
N
F
L
K
H
I
T
S
E
E
F
S
A
L
K
Site 32
S406
H
I
T
S
E
E
F
S
A
L
K
T
Q
R
R
Site 33
T410
E
E
F
S
A
L
K
T
Q
R
R
K
S
L
P
Site 34
S415
L
K
T
Q
R
R
K
S
L
P
A
R
D
G
G
Site 35
S438
L
R
R
K
D
R
G
S
T
T
S
L
G
S
D
Site 36
T439
R
R
K
D
R
G
S
T
T
S
L
G
S
D
F
Site 37
T440
R
K
D
R
G
S
T
T
S
L
G
S
D
F
S
Site 38
S441
K
D
R
G
S
T
T
S
L
G
S
D
F
S
L
Site 39
S447
T
S
L
G
S
D
F
S
L
V
M
E
S
S
P
Site 40
S452
D
F
S
L
V
M
E
S
S
P
G
A
T
G
S
Site 41
S459
S
S
P
G
A
T
G
S
F
T
Y
E
A
V
E
Site 42
Y462
G
A
T
G
S
F
T
Y
E
A
V
E
L
V
P
Site 43
S481
T
Q
A
A
W
R
K
S
H
S
S
S
P
Q
S
Site 44
S483
A
A
W
R
K
S
H
S
S
S
P
Q
S
V
L
Site 45
S484
A
W
R
K
S
H
S
S
S
P
Q
S
V
L
W
Site 46
S485
W
R
K
S
H
S
S
S
P
Q
S
V
L
W
N
Site 47
S488
S
H
S
S
S
P
Q
S
V
L
W
N
R
P
Q
Site 48
S497
L
W
N
R
P
Q
P
S
E
D
R
L
P
S
Q
Site 49
S503
P
S
E
D
R
L
P
S
Q
Q
G
L
A
E
A
Site 50
S512
Q
G
L
A
E
A
R
S
S
S
S
S
S
S
N
Site 51
S513
G
L
A
E
A
R
S
S
S
S
S
S
S
N
H
Site 52
S514
L
A
E
A
R
S
S
S
S
S
S
S
N
H
S
Site 53
S515
A
E
A
R
S
S
S
S
S
S
S
N
H
S
D
Site 54
S516
E
A
R
S
S
S
S
S
S
S
N
H
S
D
N
Site 55
S517
A
R
S
S
S
S
S
S
S
N
H
S
D
N
F
Site 56
S518
R
S
S
S
S
S
S
S
N
H
S
D
N
F
F
Site 57
S521
S
S
S
S
S
N
H
S
D
N
F
F
R
M
G
Site 58
S529
D
N
F
F
R
M
G
S
S
P
L
E
V
P
K
Site 59
S530
N
F
F
R
M
G
S
S
P
L
E
V
P
K
P
Site 60
S539
L
E
V
P
K
P
R
S
V
D
H
P
L
P
G
Site 61
S547
V
D
H
P
L
P
G
S
S
L
S
T
D
Y
G
Site 62
S548
D
H
P
L
P
G
S
S
L
S
T
D
Y
G
S
Site 63
S550
P
L
P
G
S
S
L
S
T
D
Y
G
S
W
Q
Site 64
T551
L
P
G
S
S
L
S
T
D
Y
G
S
W
Q
M
Site 65
Y553
G
S
S
L
S
T
D
Y
G
S
W
Q
M
V
T
Site 66
T573
Q
E
R
A
V
L
H
T
D
S
S
L
P
F
S
Site 67
S575
R
A
V
L
H
T
D
S
S
L
P
F
S
F
P
Site 68
S576
A
V
L
H
T
D
S
S
L
P
F
S
F
P
D
Site 69
S580
T
D
S
S
L
P
F
S
F
P
D
E
L
P
N
Site 70
S595
S
C
L
L
A
A
L
S
D
R
E
T
R
L
Q
Site 71
T599
A
A
L
S
D
R
E
T
R
L
Q
E
V
R
S
Site 72
S624
G
L
R
A
V
A
P
S
P
S
G
A
I
G
G
Site 73
S644
A
R
G
V
G
L
R
S
I
S
S
N
A
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation