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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF548
Full Name:
Zinc finger protein 548
Alias:
Type:
Mass (Da):
62728
Number AA:
533
UniProt ID:
Q8NEK5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
V
F
E
D
V
A
I
Y
F
S
Q
E
E
W
G
Site 2
Y33
D
E
A
Q
R
L
L
Y
R
D
V
M
L
E
N
Site 3
S49
A
L
L
S
S
L
G
S
W
H
G
A
E
D
E
Site 4
S58
H
G
A
E
D
E
E
S
P
S
Q
Q
G
F
S
Site 5
S60
A
E
D
E
E
S
P
S
Q
Q
G
F
S
V
G
Site 6
S65
S
P
S
Q
Q
G
F
S
V
G
V
S
E
V
T
Site 7
S69
Q
G
F
S
V
G
V
S
E
V
T
T
S
K
P
Site 8
S74
G
V
S
E
V
T
T
S
K
P
C
L
S
S
Q
Site 9
S79
T
T
S
K
P
C
L
S
S
Q
K
V
H
P
S
Site 10
S80
T
S
K
P
C
L
S
S
Q
K
V
H
P
S
E
Site 11
S86
S
S
Q
K
V
H
P
S
E
T
C
G
P
P
L
Site 12
T88
Q
K
V
H
P
S
E
T
C
G
P
P
L
K
D
Site 13
S131
Q
Q
I
G
E
N
L
S
R
G
D
D
W
I
P
Site 14
T165
G
W
K
D
L
P
A
T
S
C
L
L
Q
H
Q
Site 15
Y181
P
Q
S
E
W
K
P
Y
R
D
T
E
D
R
E
Site 16
T184
E
W
K
P
Y
R
D
T
E
D
R
E
A
F
Q
Site 17
T192
E
D
R
E
A
F
Q
T
G
Q
N
D
Y
K
C
Site 18
Y197
F
Q
T
G
Q
N
D
Y
K
C
S
E
C
G
K
Site 19
T205
K
C
S
E
C
G
K
T
F
T
C
S
Y
S
F
Site 20
T207
S
E
C
G
K
T
F
T
C
S
Y
S
F
V
E
Site 21
Y210
G
K
T
F
T
C
S
Y
S
F
V
E
H
Q
K
Site 22
T220
V
E
H
Q
K
I
H
T
G
E
R
S
Y
E
C
Site 23
Y225
I
H
T
G
E
R
S
Y
E
C
N
K
C
G
K
Site 24
T245
A
N
F
M
K
H
Q
T
V
H
T
S
E
R
T
Site 25
Y253
V
H
T
S
E
R
T
Y
E
C
R
E
C
G
K
Site 26
Y266
G
K
S
F
M
Y
N
Y
R
L
M
R
H
K
R
Site 27
T276
M
R
H
K
R
V
H
T
G
E
R
P
Y
E
C
Site 28
Y281
V
H
T
G
E
R
P
Y
E
C
N
T
C
G
K
Site 29
Y292
T
C
G
K
F
F
R
Y
S
S
T
F
V
R
H
Site 30
S294
G
K
F
F
R
Y
S
S
T
F
V
R
H
Q
R
Site 31
T295
K
F
F
R
Y
S
S
T
F
V
R
H
Q
R
V
Site 32
T304
V
R
H
Q
R
V
H
T
G
E
R
P
Y
E
C
Site 33
Y309
V
H
T
G
E
R
P
Y
E
C
R
E
C
G
K
Site 34
S322
G
K
F
F
M
D
S
S
T
L
I
K
H
Q
R
Site 35
T323
K
F
F
M
D
S
S
T
L
I
K
H
Q
R
V
Site 36
T332
I
K
H
Q
R
V
H
T
G
E
R
P
Y
K
C
Site 37
Y337
V
H
T
G
E
R
P
Y
K
C
N
D
C
G
K
Site 38
Y348
D
C
G
K
F
F
R
Y
I
S
T
L
I
R
H
Site 39
S350
G
K
F
F
R
Y
I
S
T
L
I
R
H
Q
R
Site 40
T360
I
R
H
Q
R
I
H
T
G
E
R
P
Y
E
C
Site 41
Y365
I
H
T
G
E
R
P
Y
E
C
S
V
C
G
E
Site 42
S368
G
E
R
P
Y
E
C
S
V
C
G
E
L
F
R
Site 43
Y376
V
C
G
E
L
F
R
Y
N
S
S
L
V
K
H
Site 44
S378
G
E
L
F
R
Y
N
S
S
L
V
K
H
W
R
Site 45
S379
E
L
F
R
Y
N
S
S
L
V
K
H
W
R
N
Site 46
T388
V
K
H
W
R
N
H
T
G
E
R
P
Y
K
C
Site 47
Y393
N
H
T
G
E
R
P
Y
K
C
S
E
C
G
K
Site 48
S396
G
E
R
P
Y
K
C
S
E
C
G
K
S
F
R
Site 49
Y404
E
C
G
K
S
F
R
Y
H
C
R
L
I
R
H
Site 50
T416
I
R
H
Q
R
V
H
T
G
E
R
P
Y
E
C
Site 51
Y421
V
H
T
G
E
R
P
Y
E
C
S
E
C
G
K
Site 52
Y432
E
C
G
K
F
F
R
Y
N
S
N
L
I
K
H
Site 53
T444
I
K
H
W
R
N
H
T
G
E
R
P
Y
E
C
Site 54
Y449
N
H
T
G
E
R
P
Y
E
C
R
E
C
G
K
Site 55
S459
R
E
C
G
K
A
F
S
H
K
H
I
L
V
E
Site 56
Y477
I
H
S
G
E
R
P
Y
E
C
S
E
C
Q
K
Site 57
S500
V
H
H
Q
K
I
H
S
E
E
R
L
V
C
S
Site 58
S513
C
S
M
N
V
G
N
S
L
A
K
T
P
T
S
Site 59
T517
V
G
N
S
L
A
K
T
P
T
S
L
N
I
R
Site 60
S520
S
L
A
K
T
P
T
S
L
N
I
R
D
F
T
Site 61
T527
S
L
N
I
R
D
F
T
M
E
K
V
Y
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation