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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HEATR7A
Full Name:
HEAT repeat-containing protein 7A
Alias:
Type:
Mass (Da):
181249
Number AA:
1641
UniProt ID:
Q8NDA8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
E
S
S
M
K
K
L
Site 2
T18
S
T
L
L
D
A
I
T
D
K
D
P
L
V
Q
Site 3
Y50
T
L
R
A
C
E
E
Y
L
R
Q
H
D
K
L
Site 4
S74
R
A
M
E
R
V
L
S
S
R
A
S
E
L
D
Site 5
S75
A
M
E
R
V
L
S
S
R
A
S
E
L
D
K
Site 6
S78
R
V
L
S
S
R
A
S
E
L
D
K
D
T
A
Site 7
S94
T
I
I
L
L
A
S
S
E
M
T
K
T
K
D
Site 8
T97
L
L
A
S
S
E
M
T
K
T
K
D
L
V
W
Site 9
T99
A
S
S
E
M
T
K
T
K
D
L
V
W
D
W
Site 10
S193
C
S
A
L
Q
R
F
S
E
G
A
L
E
Y
L
Site 11
T210
L
D
R
A
P
D
P
T
V
R
K
D
A
F
A
Site 12
T218
V
R
K
D
A
F
A
T
D
I
F
S
A
Y
D
Site 13
S234
L
F
H
Q
W
L
Q
S
R
E
A
K
L
R
L
Site 14
S251
V
E
A
L
G
P
M
S
H
L
L
P
S
E
R
Site 15
S256
P
M
S
H
L
L
P
S
E
R
L
E
E
Q
L
Site 16
T280
L
Y
K
K
H
A
E
T
F
Y
L
S
K
S
L
Site 17
Y282
K
K
H
A
E
T
F
Y
L
S
K
S
L
G
Q
Site 18
S286
E
T
F
Y
L
S
K
S
L
G
Q
I
L
E
A
Site 19
S330
S
S
S
P
L
V
M
S
N
Q
K
E
V
L
R
Site 20
T360
F
L
L
P
R
L
D
T
S
N
E
R
T
R
V
Site 21
S361
L
L
P
R
L
D
T
S
N
E
R
T
R
V
G
Site 22
T365
L
D
T
S
N
E
R
T
R
V
G
T
L
Q
V
Site 23
T369
N
E
R
T
R
V
G
T
L
Q
V
V
R
H
V
Site 24
T402
M
R
L
P
L
L
D
T
N
S
K
V
K
R
A
Site 25
Y422
S
A
M
A
H
H
G
Y
L
E
Q
P
G
G
E
Site 26
S454
P
E
K
P
G
P
G
S
K
D
P
K
A
D
S
Site 27
S461
S
K
D
P
K
A
D
S
V
R
A
I
S
V
R
Site 28
T475
R
T
L
Y
L
V
S
T
T
V
D
R
M
S
H
Site 29
S532
I
Q
Y
D
A
H
A
S
L
P
S
P
Y
A
V
Site 30
S535
D
A
H
A
S
L
P
S
P
Y
A
V
T
G
R
Site 31
S549
R
L
L
V
V
S
S
S
P
Y
L
G
D
G
R
Site 32
T594
L
G
Y
L
D
E
H
T
E
E
T
L
P
Q
E
Site 33
Y638
L
C
R
Q
L
P
C
Y
D
E
A
P
Q
E
K
Site 34
Y649
P
Q
E
K
N
F
L
Y
K
C
I
G
T
T
L
Site 35
S661
T
T
L
G
A
A
S
S
K
E
V
V
R
K
H
Site 36
T675
H
L
Q
E
L
L
E
T
A
R
Y
Q
E
E
A
Site 37
Y678
E
L
L
E
T
A
R
Y
Q
E
E
A
E
R
E
Site 38
T702
A
I
S
H
L
E
D
T
L
A
Q
L
E
D
F
Site 39
S729
L
N
I
F
K
D
R
S
E
N
E
V
E
K
V
Site 40
S806
V
S
R
A
I
C
S
S
T
Q
A
G
S
F
H
Site 41
T807
S
R
A
I
C
S
S
T
Q
A
G
S
F
H
F
Site 42
S811
C
S
S
T
Q
A
G
S
F
H
F
T
R
K
A
Site 43
T815
Q
A
G
S
F
H
F
T
R
K
A
E
L
V
A
Site 44
S835
I
R
A
E
P
P
D
S
L
R
T
P
I
R
K
Site 45
T838
E
P
P
D
S
L
R
T
P
I
R
K
K
A
M
Site 46
S891
E
D
G
G
C
Q
K
S
L
Y
L
E
T
L
H
Site 47
T905
H
A
L
E
D
L
L
T
S
L
L
Q
R
N
M
Site 48
T913
S
L
L
Q
R
N
M
T
P
Q
G
L
Q
I
M
Site 49
S925
Q
I
M
I
E
H
L
S
P
W
I
K
S
P
R
Site 50
S930
H
L
S
P
W
I
K
S
P
R
G
H
E
R
A
Site 51
Y1008
Y
E
G
F
S
R
D
Y
R
D
D
V
A
E
R
Site 52
S1097
E
K
V
P
E
I
V
S
V
L
R
S
K
L
Q
Site 53
S1101
E
I
V
S
V
L
R
S
K
L
Q
E
A
Q
G
Site 54
S1143
G
S
P
L
P
L
D
S
H
T
C
M
L
W
R
Site 55
S1171
G
L
L
L
E
K
M
S
R
D
V
P
F
K
E
Site 56
T1193
R
T
P
D
R
V
A
T
L
L
P
L
S
A
T
Site 57
S1252
A
Q
E
R
R
G
A
S
P
A
L
A
T
R
N
Site 58
S1264
T
R
N
L
E
P
C
S
S
A
V
D
T
L
R
Site 59
S1265
R
N
L
E
P
C
S
S
A
V
D
T
L
R
S
Site 60
S1272
S
A
V
D
T
L
R
S
M
L
L
R
S
G
S
Site 61
S1279
S
M
L
L
R
S
G
S
E
D
V
V
Q
R
M
Site 62
T1297
G
G
W
E
L
L
R
T
S
A
G
H
E
E
G
Site 63
S1298
G
W
E
L
L
R
T
S
A
G
H
E
E
G
A
Site 64
T1306
A
G
H
E
E
G
A
T
R
L
A
R
A
M
A
Site 65
S1332
K
T
L
A
C
T
H
S
S
A
Y
E
N
Q
R
Site 66
T1341
A
Y
E
N
Q
R
V
T
T
T
A
F
L
A
E
Site 67
T1342
Y
E
N
Q
R
V
T
T
T
A
F
L
A
E
L
Site 68
S1367
L
L
D
S
L
L
E
S
L
A
A
R
Q
K
D
Site 69
S1378
R
Q
K
D
T
C
A
S
V
R
R
L
V
L
R
Site 70
S1392
R
G
L
A
N
L
A
S
G
C
P
D
K
V
R
Site 71
T1400
G
C
P
D
K
V
R
T
H
G
P
Q
L
L
T
Site 72
S1421
D
D
G
D
N
P
H
S
P
V
A
L
E
A
M
Site 73
S1440
R
L
V
H
L
V
E
S
W
D
L
R
S
G
L
Site 74
S1460
R
I
R
P
F
F
D
S
E
K
M
E
F
R
T
Site 75
S1469
K
M
E
F
R
T
A
S
I
R
L
F
G
H
L
Site 76
S1598
T
G
F
L
V
L
H
S
E
P
R
Q
Q
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation