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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCF1
Full Name:
ATP-binding cassette sub-family F member 1
Alias:
ABC50; ATP-binding cassette 50; ATP-binding cassette, sub-family F (GCN20) member 1; EST123147; TNF-alpha-stimulated ABC protein
Type:
Transport protein, ABC
Mass (Da):
95926
Number AA:
845
UniProt ID:
Q8NE71
International Prot ID:
IPI00302146
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042626
GO:0008135
PhosphoSite+
KinaseNET
Biological Process:
GO:0006954
GO:0006412
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
E
W
I
G
D
G
E
S
T
S
P
S
D
K
V
Site 2
T21
W
I
G
D
G
E
S
T
S
P
S
D
K
V
V
Site 3
S22
I
G
D
G
E
S
T
S
P
S
D
K
V
V
K
Site 4
S24
D
G
E
S
T
S
P
S
D
K
V
V
K
K
G
Site 5
T40
K
D
K
K
I
K
K
T
F
F
E
E
L
A
V
Site 6
T79
Q
Q
K
K
K
R
D
T
R
K
G
R
R
K
K
Site 7
S105
M
E
R
L
K
K
L
S
V
P
T
S
D
E
E
Site 8
T108
L
K
K
L
S
V
P
T
S
D
E
E
D
E
V
Site 9
S109
K
K
L
S
V
P
T
S
D
E
E
D
E
V
P
Site 10
T126
K
P
R
G
G
K
K
T
K
G
G
N
V
F
A
Site 11
S140
A
A
L
I
Q
D
Q
S
E
E
E
E
E
E
E
Site 12
S166
N
R
I
N
K
A
V
S
E
E
Q
Q
P
A
L
Site 13
S183
K
K
G
K
E
E
K
S
K
G
K
A
K
P
Q
Site 14
S228
A
K
K
A
E
Q
G
S
E
E
E
G
E
G
E
Site 15
S244
E
E
E
E
G
G
E
S
K
A
D
D
P
Y
A
Site 16
Y250
E
S
K
A
D
D
P
Y
A
H
L
S
K
K
E
Site 17
S254
D
D
P
Y
A
H
L
S
K
K
E
K
K
K
L
Site 18
Y267
K
L
K
K
Q
M
E
Y
E
R
Q
V
A
S
L
Site 19
S273
E
Y
E
R
Q
V
A
S
L
K
A
A
N
A
A
Site 20
S285
N
A
A
E
N
D
F
S
V
S
Q
A
E
M
S
Site 21
S287
A
E
N
D
F
S
V
S
Q
A
E
M
S
S
R
Site 22
S292
S
V
S
Q
A
E
M
S
S
R
Q
A
M
L
E
Site 23
Y332
Y
I
V
A
G
R
R
Y
G
L
V
G
P
N
G
Site 24
T385
Q
A
V
L
R
A
D
T
K
R
L
K
L
L
E
Site 25
T407
Q
L
E
Q
G
D
D
T
A
A
E
R
L
E
K
Site 26
Y416
A
E
R
L
E
K
V
Y
E
E
L
R
A
T
G
Site 27
T422
V
Y
E
E
L
R
A
T
G
A
A
A
A
E
A
Site 28
T449
P
E
M
Q
N
R
P
T
Q
K
F
S
G
G
W
Site 29
Y493
A
V
I
W
L
N
N
Y
L
Q
G
W
R
K
T
Site 30
T500
Y
L
Q
G
W
R
K
T
L
L
I
V
S
H
D
Site 31
Y528
L
D
A
Q
R
L
H
Y
Y
R
G
N
Y
M
T
Site 32
Y533
L
H
Y
Y
R
G
N
Y
M
T
F
K
K
M
Y
Site 33
S595
R
K
N
Q
D
E
E
S
Q
E
A
P
E
L
L
Site 34
Y608
L
L
K
R
P
K
E
Y
T
V
R
F
T
F
P
Site 35
T609
L
K
R
P
K
E
Y
T
V
R
F
T
F
P
D
Site 36
T613
K
E
Y
T
V
R
F
T
F
P
D
P
P
P
L
Site 37
S621
F
P
D
P
P
P
L
S
P
P
V
L
G
L
H
Site 38
Y634
L
H
G
V
T
F
G
Y
Q
G
Q
K
P
L
F
Site 39
S665
G
P
N
G
V
G
K
S
T
L
L
L
L
L
T
Site 40
T666
P
N
G
V
G
K
S
T
L
L
L
L
L
T
G
Site 41
T676
L
L
L
T
G
K
L
T
P
T
H
G
E
M
R
Site 42
T678
L
T
G
K
L
T
P
T
H
G
E
M
R
K
N
Site 43
Y697
I
G
F
F
N
Q
Q
Y
A
E
Q
L
R
M
E
Site 44
T706
E
Q
L
R
M
E
E
T
P
T
E
Y
L
Q
R
Site 45
T708
L
R
M
E
E
T
P
T
E
Y
L
Q
R
G
F
Site 46
Y710
M
E
E
T
P
T
E
Y
L
Q
R
G
F
N
L
Site 47
Y719
Q
R
G
F
N
L
P
Y
Q
D
A
R
K
C
L
Site 48
S733
L
G
R
F
G
L
E
S
H
A
H
T
I
Q
I
Site 49
S777
T
N
N
L
D
I
E
S
I
D
A
L
G
E
A
Site 50
T803
S
H
D
A
R
L
I
T
E
T
N
C
Q
L
W
Site 51
S818
V
V
E
E
Q
S
V
S
Q
I
D
G
D
F
E
Site 52
Y827
I
D
G
D
F
E
D
Y
K
R
E
V
L
E
A
Site 53
S841
A
L
G
E
V
M
V
S
R
P
R
E
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation