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Updated November 2019
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Protein Info
Short Name:
FAM116B
Full Name:
Protein FAM116B
Alias:
Type:
Mass (Da):
66464
Number AA:
585
UniProt ID:
Q8NEG7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
L
G
A
A
G
P
T
S
S
G
R
A
A
R
T
Site 2
S24
G
A
A
G
P
T
S
S
G
R
A
A
R
T
P
Site 3
T30
S
S
G
R
A
A
R
T
P
A
A
P
W
A
R
Site 4
Y62
G
Q
A
L
E
L
V
Y
P
N
D
F
R
L
T
Site 5
T69
Y
P
N
D
F
R
L
T
D
K
E
K
S
S
I
Site 6
S74
R
L
T
D
K
E
K
S
S
I
C
Y
L
S
F
Site 7
S75
L
T
D
K
E
K
S
S
I
C
Y
L
S
F
P
Site 8
Y78
K
E
K
S
S
I
C
Y
L
S
F
P
D
S
H
Site 9
S80
K
S
S
I
C
Y
L
S
F
P
D
S
H
S
G
Site 10
S84
C
Y
L
S
F
P
D
S
H
S
G
C
L
G
D
Site 11
S86
L
S
F
P
D
S
H
S
G
C
L
G
D
T
Q
Site 12
S106
R
Q
C
G
G
Q
R
S
P
W
H
A
D
D
R
Site 13
Y115
W
H
A
D
D
R
H
Y
N
S
R
A
P
V
A
Site 14
Y130
L
Q
R
E
P
A
H
Y
F
G
Y
V
Y
F
R
Site 15
Y133
E
P
A
H
Y
F
G
Y
V
Y
F
R
Q
V
K
Site 16
Y135
A
H
Y
F
G
Y
V
Y
F
R
Q
V
K
D
S
Site 17
S142
Y
F
R
Q
V
K
D
S
S
V
K
R
G
Y
F
Site 18
S143
F
R
Q
V
K
D
S
S
V
K
R
G
Y
F
Q
Site 19
Y148
D
S
S
V
K
R
G
Y
F
Q
K
S
L
V
L
Site 20
S152
K
R
G
Y
F
Q
K
S
L
V
L
V
S
R
L
Site 21
S218
V
V
Q
V
R
I
P
S
R
V
D
K
S
E
S
Site 22
S223
I
P
S
R
V
D
K
S
E
S
S
P
P
K
Q
Site 23
S225
S
R
V
D
K
S
E
S
S
P
P
K
Q
F
D
Site 24
S226
R
V
D
K
S
E
S
S
P
P
K
Q
F
D
Q
Site 25
T323
F
K
E
F
T
T
R
T
Q
A
P
P
N
V
V
Site 26
T374
K
K
P
S
R
L
K
T
L
D
T
K
P
G
L
Site 27
T377
S
R
L
K
T
L
D
T
K
P
G
L
Y
T
A
Site 28
Y382
L
D
T
K
P
G
L
Y
T
A
Y
T
A
H
L
Site 29
Y385
K
P
G
L
Y
T
A
Y
T
A
H
L
H
R
D
Site 30
T386
P
G
L
Y
T
A
Y
T
A
H
L
H
R
D
K
Site 31
S409
G
V
Q
K
K
R
P
S
D
V
Q
S
A
L
L
Site 32
S413
K
R
P
S
D
V
Q
S
A
L
L
R
R
H
L
Site 33
S444
S
L
M
P
L
Q
K
S
I
T
P
W
K
T
P
Site 34
T446
M
P
L
Q
K
S
I
T
P
W
K
T
P
P
Q
Site 35
T450
K
S
I
T
P
W
K
T
P
P
Q
I
Q
P
F
Site 36
S458
P
P
Q
I
Q
P
F
S
Q
D
D
F
L
R
S
Site 37
S465
S
Q
D
D
F
L
R
S
L
E
H
A
G
P
Q
Site 38
Y485
K
G
D
W
L
G
L
Y
R
R
F
F
K
S
P
Site 39
Y498
S
P
H
F
D
G
W
Y
R
Q
R
H
K
E
M
Site 40
S530
E
T
W
M
K
D
K
S
E
V
E
V
V
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation