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Updated November 2019
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Protein Info
Short Name:
CATSPER1
Full Name:
Cation channel sperm-associated protein 1
Alias:
Type:
Mass (Da):
90091
Number AA:
780
UniProt ID:
Q8NEC5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
N
A
D
R
F
F
R
S
H
S
S
P
P
H
H
Site 2
S27
D
R
F
F
R
S
H
S
S
P
P
H
H
R
P
Site 3
S28
R
F
F
R
S
H
S
S
P
P
H
H
R
P
G
Site 4
Y43
H
S
R
A
L
H
H
Y
E
L
H
H
H
G
V
Site 5
S57
V
P
H
Q
R
G
E
S
H
H
P
P
E
F
Q
Site 6
S72
D
F
H
D
Q
A
L
S
S
H
V
H
Q
S
H
Site 7
S78
L
S
S
H
V
H
Q
S
H
H
H
S
E
A
R
Site 8
S82
V
H
Q
S
H
H
H
S
E
A
R
N
H
G
R
Site 9
T94
H
G
R
A
H
G
P
T
G
F
G
L
A
P
S
Site 10
S101
T
G
F
G
L
A
P
S
Q
G
A
V
P
S
H
Site 11
S107
P
S
Q
G
A
V
P
S
H
R
S
Y
G
E
D
Site 12
Y111
A
V
P
S
H
R
S
Y
G
E
D
Y
H
D
E
Site 13
Y115
H
R
S
Y
G
E
D
Y
H
D
E
L
Q
R
D
Site 14
S130
G
R
R
H
H
D
G
S
Q
Y
G
G
F
H
Q
Site 15
Y143
H
Q
Q
S
D
S
H
Y
H
R
G
S
H
H
G
Site 16
Y154
S
H
H
G
R
P
Q
Y
L
G
E
N
L
S
H
Site 17
S160
Q
Y
L
G
E
N
L
S
H
Y
S
S
G
V
P
Site 18
Y162
L
G
E
N
L
S
H
Y
S
S
G
V
P
H
H
Site 19
S163
G
E
N
L
S
H
Y
S
S
G
V
P
H
H
G
Site 20
S164
E
N
L
S
H
Y
S
S
G
V
P
H
H
G
E
Site 21
S173
V
P
H
H
G
E
A
S
H
H
G
G
S
Y
L
Site 22
S178
E
A
S
H
H
G
G
S
Y
L
P
H
G
P
N
Site 23
Y179
A
S
H
H
G
G
S
Y
L
P
H
G
P
N
P
Site 24
Y187
L
P
H
G
P
N
P
Y
S
E
S
F
H
H
S
Site 25
S188
P
H
G
P
N
P
Y
S
E
S
F
H
H
S
E
Site 26
S190
G
P
N
P
Y
S
E
S
F
H
H
S
E
A
S
Site 27
S194
Y
S
E
S
F
H
H
S
E
A
S
H
L
S
G
Site 28
S197
S
F
H
H
S
E
A
S
H
L
S
G
L
Q
H
Site 29
S207
S
G
L
Q
H
D
E
S
Q
H
H
Q
V
P
H
Site 30
S240
E
A
H
Q
H
G
K
S
P
H
H
G
E
T
I
Site 31
T246
K
S
P
H
H
G
E
T
I
S
P
H
S
S
V
Site 32
S248
P
H
H
G
E
T
I
S
P
H
S
S
V
G
S
Site 33
S251
G
E
T
I
S
P
H
S
S
V
G
S
Y
Q
R
Site 34
S252
E
T
I
S
P
H
S
S
V
G
S
Y
Q
R
G
Site 35
S255
S
P
H
S
S
V
G
S
Y
Q
R
G
I
S
D
Site 36
Y256
P
H
S
S
V
G
S
Y
Q
R
G
I
S
D
Y
Site 37
S261
G
S
Y
Q
R
G
I
S
D
Y
H
S
E
Y
H
Site 38
Y263
Y
Q
R
G
I
S
D
Y
H
S
E
Y
H
Q
G
Site 39
Y267
I
S
D
Y
H
S
E
Y
H
Q
G
D
H
H
P
Site 40
Y309
H
Q
D
H
H
G
A
Y
H
S
S
Y
L
H
G
Site 41
Y313
H
G
A
Y
H
S
S
Y
L
H
G
D
Y
V
Q
Site 42
Y318
S
S
Y
L
H
G
D
Y
V
Q
S
T
S
Q
L
Site 43
S321
L
H
G
D
Y
V
Q
S
T
S
Q
L
S
I
P
Site 44
T322
H
G
D
Y
V
Q
S
T
S
Q
L
S
I
P
H
Site 45
S323
G
D
Y
V
Q
S
T
S
Q
L
S
I
P
H
T
Site 46
S326
V
Q
S
T
S
Q
L
S
I
P
H
T
S
R
S
Site 47
T330
S
Q
L
S
I
P
H
T
S
R
S
L
I
H
D
Site 48
S333
S
I
P
H
T
S
R
S
L
I
H
D
A
P
G
Site 49
S344
D
A
P
G
P
A
A
S
R
T
G
V
F
P
Y
Site 50
T346
P
G
P
A
A
S
R
T
G
V
F
P
Y
H
V
Site 51
Y351
S
R
T
G
V
F
P
Y
H
V
A
H
P
R
G
Site 52
S359
H
V
A
H
P
R
G
S
A
H
S
M
T
R
S
Site 53
S362
H
P
R
G
S
A
H
S
M
T
R
S
S
S
T
Site 54
T364
R
G
S
A
H
S
M
T
R
S
S
S
T
I
R
Site 55
S366
S
A
H
S
M
T
R
S
S
S
T
I
R
S
R
Site 56
S367
A
H
S
M
T
R
S
S
S
T
I
R
S
R
V
Site 57
S368
H
S
M
T
R
S
S
S
T
I
R
S
R
V
T
Site 58
T369
S
M
T
R
S
S
S
T
I
R
S
R
V
T
Q
Site 59
S372
R
S
S
S
T
I
R
S
R
V
T
Q
M
S
K
Site 60
T375
S
T
I
R
S
R
V
T
Q
M
S
K
K
V
H
Site 61
S378
R
S
R
V
T
Q
M
S
K
K
V
H
T
Q
D
Site 62
T383
Q
M
S
K
K
V
H
T
Q
D
I
S
T
K
H
Site 63
S391
Q
D
I
S
T
K
H
S
E
D
W
G
K
E
E
Site 64
T406
G
Q
F
Q
K
R
K
T
G
R
L
Q
R
T
R
Site 65
S418
R
T
R
K
K
G
H
S
T
N
L
F
Q
W
L
Site 66
T444
R
E
M
I
R
N
L
T
Q
S
L
A
F
E
T
Site 67
Y537
Q
T
H
S
F
A
I
Y
H
Q
S
L
F
R
I
Site 68
S568
R
R
L
S
F
L
T
S
V
Q
E
V
T
G
T
Site 69
T575
S
V
Q
E
V
T
G
T
L
G
Q
S
L
P
S
Site 70
S608
L
R
A
L
F
R
K
S
D
P
K
R
F
Q
N
Site 71
S633
L
L
T
L
D
D
W
S
L
I
Y
M
D
S
R
Site 72
Y636
L
D
D
W
S
L
I
Y
M
D
S
R
A
Q
G
Site 73
S701
Q
E
K
L
L
E
D
S
L
T
E
L
R
A
A
Site 74
T703
K
L
L
E
D
S
L
T
E
L
R
A
A
E
P
Site 75
S748
H
Y
L
Q
L
V
A
S
V
E
Q
E
Q
Q
K
Site 76
T769
V
I
D
E
I
V
D
T
T
F
E
A
G
E
E
Site 77
T770
I
D
E
I
V
D
T
T
F
E
A
G
E
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation