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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DAGLB
Full Name:
Sn1-specific diacylglycerol lipase beta
Alias:
DAGLBETA; DGLB; DGL-beta; Diacylglycerol lipase, beta; KCCR13L
Type:
EC 3.1.1.-; Lipase
Mass (Da):
73732
Number AA:
672
UniProt ID:
Q8NCG7
International Prot ID:
IPI00385987
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004806
GO:0004806
PhosphoSite+
KinaseNET
Biological Process:
GO:0016042
GO:0008152
GO:0009056
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
G
R
R
W
A
I
A
S
D
D
L
V
F
P
G
Site 2
T84
M
C
V
S
M
R
G
T
I
C
N
P
G
P
R
Site 3
S93
C
N
P
G
P
R
K
S
M
S
K
L
L
Y
I
Site 4
S95
P
G
P
R
K
S
M
S
K
L
L
Y
I
R
L
Site 5
Y165
L
G
G
K
M
A
P
Y
S
S
A
G
P
S
H
Site 6
S166
G
G
K
M
A
P
Y
S
S
A
G
P
S
H
L
Site 7
S167
G
K
M
A
P
Y
S
S
A
G
P
S
H
L
D
Site 8
S171
P
Y
S
S
A
G
P
S
H
L
D
S
H
D
S
Site 9
S175
A
G
P
S
H
L
D
S
H
D
S
S
Q
L
L
Site 10
S178
S
H
L
D
S
H
D
S
S
Q
L
L
N
G
L
Site 11
S179
H
L
D
S
H
D
S
S
Q
L
L
N
G
L
K
Site 12
T187
Q
L
L
N
G
L
K
T
A
A
T
S
V
W
E
Site 13
T190
N
G
L
K
T
A
A
T
S
V
W
E
T
R
I
Site 14
T210
C
I
G
K
D
D
H
T
R
V
A
F
S
S
T
Site 15
S216
H
T
R
V
A
F
S
S
T
A
E
L
F
S
T
Site 16
S222
S
S
T
A
E
L
F
S
T
Y
F
S
D
T
D
Site 17
T223
S
T
A
E
L
F
S
T
Y
F
S
D
T
D
L
Site 18
S226
E
L
F
S
T
Y
F
S
D
T
D
L
V
P
S
Site 19
Y294
A
A
Y
G
W
P
L
Y
I
Y
R
N
P
L
T
Site 20
Y296
Y
G
W
P
L
Y
I
Y
R
N
P
L
T
G
L
Site 21
T301
Y
I
Y
R
N
P
L
T
G
L
C
R
I
G
G
Site 22
T315
G
D
C
C
R
S
R
T
T
D
Y
D
L
V
G
Site 23
T316
D
C
C
R
S
R
T
T
D
Y
D
L
V
G
G
Site 24
Y318
C
R
S
R
T
T
D
Y
D
L
V
G
G
D
Q
Site 25
T336
H
F
G
S
I
L
H
T
T
G
L
Q
Y
R
D
Site 26
S368
A
L
D
H
R
K
E
S
V
V
V
A
V
R
G
Site 27
S378
V
A
V
R
G
T
M
S
L
Q
D
V
L
T
D
Site 28
T384
M
S
L
Q
D
V
L
T
D
L
S
A
E
S
E
Site 29
S387
Q
D
V
L
T
D
L
S
A
E
S
E
V
L
D
Site 30
S409
R
L
A
H
K
G
I
S
Q
A
A
R
Y
V
Y
Site 31
Y414
G
I
S
Q
A
A
R
Y
V
Y
Q
R
L
I
N
Site 32
Y416
S
Q
A
A
R
Y
V
Y
Q
R
L
I
N
D
G
Site 33
Y460
A
T
M
L
R
A
A
Y
P
Q
V
R
C
Y
A
Site 34
Y466
A
Y
P
Q
V
R
C
Y
A
F
S
P
P
R
G
Site 35
S469
Q
V
R
C
Y
A
F
S
P
P
R
G
L
W
S
Site 36
S476
S
P
P
R
G
L
W
S
K
A
L
Q
E
Y
S
Site 37
S483
S
K
A
L
Q
E
Y
S
Q
S
F
I
V
S
L
Site 38
S501
K
D
V
I
P
R
L
S
V
T
N
L
E
D
L
Site 39
Y524
A
H
C
N
K
P
K
Y
K
I
L
L
H
G
L
Site 40
T556
G
G
D
Q
E
V
L
T
Q
P
L
L
G
E
Q
Site 41
S564
Q
P
L
L
G
E
Q
S
L
L
T
R
W
S
P
Site 42
S570
Q
S
L
L
T
R
W
S
P
A
Y
S
F
S
S
Site 43
Y573
L
T
R
W
S
P
A
Y
S
F
S
S
D
S
P
Site 44
S574
T
R
W
S
P
A
Y
S
F
S
S
D
S
P
L
Site 45
S576
W
S
P
A
Y
S
F
S
S
D
S
P
L
D
S
Site 46
S577
S
P
A
Y
S
F
S
S
D
S
P
L
D
S
S
Site 47
S579
A
Y
S
F
S
S
D
S
P
L
D
S
S
P
K
Site 48
S583
S
S
D
S
P
L
D
S
S
P
K
Y
P
P
L
Site 49
S584
S
D
S
P
L
D
S
S
P
K
Y
P
P
L
Y
Site 50
Y587
P
L
D
S
S
P
K
Y
P
P
L
Y
P
P
G
Site 51
Y591
S
P
K
Y
P
P
L
Y
P
P
G
R
I
I
H
Site 52
S605
H
L
Q
E
E
G
A
S
G
R
F
G
C
C
S
Site 53
S612
S
G
R
F
G
C
C
S
A
A
H
Y
S
A
K
Site 54
Y616
G
C
C
S
A
A
H
Y
S
A
K
W
S
H
E
Site 55
S621
A
H
Y
S
A
K
W
S
H
E
A
E
F
S
K
Site 56
S653
R
A
L
D
S
V
V
S
D
R
A
A
C
V
S
Site 57
S660
S
D
R
A
A
C
V
S
C
P
A
Q
G
V
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation