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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAD2
Full Name:
Adenosine deaminase domain-containing protein 2
Alias:
Testis nuclear RNA-binding protein-like
Type:
Mass (Da):
61755
Number AA:
583
UniProt ID:
Q8NCV1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
Q
G
A
D
D
D
G
S
R
R
K
P
R
L
A
Site 2
S22
R
K
P
R
L
A
A
S
L
Q
I
S
P
Q
P
Site 3
S26
L
A
A
S
L
Q
I
S
P
Q
P
R
P
W
R
Site 4
T51
G
P
A
P
A
P
A
T
Y
R
A
E
G
G
W
Site 5
Y52
P
A
P
A
P
A
T
Y
R
A
E
G
G
W
P
Site 6
S62
E
G
G
W
P
Q
V
S
V
L
R
D
S
G
P
Site 7
S67
Q
V
S
V
L
R
D
S
G
P
G
A
G
A
G
Site 8
S105
P
V
P
P
A
G
L
S
L
P
L
K
D
P
P
Site 9
S114
P
L
K
D
P
P
A
S
Q
A
V
S
L
L
T
Site 10
T165
A
G
T
A
N
S
K
T
E
A
K
Q
Q
A
A
Site 11
S181
S
A
L
C
Y
I
R
S
Q
L
E
N
P
E
S
Site 12
S188
S
Q
L
E
N
P
E
S
P
Q
T
S
S
R
P
Site 13
T191
E
N
P
E
S
P
Q
T
S
S
R
P
P
L
A
Site 14
S192
N
P
E
S
P
Q
T
S
S
R
P
P
L
A
P
Site 15
S193
P
E
S
P
Q
T
S
S
R
P
P
L
A
P
L
Site 16
S201
R
P
P
L
A
P
L
S
V
E
N
I
L
T
H
Site 17
T207
L
S
V
E
N
I
L
T
H
E
Q
R
C
A
A
Site 18
S228
D
L
L
L
D
E
R
S
P
Y
W
A
C
K
G
Site 19
Y230
L
L
D
E
R
S
P
Y
W
A
C
K
G
T
V
Site 20
T236
P
Y
W
A
C
K
G
T
V
A
G
V
I
L
E
Site 21
Y257
R
G
H
V
K
E
I
Y
K
L
V
A
L
G
T
Site 22
S315
G
P
K
G
K
E
Q
S
V
L
A
P
Q
P
G
Site 23
T328
P
G
P
G
P
P
F
T
L
K
P
R
V
F
L
Site 24
Y338
P
R
V
F
L
H
L
Y
I
S
N
T
P
K
G
Site 25
T342
L
H
L
Y
I
S
N
T
P
K
G
A
A
R
D
Site 26
Y351
K
G
A
A
R
D
I
Y
L
P
P
T
S
E
G
Site 27
T355
R
D
I
Y
L
P
P
T
S
E
G
G
L
P
H
Site 28
S356
D
I
Y
L
P
P
T
S
E
G
G
L
P
H
S
Site 29
S363
S
E
G
G
L
P
H
S
P
P
M
R
L
Q
A
Site 30
S395
D
T
H
V
G
C
L
S
A
S
D
K
L
A
R
Site 31
T436
D
S
C
H
D
P
P
T
L
S
R
A
I
H
T
Site 32
S438
C
H
D
P
P
T
L
S
R
A
I
H
T
R
P
Site 33
S475
A
G
P
P
V
A
P
S
E
P
T
P
D
T
C
Site 34
T478
P
V
A
P
S
E
P
T
P
D
T
C
R
G
L
Site 35
T481
P
S
E
P
T
P
D
T
C
R
G
L
S
L
N
Site 36
S486
P
D
T
C
R
G
L
S
L
N
W
S
L
G
D
Site 37
S490
R
G
L
S
L
N
W
S
L
G
D
P
G
I
E
Site 38
S516
N
A
A
L
G
P
P
S
R
L
C
K
A
S
F
Site 39
S522
P
S
R
L
C
K
A
S
F
L
R
A
F
H
Q
Site 40
S561
Q
E
A
R
R
Q
L
S
L
L
L
D
Q
Q
G
Site 41
S574
Q
G
L
G
A
W
P
S
K
P
L
V
G
K
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation