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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C5orf25
Full Name:
Uncharacterized protein C5orf25
Alias:
Type:
Uncharacterized protein
Mass (Da):
96954
Number AA:
872
UniProt ID:
Q8NDZ2
International Prot ID:
IPI00374290
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
P
A
S
A
S
G
E
D
L
R
Site 2
T30
E
Q
D
F
I
D
L
T
R
E
T
R
P
R
T
Site 3
T33
F
I
D
L
T
R
E
T
R
P
R
T
K
D
R
Site 4
T37
T
R
E
T
R
P
R
T
K
D
R
S
G
L
Y
Site 5
S41
R
P
R
T
K
D
R
S
G
L
Y
V
I
D
L
Site 6
Y44
T
K
D
R
S
G
L
Y
V
I
D
L
T
R
A
Site 7
T49
G
L
Y
V
I
D
L
T
R
A
E
G
E
N
R
Site 8
T69
D
L
T
L
E
P
V
T
P
S
Q
K
E
P
T
Site 9
S71
T
L
E
P
V
T
P
S
Q
K
E
P
T
S
L
Site 10
S77
P
S
Q
K
E
P
T
S
L
Q
T
C
A
S
L
Site 11
S97
M
E
G
H
V
D
R
S
S
Q
P
T
A
R
R
Site 12
S98
E
G
H
V
D
R
S
S
Q
P
T
A
R
R
I
Site 13
T101
V
D
R
S
S
Q
P
T
A
R
R
I
I
N
S
Site 14
S108
T
A
R
R
I
I
N
S
D
P
V
D
L
D
L
Site 15
S131
P
P
P
A
T
S
I
S
G
G
S
V
Y
P
T
Site 16
S134
A
T
S
I
S
G
G
S
V
Y
P
T
E
P
N
Site 17
Y136
S
I
S
G
G
S
V
Y
P
T
E
P
N
C
S
Site 18
T138
S
G
G
S
V
Y
P
T
E
P
N
C
S
S
A
Site 19
S143
Y
P
T
E
P
N
C
S
S
A
T
F
T
G
N
Site 20
T146
E
P
N
C
S
S
A
T
F
T
G
N
L
S
F
Site 21
S164
L
Q
L
S
S
D
V
S
S
L
S
P
T
S
N
Site 22
S165
Q
L
S
S
D
V
S
S
L
S
P
T
S
N
N
Site 23
S167
S
S
D
V
S
S
L
S
P
T
S
N
N
S
R
Site 24
T169
D
V
S
S
L
S
P
T
S
N
N
S
R
S
S
Site 25
S170
V
S
S
L
S
P
T
S
N
N
S
R
S
S
S
Site 26
S173
L
S
P
T
S
N
N
S
R
S
S
S
S
S
S
Site 27
S175
P
T
S
N
N
S
R
S
S
S
S
S
S
N
Q
Site 28
S176
T
S
N
N
S
R
S
S
S
S
S
S
N
Q
K
Site 29
S177
S
N
N
S
R
S
S
S
S
S
S
N
Q
K
A
Site 30
S179
N
S
R
S
S
S
S
S
S
N
Q
K
A
P
L
Site 31
S180
S
R
S
S
S
S
S
S
N
Q
K
A
P
L
P
Site 32
S194
P
C
P
Q
Q
D
V
S
R
P
P
Q
A
L
P
Site 33
S214
L
P
C
P
P
R
A
S
P
C
P
P
R
A
S
Site 34
S221
S
P
C
P
P
R
A
S
S
C
P
P
R
A
L
Site 35
S222
P
C
P
P
R
A
S
S
C
P
P
R
A
L
S
Site 36
S229
S
C
P
P
R
A
L
S
C
P
S
Q
T
M
Q
Site 37
S232
P
R
A
L
S
C
P
S
Q
T
M
Q
C
Q
L
Site 38
T243
Q
C
Q
L
P
A
L
T
H
P
P
Q
E
V
P
Site 39
S263
I
P
G
P
P
Q
D
S
L
G
L
P
Q
D
V
Site 40
S276
D
V
P
G
L
P
Q
S
I
L
H
P
Q
D
V
Site 41
Y285
L
H
P
Q
D
V
A
Y
L
Q
D
M
P
R
S
Site 42
S292
Y
L
Q
D
M
P
R
S
P
G
D
V
P
Q
S
Site 43
S299
S
P
G
D
V
P
Q
S
P
S
D
V
S
P
S
Site 44
S301
G
D
V
P
Q
S
P
S
D
V
S
P
S
P
D
Site 45
S304
P
Q
S
P
S
D
V
S
P
S
P
D
A
P
Q
Site 46
S306
S
P
S
D
V
S
P
S
P
D
A
P
Q
S
P
Site 47
S312
P
S
P
D
A
P
Q
S
P
G
G
M
P
H
L
Site 48
S326
L
P
G
D
V
L
H
S
P
G
D
M
P
H
S
Site 49
S333
S
P
G
D
M
P
H
S
S
G
D
V
T
H
S
Site 50
S334
P
G
D
M
P
H
S
S
G
D
V
T
H
S
P
Site 51
T338
P
H
S
S
G
D
V
T
H
S
P
R
D
I
P
Site 52
S340
S
S
G
D
V
T
H
S
P
R
D
I
P
H
L
Site 53
T355
P
G
D
R
P
D
F
T
Q
N
D
V
Q
N
R
Site 54
S369
R
D
M
P
M
D
I
S
A
L
S
S
P
S
C
Site 55
S372
P
M
D
I
S
A
L
S
S
P
S
C
S
P
R
Site 56
S373
M
D
I
S
A
L
S
S
P
S
C
S
P
R
P
Site 57
S375
I
S
A
L
S
S
P
S
C
S
P
R
P
Q
S
Site 58
S377
A
L
S
S
P
S
C
S
P
R
P
Q
S
E
T
Site 59
S382
S
C
S
P
R
P
Q
S
E
T
P
L
E
K
V
Site 60
T384
S
P
R
P
Q
S
E
T
P
L
E
K
V
P
W
Site 61
S393
L
E
K
V
P
W
L
S
V
M
E
T
P
A
R
Site 62
T397
P
W
L
S
V
M
E
T
P
A
R
K
E
I
S
Site 63
S406
A
R
K
E
I
S
L
S
E
P
A
K
P
G
S
Site 64
S413
S
E
P
A
K
P
G
S
A
H
V
Q
S
R
T
Site 65
S418
P
G
S
A
H
V
Q
S
R
T
P
Q
G
G
L
Site 66
T420
S
A
H
V
Q
S
R
T
P
Q
G
G
L
Y
N
Site 67
Y426
R
T
P
Q
G
G
L
Y
N
R
P
C
L
H
R
Site 68
Y436
P
C
L
H
R
L
K
Y
F
L
R
P
P
V
H
Site 69
T456
T
L
I
P
D
K
D
T
R
E
N
K
G
Q
R
Site 70
T476
H
R
R
L
R
M
V
T
N
T
I
E
E
N
F
Site 71
T478
R
L
R
M
V
T
N
T
I
E
E
N
F
P
L
Site 72
S496
Q
F
L
M
D
F
V
S
P
Q
H
Y
P
P
R
Site 73
Y500
D
F
V
S
P
Q
H
Y
P
P
R
E
I
V
A
Site 74
T544
L
H
P
A
N
A
K
T
V
E
W
D
W
K
L
Site 75
T553
E
W
D
W
K
L
L
T
Y
V
M
E
E
E
G
Site 76
Y554
W
D
W
K
L
L
T
Y
V
M
E
E
E
G
Q
Site 77
T562
V
M
E
E
E
G
Q
T
L
P
G
R
V
L
F
Site 78
T576
F
L
R
Y
V
V
Q
T
L
E
D
D
F
Q
Q
Site 79
T584
L
E
D
D
F
Q
Q
T
L
R
R
Q
R
Q
H
Site 80
T627
A
V
T
E
D
G
L
T
Q
P
P
N
G
N
Q
Site 81
S637
P
N
G
N
Q
T
S
S
G
T
G
I
L
K
A
Site 82
S645
G
T
G
I
L
K
A
S
S
S
H
P
S
S
Q
Site 83
S646
T
G
I
L
K
A
S
S
S
H
P
S
S
Q
P
Site 84
S647
G
I
L
K
A
S
S
S
H
P
S
S
Q
P
N
Site 85
S650
K
A
S
S
S
H
P
S
S
Q
P
N
L
T
K
Site 86
S651
A
S
S
S
H
P
S
S
Q
P
N
L
T
K
N
Site 87
T680
I
A
V
E
V
D
R
T
P
T
C
S
S
N
K
Site 88
T682
V
E
V
D
R
T
P
T
C
S
S
N
K
I
A
Site 89
S684
V
D
R
T
P
T
C
S
S
N
K
I
A
E
M
Site 90
S703
V
L
D
I
P
E
R
S
Q
R
E
M
F
F
T
Site 91
T710
S
Q
R
E
M
F
F
T
T
M
E
S
H
L
L
Site 92
S752
Y
F
L
N
N
S
T
S
L
L
K
C
Q
S
D
Site 93
S758
T
S
L
L
K
C
Q
S
D
K
S
Q
W
Q
T
Site 94
T765
S
D
K
S
Q
W
Q
T
W
D
E
L
V
E
R
Site 95
S778
E
R
L
Q
F
L
L
S
S
Y
Q
H
V
L
R
Site 96
Y780
L
Q
F
L
L
S
S
Y
Q
H
V
L
R
E
H
Site 97
S790
V
L
R
E
H
L
R
S
S
V
I
D
R
K
D
Site 98
S791
L
R
E
H
L
R
S
S
V
I
D
R
K
D
L
Site 99
T814
P
Q
Q
G
D
D
I
T
V
V
D
V
E
K
Q
Site 100
S827
K
Q
I
E
A
F
R
S
R
L
I
Q
M
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation