KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CHDH
Full Name:
Choline dehydrogenase, mitochondrial
Alias:
Type:
Mass (Da):
65383
Number AA:
594
UniProt ID:
Q8NE62
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0008812
PhosphoSite+
KinaseNET
Biological Process:
GO:0006066
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
L
G
A
R
A
L
A
S
A
G
S
E
S
R
D
Site 2
S35
R
A
L
A
S
A
G
S
E
S
R
D
E
Y
S
Site 3
S37
L
A
S
A
G
S
E
S
R
D
E
Y
S
Y
V
Site 4
Y41
G
S
E
S
R
D
E
Y
S
Y
V
V
V
G
A
Site 5
S42
S
E
S
R
D
E
Y
S
Y
V
V
V
G
A
G
Site 6
Y43
E
S
R
D
E
Y
S
Y
V
V
V
G
A
G
S
Site 7
T60
C
V
L
A
G
R
L
T
E
D
P
A
E
R
V
Site 8
S81
P
K
D
V
L
A
G
S
K
R
L
S
W
K
I
Site 9
S85
L
A
G
S
K
R
L
S
W
K
I
H
M
P
A
Site 10
Y121
G
L
D
G
R
V
L
Y
W
P
R
G
R
V
W
Site 11
S131
R
G
R
V
W
G
G
S
S
S
L
N
A
M
V
Site 12
Y139
S
S
L
N
A
M
V
Y
V
R
G
H
A
E
D
Site 13
Y147
V
R
G
H
A
E
D
Y
E
R
W
Q
R
Q
G
Site 14
Y166
D
Y
A
H
C
L
P
Y
F
R
K
A
Q
G
H
Site 15
S178
Q
G
H
E
L
G
A
S
R
Y
R
G
A
D
G
Site 16
S190
A
D
G
P
L
R
V
S
R
G
K
T
N
H
P
Site 17
T194
L
R
V
S
R
G
K
T
N
H
P
L
H
C
A
Site 18
Y211
E
A
T
Q
Q
A
G
Y
P
L
T
E
D
M
N
Site 19
T214
Q
Q
A
G
Y
P
L
T
E
D
M
N
G
F
Q
Site 20
Y244
R
W
S
A
A
C
A
Y
L
H
P
A
L
S
R
Site 21
S250
A
Y
L
H
P
A
L
S
R
T
N
L
K
A
E
Site 22
Y277
T
R
A
V
G
V
E
Y
V
K
N
G
Q
S
H
Site 23
S283
E
Y
V
K
N
G
Q
S
H
R
A
Y
A
S
K
Site 24
Y287
N
G
Q
S
H
R
A
Y
A
S
K
E
V
I
L
Site 25
S289
Q
S
H
R
A
Y
A
S
K
E
V
I
L
S
G
Site 26
S308
S
P
Q
L
L
M
L
S
G
I
G
N
A
D
D
Site 27
Y341
L
Q
D
H
L
E
I
Y
I
Q
Q
A
C
T
R
Site 28
T351
Q
A
C
T
R
P
I
T
L
H
S
A
Q
K
P
Site 29
S354
T
R
P
I
T
L
H
S
A
Q
K
P
L
R
K
Site 30
S389
E
T
G
G
F
I
R
S
Q
P
G
V
P
H
P
Site 31
T415
I
D
H
G
R
V
P
T
Q
Q
E
A
Y
Q
V
Site 32
Y420
V
P
T
Q
Q
E
A
Y
Q
V
H
V
G
P
M
Site 33
T430
H
V
G
P
M
R
G
T
S
V
G
W
L
K
L
Site 34
S431
V
G
P
M
R
G
T
S
V
G
W
L
K
L
R
Site 35
Y452
H
P
V
I
Q
P
N
Y
L
S
T
E
T
D
I
Site 36
S454
V
I
Q
P
N
Y
L
S
T
E
T
D
I
E
D
Site 37
S490
G
K
E
L
Q
P
G
S
H
I
Q
S
D
K
E
Site 38
S494
Q
P
G
S
H
I
Q
S
D
K
E
I
D
A
F
Site 39
S508
F
V
R
A
K
A
D
S
A
Y
H
P
S
C
T
Site 40
Y510
R
A
K
A
D
S
A
Y
H
P
S
C
T
C
K
Site 41
T525
M
G
Q
P
S
D
P
T
A
V
V
D
P
Q
T
Site 42
T532
T
A
V
V
D
P
Q
T
R
V
L
G
V
E
N
Site 43
S546
N
L
R
V
V
D
A
S
I
M
P
S
M
V
S
Site 44
Y585
W
D
K
D
V
P
V
Y
K
P
R
T
L
A
T
Site 45
T589
V
P
V
Y
K
P
R
T
L
A
T
Q
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation