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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PAPD5
Full Name:
PAP-associated domain-containing protein 5
Alias:
flj40270; pap associated domain containing 5; papd5; trf4-2
Type:
Transferase; EC 2.7.7.-
Mass (Da):
63267
Number AA:
572
UniProt ID:
Q8NDF8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003887
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0051301
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
A
W
A
R
R
A
G
S
S
A
S
S
P
P
S
Site 2
S46
W
A
R
R
A
G
S
S
A
S
S
P
P
S
A
Site 3
S48
R
R
A
G
S
S
A
S
S
P
P
S
A
S
S
Site 4
S49
R
A
G
S
S
A
S
S
P
P
S
A
S
S
S
Site 5
S52
S
S
A
S
S
P
P
S
A
S
S
S
P
H
P
Site 6
S54
A
S
S
P
P
S
A
S
S
S
P
H
P
S
A
Site 7
S55
S
S
P
P
S
A
S
S
S
P
H
P
S
A
A
Site 8
S56
S
P
P
S
A
S
S
S
P
H
P
S
A
A
V
Site 9
S60
A
S
S
S
P
H
P
S
A
A
V
P
A
A
D
Site 10
S71
P
A
A
D
P
A
D
S
A
S
G
S
S
N
K
Site 11
S73
A
D
P
A
D
S
A
S
G
S
S
N
K
R
K
Site 12
S75
P
A
D
S
A
S
G
S
S
N
K
R
K
R
D
Site 13
S86
R
K
R
D
N
K
A
S
G
G
R
A
A
G
G
Site 14
S104
D
G
G
G
V
V
Y
S
G
T
P
W
K
R
R
Site 15
T106
G
G
V
V
Y
S
G
T
P
W
K
R
R
N
Y
Site 16
Y113
T
P
W
K
R
R
N
Y
N
Q
G
V
V
G
L
Site 17
Y128
H
E
E
I
S
D
F
Y
E
Y
M
S
P
R
P
Site 18
Y130
E
I
S
D
F
Y
E
Y
M
S
P
R
P
E
E
Site 19
S132
S
D
F
Y
E
Y
M
S
P
R
P
E
E
E
K
Site 20
S150
E
V
V
N
R
I
E
S
V
I
K
E
L
W
P
Site 21
Y172
G
S
F
K
T
G
L
Y
L
P
T
S
D
I
D
Site 22
S208
H
K
V
A
D
E
D
S
V
K
V
L
D
K
A
Site 23
S234
T
E
V
K
V
D
I
S
F
N
V
Q
N
G
V
Site 24
T251
A
D
L
I
K
D
F
T
K
K
Y
P
V
L
P
Site 25
Y326
L
Y
G
R
H
F
N
Y
L
K
T
G
I
R
I
Site 26
T329
R
H
F
N
Y
L
K
T
G
I
R
I
K
D
G
Site 27
S338
I
R
I
K
D
G
G
S
Y
V
A
K
D
E
V
Site 28
Y339
R
I
K
D
G
G
S
Y
V
A
K
D
E
V
Q
Site 29
Y353
Q
K
N
M
L
D
G
Y
R
P
S
M
L
Y
I
Site 30
S356
M
L
D
G
Y
R
P
S
M
L
Y
I
E
D
P
Site 31
Y359
G
Y
R
P
S
M
L
Y
I
E
D
P
L
Q
P
Site 32
S373
P
G
N
D
V
G
R
S
S
Y
G
A
M
Q
V
Site 33
S374
G
N
D
V
G
R
S
S
Y
G
A
M
Q
V
K
Site 34
Y375
N
D
V
G
R
S
S
Y
G
A
M
Q
V
K
Q
Site 35
Y401
A
V
S
P
I
A
K
Y
Y
P
N
N
E
T
E
Site 36
Y402
V
S
P
I
A
K
Y
Y
P
N
N
E
T
E
S
Site 37
T418
L
G
R
I
I
R
V
T
D
E
V
A
T
Y
R
Site 38
T423
R
V
T
D
E
V
A
T
Y
R
D
W
I
S
K
Site 39
Y424
V
T
D
E
V
A
T
Y
R
D
W
I
S
K
Q
Site 40
S441
L
K
N
R
P
E
P
S
C
N
G
P
V
S
S
Site 41
S447
P
S
C
N
G
P
V
S
S
S
S
A
T
Q
S
Site 42
S448
S
C
N
G
P
V
S
S
S
S
A
T
Q
S
S
Site 43
S449
C
N
G
P
V
S
S
S
S
A
T
Q
S
S
S
Site 44
S450
N
G
P
V
S
S
S
S
A
T
Q
S
S
S
S
Site 45
T452
P
V
S
S
S
S
A
T
Q
S
S
S
S
D
V
Site 46
S454
S
S
S
S
A
T
Q
S
S
S
S
D
V
D
S
Site 47
S455
S
S
S
A
T
Q
S
S
S
S
D
V
D
S
D
Site 48
S456
S
S
A
T
Q
S
S
S
S
D
V
D
S
D
A
Site 49
S457
S
A
T
Q
S
S
S
S
D
V
D
S
D
A
T
Site 50
S461
S
S
S
S
D
V
D
S
D
A
T
P
C
K
T
Site 51
T464
S
D
V
D
S
D
A
T
P
C
K
T
P
K
Q
Site 52
T468
S
D
A
T
P
C
K
T
P
K
Q
L
L
C
R
Site 53
S477
K
Q
L
L
C
R
P
S
T
G
N
R
V
G
S
Site 54
T478
Q
L
L
C
R
P
S
T
G
N
R
V
G
S
Q
Site 55
S484
S
T
G
N
R
V
G
S
Q
D
V
S
L
E
S
Site 56
S488
R
V
G
S
Q
D
V
S
L
E
S
S
Q
A
V
Site 57
S492
Q
D
V
S
L
E
S
S
Q
A
V
G
K
M
Q
Site 58
T503
G
K
M
Q
S
T
Q
T
T
N
T
S
N
S
T
Site 59
T504
K
M
Q
S
T
Q
T
T
N
T
S
N
S
T
N
Site 60
S507
S
T
Q
T
T
N
T
S
N
S
T
N
K
S
Q
Site 61
S509
Q
T
T
N
T
S
N
S
T
N
K
S
Q
H
G
Site 62
S513
T
S
N
S
T
N
K
S
Q
H
G
S
A
R
L
Site 63
S517
T
N
K
S
Q
H
G
S
A
R
L
F
R
S
S
Site 64
S523
G
S
A
R
L
F
R
S
S
S
K
G
F
Q
G
Site 65
S524
S
A
R
L
F
R
S
S
S
K
G
F
Q
G
T
Site 66
S525
A
R
L
F
R
S
S
S
K
G
F
Q
G
T
T
Site 67
T531
S
S
K
G
F
Q
G
T
T
Q
T
S
H
G
S
Site 68
T532
S
K
G
F
Q
G
T
T
Q
T
S
H
G
S
L
Site 69
T534
G
F
Q
G
T
T
Q
T
S
H
G
S
L
M
T
Site 70
Y553
Q
G
K
S
N
N
Q
Y
Y
H
G
K
K
R
K
Site 71
Y554
G
K
S
N
N
Q
Y
Y
H
G
K
K
R
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation