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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VPS37A
Full Name:
Vacuolar protein sorting-associated protein 37A
Alias:
ESCRT-I complex subunit VPS37A;Hepatocellular carcinoma-related protein 1
Type:
Mass (Da):
44314
Number AA:
397
UniProt ID:
Q8NEZ2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
F
P
L
T
K
S
A
S
S
S
A
A
G
S
P
Site 2
S13
P
L
T
K
S
A
S
S
S
A
A
G
S
P
G
Site 3
S14
L
T
K
S
A
S
S
S
A
A
G
S
P
G
G
Site 4
S24
G
S
P
G
G
L
T
S
L
Q
Q
Q
K
Q
R
Site 5
S35
Q
K
Q
R
L
I
E
S
L
R
N
S
H
S
S
Site 6
S39
L
I
E
S
L
R
N
S
H
S
S
I
A
E
I
Site 7
S41
E
S
L
R
N
S
H
S
S
I
A
E
I
Q
K
Site 8
S42
S
L
R
N
S
H
S
S
I
A
E
I
Q
K
D
Site 9
Y52
E
I
Q
K
D
V
E
Y
R
L
P
F
T
I
N
Site 10
S81
P
Q
E
K
P
V
I
S
V
Y
P
P
I
R
H
Site 11
Y83
E
K
P
V
I
S
V
Y
P
P
I
R
H
H
L
Site 12
S100
K
Q
G
V
Y
V
T
S
P
L
V
N
N
F
T
Site 13
S118
D
L
G
K
I
I
Q
S
L
L
D
E
F
W
K
Site 14
Y139
P
T
S
T
A
F
P
Y
L
Y
S
N
P
S
G
Site 15
Y141
S
T
A
F
P
Y
L
Y
S
N
P
S
G
M
S
Site 16
S142
T
A
F
P
Y
L
Y
S
N
P
S
G
M
S
P
Site 17
S145
P
Y
L
Y
S
N
P
S
G
M
S
P
Y
A
S
Site 18
S148
Y
S
N
P
S
G
M
S
P
Y
A
S
Q
G
F
Site 19
Y150
N
P
S
G
M
S
P
Y
A
S
Q
G
F
P
F
Site 20
S152
S
G
M
S
P
Y
A
S
Q
G
F
P
F
L
P
Site 21
Y161
G
F
P
F
L
P
P
Y
P
P
Q
E
A
N
R
Site 22
S169
P
P
Q
E
A
N
R
S
I
T
S
L
S
V
A
Site 23
T171
Q
E
A
N
R
S
I
T
S
L
S
V
A
D
T
Site 24
S172
E
A
N
R
S
I
T
S
L
S
V
A
D
T
V
Site 25
S174
N
R
S
I
T
S
L
S
V
A
D
T
V
S
S
Site 26
T178
T
S
L
S
V
A
D
T
V
S
S
S
T
T
S
Site 27
S180
L
S
V
A
D
T
V
S
S
S
T
T
S
H
T
Site 28
S181
S
V
A
D
T
V
S
S
S
T
T
S
H
T
T
Site 29
S182
V
A
D
T
V
S
S
S
T
T
S
H
T
T
A
Site 30
S185
T
V
S
S
S
T
T
S
H
T
T
A
K
P
A
Site 31
S212
P
I
P
T
V
D
A
S
I
P
T
S
Q
N
G
Site 32
S216
V
D
A
S
I
P
T
S
Q
N
G
F
G
Y
K
Site 33
Y222
T
S
Q
N
G
F
G
Y
K
M
P
D
V
P
D
Site 34
S235
P
D
A
F
P
E
L
S
E
L
S
V
S
Q
L
Site 35
S238
F
P
E
L
S
E
L
S
V
S
Q
L
T
D
M
Site 36
S240
E
L
S
E
L
S
V
S
Q
L
T
D
M
N
E
Site 37
S275
D
K
D
D
L
V
K
S
I
E
E
L
A
R
K
Site 38
S289
K
N
L
L
L
E
P
S
L
E
A
K
R
Q
T
Site 39
T296
S
L
E
A
K
R
Q
T
V
L
D
K
Y
E
L
Site 40
Y301
R
Q
T
V
L
D
K
Y
E
L
L
T
Q
M
K
Site 41
T305
L
D
K
Y
E
L
L
T
Q
M
K
S
T
F
E
Site 42
S309
E
L
L
T
Q
M
K
S
T
F
E
K
K
M
Q
Site 43
T310
L
L
T
Q
M
K
S
T
F
E
K
K
M
Q
R
Site 44
S322
M
Q
R
Q
H
E
L
S
E
S
C
S
A
S
A
Site 45
S324
R
Q
H
E
L
S
E
S
C
S
A
S
A
L
Q
Site 46
S326
H
E
L
S
E
S
C
S
A
S
A
L
Q
A
R
Site 47
S328
L
S
E
S
C
S
A
S
A
L
Q
A
R
L
K
Site 48
S364
M
E
I
D
D
F
L
S
S
F
M
E
K
R
T
Site 49
S365
E
I
D
D
F
L
S
S
F
M
E
K
R
T
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation