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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHDC9
Full Name:
Kelch domain-containing protein 9
Alias:
KARCA1; kelch domain containing 9; kelch/ankyrin repeat containing cyclin A1 interacting; kelch/ankyrin repeat containing cyclin A1 interacting protein; KLDC9
Type:
Unknown function
Mass (Da):
37750
Number AA:
UniProt ID:
Q8NEP7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
L
L
A
R
A
F
H
S
C
T
E
L
R
G
R
Site 2
T34
A
R
A
F
H
S
C
T
E
L
R
G
R
F
Y
Site 3
S55
A
G
G
A
R
E
P
S
S
D
T
V
V
F
D
Site 4
S56
G
G
A
R
E
P
S
S
D
T
V
V
F
D
P
Site 5
T58
A
R
E
P
S
S
D
T
V
V
F
D
P
A
R
Site 6
S76
V
R
L
G
A
R
G
S
P
P
R
S
H
H
D
Site 7
S80
A
R
G
S
P
P
R
S
H
H
D
A
A
P
V
Site 8
S101
V
V
G
G
W
D
G
S
R
R
L
A
T
V
T
Site 9
T106
D
G
S
R
R
L
A
T
V
T
A
L
D
T
E
Site 10
T108
S
R
R
L
A
T
V
T
A
L
D
T
E
R
G
Site 11
T112
A
T
V
T
A
L
D
T
E
R
G
V
W
E
A
Site 12
T123
V
W
E
A
W
T
G
T
P
G
D
C
P
P
A
Site 13
S133
D
C
P
P
A
G
L
S
S
H
T
C
T
R
I
Site 14
S134
C
P
P
A
G
L
S
S
H
T
C
T
R
I
S
Site 15
T136
P
A
G
L
S
S
H
T
C
T
R
I
S
D
R
Site 16
T138
G
L
S
S
H
T
C
T
R
I
S
D
R
E
L
Site 17
S141
S
H
T
C
T
R
I
S
D
R
E
L
Q
V
A
Site 18
T156
G
R
E
G
G
I
H
T
Q
R
R
Y
G
S
I
Site 19
Y160
G
I
H
T
Q
R
R
Y
G
S
I
Y
T
L
R
Site 20
S162
H
T
Q
R
R
Y
G
S
I
Y
T
L
R
L
D
Site 21
Y164
Q
R
R
Y
G
S
I
Y
T
L
R
L
D
P
S
Site 22
T165
R
R
Y
G
S
I
Y
T
L
R
L
D
P
S
A
Site 23
S171
Y
T
L
R
L
D
P
S
A
R
T
Y
C
Y
K
Site 24
Y175
L
D
P
S
A
R
T
Y
C
Y
K
Q
E
G
C
Site 25
Y177
P
S
A
R
T
Y
C
Y
K
Q
E
G
C
H
T
Site 26
T184
Y
K
Q
E
G
C
H
T
A
S
R
S
G
H
C
Site 27
S186
Q
E
G
C
H
T
A
S
R
S
G
H
C
A
A
Site 28
T197
H
C
A
A
L
L
Q
T
P
G
P
H
P
G
H
Site 29
S247
E
Q
L
A
R
L
V
S
S
G
Q
G
S
Q
K
Site 30
S248
Q
L
A
R
L
V
S
S
G
Q
G
S
Q
K
G
Site 31
S252
L
V
S
S
G
Q
G
S
Q
K
G
P
H
G
L
Site 32
S263
P
H
G
L
R
H
H
S
C
S
V
V
G
P
F
Site 33
T280
L
F
G
G
E
T
L
T
R
A
R
D
T
I
C
Site 34
T285
T
L
T
R
A
R
D
T
I
C
N
D
L
Y
I
Site 35
Y291
D
T
I
C
N
D
L
Y
I
Y
D
T
R
T
S
Site 36
Y293
I
C
N
D
L
Y
I
Y
D
T
R
T
S
P
P
Site 37
T295
N
D
L
Y
I
Y
D
T
R
T
S
P
P
L
W
Site 38
T338
G
F
G
E
D
G
R
T
A
S
P
Q
V
C
I
Site 39
S340
G
E
D
G
R
T
A
S
P
Q
V
C
I
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation