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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRPV3
Full Name:
Transient receptor potential cation channel subfamily V member 3
Alias:
Transient receptor potential cation channel V, 3; Transient receptor potential cation channel, subfamily V, member 3; Vanilloid receptor 3; Vanilloid receptor-like 3; Vanilloid receptor-related osmotically activated channel; VRL3; VRL-3
Type:
Ion channel, cation
Mass (Da):
90636
Number AA:
790
UniProt ID:
Q8NET8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005262
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Transient receptor potential cation channel subfamily V member 3 pan-specific antibody AB-NN353-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN353-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
G
K
R
V
A
A
P
S
G
N
P
A
I
L
P
Site 2
T35
E
K
R
P
A
E
I
T
P
T
K
K
S
A
H
Site 3
T37
R
P
A
E
I
T
P
T
K
K
S
A
H
F
F
Site 4
S40
E
I
T
P
T
K
K
S
A
H
F
F
L
E
I
Site 5
T55
E
G
F
E
P
N
P
T
V
A
K
T
S
P
P
Site 6
T59
P
N
P
T
V
A
K
T
S
P
P
V
F
S
K
Site 7
S60
N
P
T
V
A
K
T
S
P
P
V
F
S
K
P
Site 8
S65
K
T
S
P
P
V
F
S
K
P
M
D
S
N
I
Site 9
S70
V
F
S
K
P
M
D
S
N
I
R
Q
C
I
S
Site 10
S85
G
N
C
D
D
M
D
S
P
Q
S
P
Q
D
D
Site 11
S88
D
D
M
D
S
P
Q
S
P
Q
D
D
V
T
E
Site 12
T94
Q
S
P
Q
D
D
V
T
E
T
P
S
N
P
N
Site 13
T96
P
Q
D
D
V
T
E
T
P
S
N
P
N
S
P
Site 14
S98
D
D
V
T
E
T
P
S
N
P
N
S
P
S
A
Site 15
S102
E
T
P
S
N
P
N
S
P
S
A
Q
L
A
K
Site 16
T163
D
F
L
M
H
K
L
T
A
S
D
T
G
K
T
Site 17
S165
L
M
H
K
L
T
A
S
D
T
G
K
T
C
L
Site 18
T167
H
K
L
T
A
S
D
T
G
K
T
C
L
M
K
Site 19
Y254
G
A
F
F
N
P
K
Y
Q
H
E
G
F
Y
F
Site 20
Y260
K
Y
Q
H
E
G
F
Y
F
G
E
T
P
L
A
Site 21
T287
L
L
M
E
H
E
Q
T
D
I
T
S
R
D
S
Site 22
T290
E
H
E
Q
T
D
I
T
S
R
D
S
R
G
N
Site 23
S294
T
D
I
T
S
R
D
S
R
G
N
N
I
L
H
Site 24
T312
T
V
A
E
D
F
K
T
Q
N
D
F
V
K
R
Site 25
Y321
N
D
F
V
K
R
M
Y
D
M
I
L
L
R
S
Site 26
T335
S
G
N
W
E
L
E
T
T
R
N
N
D
G
L
Site 27
T336
G
N
W
E
L
E
T
T
R
N
N
D
G
L
T
Site 28
T343
T
R
N
N
D
G
L
T
P
L
Q
L
A
A
K
Site 29
Y359
G
K
A
E
I
L
K
Y
I
L
S
R
E
I
K
Site 30
S362
E
I
L
K
Y
I
L
S
R
E
I
K
E
K
R
Site 31
S372
I
K
E
K
R
L
R
S
L
S
R
K
F
T
D
Site 32
S374
E
K
R
L
R
S
L
S
R
K
F
T
D
W
A
Site 33
T378
R
S
L
S
R
K
F
T
D
W
A
Y
G
P
V
Site 34
Y382
R
K
F
T
D
W
A
Y
G
P
V
S
S
S
L
Site 35
S386
D
W
A
Y
G
P
V
S
S
S
L
Y
D
L
T
Site 36
S387
W
A
Y
G
P
V
S
S
S
L
Y
D
L
T
N
Site 37
Y390
G
P
V
S
S
S
L
Y
D
L
T
N
V
D
T
Site 38
T393
S
S
S
L
Y
D
L
T
N
V
D
T
T
T
D
Site 39
T397
Y
D
L
T
N
V
D
T
T
T
D
N
S
V
L
Site 40
T399
L
T
N
V
D
T
T
T
D
N
S
V
L
E
I
Site 41
T407
D
N
S
V
L
E
I
T
V
Y
N
T
N
I
D
Site 42
Y409
S
V
L
E
I
T
V
Y
N
T
N
I
D
N
R
Site 43
T421
D
N
R
H
E
M
L
T
L
E
P
L
H
T
L
Site 44
T427
L
T
L
E
P
L
H
T
L
L
H
M
K
W
K
Site 45
Y460
I
T
L
T
L
V
S
Y
Y
R
P
R
E
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation