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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF680
Full Name:
Zinc finger protein 680
Alias:
Type:
Mass (Da):
61798
Number AA:
530
UniProt ID:
Q8NEM1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
P
G
P
P
G
S
L
E
M
G
P
L
T
Site 2
S23
R
D
V
A
I
E
F
S
L
E
E
W
Q
C
L
Site 3
Y38
D
T
A
Q
R
N
L
Y
R
K
V
M
F
E
N
Site 4
S99
E
D
L
W
P
E
H
S
I
K
D
S
F
Q
K
Site 5
S103
P
E
H
S
I
K
D
S
F
Q
K
V
I
L
R
Site 6
Y112
Q
K
V
I
L
R
G
Y
G
K
C
G
H
E
N
Site 7
S125
E
N
L
Q
L
R
I
S
C
K
S
V
D
E
S
Site 8
S128
Q
L
R
I
S
C
K
S
V
D
E
S
K
V
F
Site 9
S132
S
C
K
S
V
D
E
S
K
V
F
K
E
G
Y
Site 10
Y139
S
K
V
F
K
E
G
Y
N
E
L
N
Q
C
L
Site 11
T148
E
L
N
Q
C
L
R
T
T
Q
S
K
I
F
Q
Site 12
T149
L
N
Q
C
L
R
T
T
Q
S
K
I
F
Q
C
Site 13
S151
Q
C
L
R
T
T
Q
S
K
I
F
Q
C
D
K
Site 14
Y159
K
I
F
Q
C
D
K
Y
V
K
V
F
H
K
F
Site 15
S167
V
K
V
F
H
K
F
S
N
S
N
S
H
K
K
Site 16
S169
V
F
H
K
F
S
N
S
N
S
H
K
K
R
N
Site 17
S171
H
K
F
S
N
S
N
S
H
K
K
R
N
T
G
Site 18
T177
N
S
H
K
K
R
N
T
G
K
K
V
F
K
C
Site 19
T205
T
Q
H
I
R
I
H
T
R
E
N
S
Y
K
C
Site 20
S223
G
K
V
L
N
W
F
S
E
L
I
K
H
K
G
Site 21
Y238
I
H
M
G
E
K
P
Y
K
C
E
E
C
G
K
Site 22
S250
C
G
K
A
F
N
Q
S
S
T
L
I
K
H
K
Site 23
S251
G
K
A
F
N
Q
S
S
T
L
I
K
H
K
K
Site 24
Y294
I
H
T
G
D
K
P
Y
K
C
D
E
C
H
K
Site 25
T317
T
N
H
K
R
I
H
T
G
E
K
P
F
K
C
Site 26
S335
G
K
D
F
N
Q
F
S
N
L
T
K
H
K
K
Site 27
T345
T
K
H
K
K
I
H
T
G
E
K
P
Y
K
C
Site 28
T373
T
R
H
K
K
I
H
T
G
E
K
S
Y
K
C
Site 29
S390
C
G
K
A
F
I
Q
S
S
N
L
T
E
H
M
Site 30
S391
G
K
A
F
I
Q
S
S
N
L
T
E
H
M
R
Site 31
T401
T
E
H
M
R
I
H
T
G
E
K
P
Y
K
C
Site 32
S420
K
A
F
N
G
C
S
S
L
T
R
H
K
R
I
Site 33
T429
T
R
H
K
R
I
H
T
R
E
N
T
Y
K
C
Site 34
T433
R
I
H
T
R
E
N
T
Y
K
C
E
E
C
G
Site 35
Y434
I
H
T
R
E
N
T
Y
K
C
E
E
C
G
K
Site 36
S447
G
K
G
F
T
L
F
S
T
L
T
N
H
K
V
Site 37
Y462
I
H
T
G
E
K
S
Y
K
C
D
E
C
G
N
Site 38
S502
C
G
K
A
F
N
R
S
S
H
L
T
R
H
K
Site 39
S503
G
K
A
F
N
R
S
S
H
L
T
R
H
K
K
Site 40
T506
F
N
R
S
S
H
L
T
R
H
K
K
I
H
T
Site 41
T513
T
R
H
K
K
I
H
T
G
E
K
L
Y
K
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation