KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
VR1
Full Name:
Transient receptor potential cation channel subfamily V member 1
Alias:
Capsaicin receptor; Transient receptor cation channel V1; Transient receptor potential cation channel, subfamily V, member 1; TRPV1; Vanilloid receptor 1
Type:
Channel, cation; Receptor, misc.
Mass (Da):
94938
Number AA:
839
UniProt ID:
Q8NER1
International Prot ID:
IPI00744280
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005262
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0007166
GO:0007635
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
K
K
W
S
S
T
D
L
G
A
A
A
Site 2
T20
A
D
P
L
Q
K
D
T
C
P
D
P
L
D
G
Site 3
S31
P
L
D
G
D
P
N
S
R
P
P
P
A
K
P
Site 4
S41
P
P
A
K
P
Q
L
S
T
A
K
S
R
T
R
Site 5
S45
P
Q
L
S
T
A
K
S
R
T
R
L
F
G
K
Site 6
S55
R
L
F
G
K
G
D
S
E
E
A
F
P
V
D
Site 7
S72
H
E
E
G
E
L
D
S
C
P
T
I
T
V
S
Site 8
T92
Q
R
P
G
D
G
P
T
G
A
R
L
L
S
Q
Site 9
S98
P
T
G
A
R
L
L
S
Q
D
S
V
A
A
S
Site 10
S101
A
R
L
L
S
Q
D
S
V
A
A
S
T
E
K
Site 11
S105
S
Q
D
S
V
A
A
S
T
E
K
T
L
R
L
Site 12
T109
V
A
A
S
T
E
K
T
L
R
L
Y
D
R
R
Site 13
Y113
T
E
K
T
L
R
L
Y
D
R
R
S
I
F
E
Site 14
S117
L
R
L
Y
D
R
R
S
I
F
E
A
V
A
Q
Site 15
S132
N
N
C
Q
D
L
E
S
L
L
L
F
L
Q
K
Site 16
S140
L
L
L
F
L
Q
K
S
K
K
H
L
T
D
N
Site 17
T145
Q
K
S
K
K
H
L
T
D
N
E
F
K
D
P
Site 18
T154
N
E
F
K
D
P
E
T
G
K
T
C
L
L
K
Site 19
T157
K
D
P
E
T
G
K
T
C
L
L
K
A
M
L
Site 20
S186
E
I
A
R
Q
T
D
S
L
K
E
L
V
N
A
Site 21
S194
L
K
E
L
V
N
A
S
Y
T
D
S
Y
Y
K
Site 22
Y195
K
E
L
V
N
A
S
Y
T
D
S
Y
Y
K
G
Site 23
S198
V
N
A
S
Y
T
D
S
Y
Y
K
G
Q
T
A
Site 24
Y199
N
A
S
Y
T
D
S
Y
Y
K
G
Q
T
A
L
Site 25
Y200
A
S
Y
T
D
S
Y
Y
K
G
Q
T
A
L
H
Site 26
T240
H
G
D
F
F
K
K
T
K
G
R
P
G
F
Y
Site 27
Y247
T
K
G
R
P
G
F
Y
F
G
E
L
P
L
S
Site 28
S272
V
K
F
L
L
Q
N
S
W
Q
T
A
D
I
S
Site 29
S279
S
W
Q
T
A
D
I
S
A
R
D
S
V
G
N
Site 30
S283
A
D
I
S
A
R
D
S
V
G
N
T
V
L
H
Site 31
T303
A
D
N
T
A
D
N
T
K
F
V
T
S
M
Y
Site 32
Y310
T
K
F
V
T
S
M
Y
N
E
I
L
I
L
G
Site 33
S367
E
P
E
C
R
H
L
S
R
K
F
T
E
W
A
Site 34
T371
R
H
L
S
R
K
F
T
E
W
A
Y
G
P
V
Site 35
Y375
R
K
F
T
E
W
A
Y
G
P
V
H
S
S
L
Site 36
Y383
G
P
V
H
S
S
L
Y
D
L
S
C
I
D
T
Site 37
S386
H
S
S
L
Y
D
L
S
C
I
D
T
C
E
K
Site 38
T390
Y
D
L
S
C
I
D
T
C
E
K
N
S
V
L
Site 39
Y402
S
V
L
E
V
I
A
Y
S
S
S
E
T
P
N
Site 40
S405
E
V
I
A
Y
S
S
S
E
T
P
N
R
H
D
Site 41
T407
I
A
Y
S
S
S
E
T
P
N
R
H
D
M
L
Site 42
S502
Y
F
L
Q
R
R
P
S
M
K
T
L
F
V
D
Site 43
T705
W
K
L
Q
R
A
I
T
I
L
D
T
E
K
S
Site 44
S775
E
G
V
K
R
T
L
S
F
S
L
R
S
S
R
Site 45
S801
V
P
L
L
R
E
A
S
A
R
D
R
Q
S
A
Site 46
S807
A
S
A
R
D
R
Q
S
A
Q
P
E
E
V
Y
Site 47
Y814
S
A
Q
P
E
E
V
Y
L
R
Q
F
S
G
S
Site 48
S821
Y
L
R
Q
F
S
G
S
L
K
P
E
D
A
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation