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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGBL5
Full Name:
Cytosolic carboxypeptidase-like protein 5
Alias:
ATP/GTP-binding protein-like 5
Type:
Mass (Da):
97534
Number AA:
886
UniProt ID:
Q8NDL9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
R
C
G
G
L
L
F
S
S
R
F
D
S
G
N
Site 2
S16
L
F
S
S
R
F
D
S
G
N
L
A
H
V
E
Site 3
S27
A
H
V
E
K
V
E
S
L
S
S
D
G
E
G
Site 4
S29
V
E
K
V
E
S
L
S
S
D
G
E
G
V
G
Site 5
S30
E
K
V
E
S
L
S
S
D
G
E
G
V
G
G
Site 6
S44
G
G
A
S
A
L
T
S
G
I
A
S
S
P
D
Site 7
S48
A
L
T
S
G
I
A
S
S
P
D
Y
E
F
N
Site 8
S49
L
T
S
G
I
A
S
S
P
D
Y
E
F
N
V
Site 9
Y52
G
I
A
S
S
P
D
Y
E
F
N
V
W
T
R
Site 10
Y76
N
G
N
R
S
W
F
Y
F
S
V
R
G
G
M
Site 11
S103
N
K
Q
S
K
L
Y
S
Q
G
M
A
P
F
V
Site 12
T127
E
R
I
R
D
R
P
T
F
E
M
T
E
T
Q
Site 13
T181
R
F
P
E
N
H
P
T
H
S
S
P
L
D
T
Site 14
S184
E
N
H
P
T
H
S
S
P
L
D
T
I
Y
Y
Site 15
T188
T
H
S
S
P
L
D
T
I
Y
Y
H
R
E
L
Site 16
Y190
S
S
P
L
D
T
I
Y
Y
H
R
E
L
L
C
Site 17
Y191
S
P
L
D
T
I
Y
Y
H
R
E
L
L
C
Y
Site 18
Y198
Y
H
R
E
L
L
C
Y
S
L
D
G
L
R
V
Site 19
T211
R
V
D
L
L
T
I
T
S
C
H
G
L
R
E
Site 20
T231
L
E
Q
L
F
P
D
T
S
T
P
R
P
F
R
Site 21
S232
E
Q
L
F
P
D
T
S
T
P
R
P
F
R
F
Site 22
T233
Q
L
F
P
D
T
S
T
P
R
P
F
R
F
A
Site 23
S248
G
K
R
I
F
F
L
S
S
R
V
H
P
G
E
Site 24
S249
K
R
I
F
F
L
S
S
R
V
H
P
G
E
T
Site 25
T256
S
R
V
H
P
G
E
T
P
S
S
F
V
F
N
Site 26
S258
V
H
P
G
E
T
P
S
S
F
V
F
N
G
F
Site 27
S259
H
P
G
E
T
P
S
S
F
V
F
N
G
F
L
Site 28
T279
P
D
D
P
R
A
Q
T
L
R
R
L
F
V
F
Site 29
Y302
D
G
V
V
R
G
H
Y
R
T
D
S
R
G
V
Site 30
T304
V
V
R
G
H
Y
R
T
D
S
R
G
V
N
L
Site 31
S306
R
G
H
Y
R
T
D
S
R
G
V
N
L
N
R
Site 32
Y315
G
V
N
L
N
R
Q
Y
L
K
P
D
A
V
L
Site 33
S340
L
L
Y
H
H
V
H
S
R
L
N
S
Q
S
S
Site 34
S344
H
V
H
S
R
L
N
S
Q
S
S
S
E
H
Q
Site 35
S346
H
S
R
L
N
S
Q
S
S
S
E
H
Q
P
S
Site 36
S347
S
R
L
N
S
Q
S
S
S
E
H
Q
P
S
S
Site 37
S348
R
L
N
S
Q
S
S
S
E
H
Q
P
S
S
C
Site 38
S353
S
S
S
E
H
Q
P
S
S
C
L
P
P
D
A
Site 39
S354
S
S
E
H
Q
P
S
S
C
L
P
P
D
A
P
Site 40
S363
L
P
P
D
A
P
V
S
D
L
E
K
A
N
N
Site 41
T419
L
E
E
S
A
P
D
T
I
P
P
K
E
S
G
Site 42
Y429
P
K
E
S
G
V
A
Y
Y
V
D
L
H
G
H
Site 43
Y430
K
E
S
G
V
A
Y
Y
V
D
L
H
G
H
A
Site 44
Y445
S
K
R
G
C
F
M
Y
G
N
S
F
S
D
E
Site 45
S448
G
C
F
M
Y
G
N
S
F
S
D
E
S
T
Q
Site 46
S450
F
M
Y
G
N
S
F
S
D
E
S
T
Q
V
E
Site 47
S453
G
N
S
F
S
D
E
S
T
Q
V
E
N
M
L
Site 48
T454
N
S
F
S
D
E
S
T
Q
V
E
N
M
L
Y
Site 49
Y461
T
Q
V
E
N
M
L
Y
P
K
L
I
S
L
N
Site 50
S469
P
K
L
I
S
L
N
S
A
H
F
D
F
Q
G
Site 51
Y485
N
F
S
E
K
N
M
Y
A
R
D
R
R
D
G
Site 52
S494
R
D
R
R
D
G
Q
S
K
E
G
S
G
R
V
Site 53
S498
D
G
Q
S
K
E
G
S
G
R
V
A
I
Y
K
Site 54
T514
S
G
I
I
H
S
Y
T
L
E
C
N
Y
N
T
Site 55
Y519
S
Y
T
L
E
C
N
Y
N
T
G
R
S
V
N
Site 56
S524
C
N
Y
N
T
G
R
S
V
N
S
I
P
A
A
Site 57
S539
C
H
D
N
G
R
A
S
P
P
P
P
P
A
F
Site 58
S548
P
P
P
P
A
F
P
S
R
Y
T
V
E
L
F
Site 59
T551
P
A
F
P
S
R
Y
T
V
E
L
F
E
Q
V
Site 60
S581
P
W
P
R
I
V
L
S
E
H
S
S
L
T
N
Site 61
S600
M
L
K
H
V
R
N
S
R
G
L
S
S
T
L
Site 62
S604
V
R
N
S
R
G
L
S
S
T
L
N
V
G
V
Site 63
T606
N
S
R
G
L
S
S
T
L
N
V
G
V
N
K
Site 64
T619
N
K
K
R
G
L
R
T
P
P
K
S
H
N
G
Site 65
S623
G
L
R
T
P
P
K
S
H
N
G
L
P
V
S
Site 66
S630
S
H
N
G
L
P
V
S
C
S
E
N
T
L
S
Site 67
S632
N
G
L
P
V
S
C
S
E
N
T
L
S
R
A
Site 68
T635
P
V
S
C
S
E
N
T
L
S
R
A
R
S
F
Site 69
S637
S
C
S
E
N
T
L
S
R
A
R
S
F
S
T
Site 70
S641
N
T
L
S
R
A
R
S
F
S
T
G
T
S
A
Site 71
S643
L
S
R
A
R
S
F
S
T
G
T
S
A
G
G
Site 72
S647
R
S
F
S
T
G
T
S
A
G
G
S
S
S
S
Site 73
S651
T
G
T
S
A
G
G
S
S
S
S
Q
Q
N
S
Site 74
S652
G
T
S
A
G
G
S
S
S
S
Q
Q
N
S
P
Site 75
S653
T
S
A
G
G
S
S
S
S
Q
Q
N
S
P
Q
Site 76
S654
S
A
G
G
S
S
S
S
Q
Q
N
S
P
Q
M
Site 77
S658
S
S
S
S
Q
Q
N
S
P
Q
M
K
N
S
P
Site 78
S664
N
S
P
Q
M
K
N
S
P
S
F
P
F
H
G
Site 79
S666
P
Q
M
K
N
S
P
S
F
P
F
H
G
S
R
Site 80
S672
P
S
F
P
F
H
G
S
R
P
A
G
L
P
G
Site 81
S682
A
G
L
P
G
L
G
S
S
T
Q
K
V
T
H
Site 82
S683
G
L
P
G
L
G
S
S
T
Q
K
V
T
H
R
Site 83
T688
G
S
S
T
Q
K
V
T
H
R
V
L
G
P
V
Site 84
S700
G
P
V
R
E
P
R
S
Q
D
R
R
R
Q
Q
Site 85
S717
L
N
H
R
P
A
G
S
L
A
P
S
P
A
P
Site 86
S721
P
A
G
S
L
A
P
S
P
A
P
T
S
S
G
Site 87
T725
L
A
P
S
P
A
P
T
S
S
G
P
A
S
S
Site 88
S726
A
P
S
P
A
P
T
S
S
G
P
A
S
S
H
Site 89
S727
P
S
P
A
P
T
S
S
G
P
A
S
S
H
K
Site 90
S731
P
T
S
S
G
P
A
S
S
H
K
L
G
S
C
Site 91
S732
T
S
S
G
P
A
S
S
H
K
L
G
S
C
L
Site 92
S737
A
S
S
H
K
L
G
S
C
L
L
P
D
S
F
Site 93
S743
G
S
C
L
L
P
D
S
F
N
I
P
G
S
S
Site 94
S749
D
S
F
N
I
P
G
S
S
C
S
L
L
S
S
Site 95
S752
N
I
P
G
S
S
C
S
L
L
S
S
G
D
K
Site 96
S755
G
S
S
C
S
L
L
S
S
G
D
K
P
E
A
Site 97
S756
S
S
C
S
L
L
S
S
G
D
K
P
E
A
V
Site 98
S794
R
P
R
L
G
R
G
S
P
P
T
R
R
G
M
Site 99
T797
L
G
R
G
S
P
P
T
R
R
G
M
K
G
S
Site 100
S804
T
R
R
G
M
K
G
S
S
G
P
T
S
P
T
Site 101
S805
R
R
G
M
K
G
S
S
G
P
T
S
P
T
P
Site 102
S809
K
G
S
S
G
P
T
S
P
T
P
R
T
R
E
Site 103
T811
S
S
G
P
T
S
P
T
P
R
T
R
E
S
S
Site 104
T814
P
T
S
P
T
P
R
T
R
E
S
S
E
L
E
Site 105
S817
P
T
P
R
T
R
E
S
S
E
L
E
L
G
S
Site 106
S818
T
P
R
T
R
E
S
S
E
L
E
L
G
S
C
Site 107
S824
S
S
E
L
E
L
G
S
C
S
A
T
P
G
L
Site 108
S826
E
L
E
L
G
S
C
S
A
T
P
G
L
P
Q
Site 109
T828
E
L
G
S
C
S
A
T
P
G
L
P
Q
A
R
Site 110
S841
A
R
P
P
R
P
R
S
A
P
A
F
S
P
I
Site 111
S846
P
R
S
A
P
A
F
S
P
I
S
C
S
L
S
Site 112
S851
A
F
S
P
I
S
C
S
L
S
D
S
P
S
W
Site 113
S853
S
P
I
S
C
S
L
S
D
S
P
S
W
N
C
Site 114
S855
I
S
C
S
L
S
D
S
P
S
W
N
C
Y
S
Site 115
S857
C
S
L
S
D
S
P
S
W
N
C
Y
S
R
G
Site 116
Y861
D
S
P
S
W
N
C
Y
S
R
G
P
L
G
Q
Site 117
S862
S
P
S
W
N
C
Y
S
R
G
P
L
G
Q
P
Site 118
T881
V
P
K
S
P
P
L
T
V
S
P
R
V
_
_
Site 119
S883
K
S
P
P
L
T
V
S
P
R
V
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation