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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARMC2
Full Name:
Armadillo repeat-containing protein 2
Alias:
Armadillo repeat containing 2
Type:
Mass (Da):
96867
Number AA:
867
UniProt ID:
Q8NEN0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
L
S
P
N
D
K
M
L
G
Site 2
Y16
L
G
K
L
D
P
F
Y
Q
P
S
V
S
K
Q
Site 3
S19
L
D
P
F
Y
Q
P
S
V
S
K
Q
K
T
S
Site 4
S21
P
F
Y
Q
P
S
V
S
K
Q
K
T
S
A
E
Site 5
T25
P
S
V
S
K
Q
K
T
S
A
E
I
I
S
E
Site 6
T39
E
A
R
N
A
L
R
T
V
R
T
Q
R
P
F
Site 7
T42
N
A
L
R
T
V
R
T
Q
R
P
F
T
P
Q
Site 8
T47
V
R
T
Q
R
P
F
T
P
Q
E
A
Q
R
K
Site 9
S60
R
K
L
F
G
P
A
S
S
R
T
S
E
N
R
Site 10
S64
G
P
A
S
S
R
T
S
E
N
R
P
P
S
S
Site 11
S70
T
S
E
N
R
P
P
S
S
F
S
L
H
A
S
Site 12
S71
S
E
N
R
P
P
S
S
F
S
L
H
A
S
S
Site 13
S73
N
R
P
P
S
S
F
S
L
H
A
S
S
F
E
Site 14
S77
S
S
F
S
L
H
A
S
S
F
E
S
S
D
S
Site 15
S78
S
F
S
L
H
A
S
S
F
E
S
S
D
S
R
Site 16
S81
L
H
A
S
S
F
E
S
S
D
S
R
P
I
S
Site 17
S82
H
A
S
S
F
E
S
S
D
S
R
P
I
S
G
Site 18
S84
S
S
F
E
S
S
D
S
R
P
I
S
G
T
R
Site 19
S88
S
S
D
S
R
P
I
S
G
T
R
L
S
P
L
Site 20
T90
D
S
R
P
I
S
G
T
R
L
S
P
L
E
L
Site 21
S93
P
I
S
G
T
R
L
S
P
L
E
L
K
P
K
Site 22
S104
L
K
P
K
V
P
A
S
P
T
R
E
E
D
S
Site 23
S111
S
P
T
R
E
E
D
S
C
F
S
F
P
K
P
Site 24
S114
R
E
E
D
S
C
F
S
F
P
K
P
P
V
D
Site 25
S129
P
A
K
I
R
R
V
S
N
A
R
A
R
L
F
Site 26
S140
A
R
L
F
R
A
A
S
Q
R
A
L
L
P
D
Site 27
S149
R
A
L
L
P
D
R
S
L
P
P
S
D
S
K
Site 28
S153
P
D
R
S
L
P
P
S
D
S
K
K
T
V
E
Site 29
S155
R
S
L
P
P
S
D
S
K
K
T
V
E
S
K
Site 30
T158
P
P
S
D
S
K
K
T
V
E
S
K
E
T
V
Site 31
T164
K
T
V
E
S
K
E
T
V
M
M
G
D
S
M
Site 32
T196
K
S
H
P
L
Q
L
T
D
D
G
G
F
S
E
Site 33
T214
Q
E
M
F
K
G
T
T
S
L
P
S
H
L
K
Site 34
S215
E
M
F
K
G
T
T
S
L
P
S
H
L
K
N
Site 35
S218
K
G
T
T
S
L
P
S
H
L
K
N
G
G
D
Site 36
S234
G
K
R
H
A
R
A
S
S
C
P
S
S
S
D
Site 37
S235
K
R
H
A
R
A
S
S
C
P
S
S
S
D
L
Site 38
S238
A
R
A
S
S
C
P
S
S
S
D
L
S
R
L
Site 39
S239
R
A
S
S
C
P
S
S
S
D
L
S
R
L
Q
Site 40
S240
A
S
S
C
P
S
S
S
D
L
S
R
L
Q
T
Site 41
S243
C
P
S
S
S
D
L
S
R
L
Q
T
K
A
V
Site 42
T247
S
D
L
S
R
L
Q
T
K
A
V
P
K
A
D
Site 43
T288
E
K
E
E
N
I
E
T
V
C
A
A
C
T
Q
Site 44
S360
C
K
L
I
F
K
I
S
R
N
E
K
N
D
S
Site 45
S367
S
R
N
E
K
N
D
S
L
I
Q
N
D
S
I
Site 46
S373
D
S
L
I
Q
N
D
S
I
L
E
S
L
L
E
Site 47
S377
Q
N
D
S
I
L
E
S
L
L
E
V
L
R
S
Site 48
S384
S
L
L
E
V
L
R
S
E
D
L
Q
T
N
M
Site 49
T389
L
R
S
E
D
L
Q
T
N
M
E
A
F
L
Y
Site 50
T439
E
N
I
K
K
C
G
T
F
L
P
N
S
G
H
Site 51
T452
G
H
L
L
V
Q
V
T
A
T
L
R
N
L
V
Site 52
S461
T
L
R
N
L
V
D
S
S
L
V
R
S
K
F
Site 53
T492
K
G
D
K
D
V
C
T
N
I
A
R
I
F
S
Site 54
S499
T
N
I
A
R
I
F
S
K
L
T
S
Y
R
D
Site 55
S503
R
I
F
S
K
L
T
S
Y
R
D
C
C
T
A
Site 56
T509
T
S
Y
R
D
C
C
T
A
L
A
S
Y
S
R
Site 57
S562
Q
F
S
K
E
K
G
S
I
Q
T
L
L
S
L
Site 58
S580
F
H
Q
L
D
L
H
S
Q
K
P
V
G
Q
R
Site 59
S598
H
R
A
Q
R
P
P
S
E
A
E
D
V
L
I
Site 60
S642
L
T
T
L
E
Y
K
S
L
D
D
C
E
E
L
Site 61
S661
T
A
T
I
N
N
L
S
Y
Y
Q
V
K
N
S
Site 62
Y662
A
T
I
N
N
L
S
Y
Y
Q
V
K
N
S
I
Site 63
Y663
T
I
N
N
L
S
Y
Y
Q
V
K
N
S
I
I
Site 64
S704
V
R
V
F
G
N
L
S
Q
D
H
D
V
C
D
Site 65
S796
S
E
N
I
T
N
A
S
S
C
F
G
N
E
D
Site 66
S824
E
E
L
A
L
D
G
S
F
D
P
D
L
K
N
Site 67
T857
N
R
I
Q
R
H
H
T
F
L
E
P
L
P
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation