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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZIMP7
Full Name:
Zinc finger MIZ domain-containing protein 2
Alias:
DKFZp761I2123; KIAA1886; NET27; PIAS-like protein Zimp7; Zinc finger, MIZ-type containing 2; ZMIZ2
Type:
Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Mass (Da):
96537
Number AA:
920
UniProt ID:
Q8NF64
International Prot ID:
IPI00302607
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043596
Uniprot
OncoNet
Molecular Function:
GO:0030374
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045944
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
P
A
P
H
G
D
G
S
F
A
Y
E
S
V
P
Site 2
Y23
H
G
D
G
S
F
A
Y
E
S
V
P
W
Q
Q
Site 3
S25
D
G
S
F
A
Y
E
S
V
P
W
Q
Q
S
A
Site 4
S31
E
S
V
P
W
Q
Q
S
A
T
Q
P
A
G
S
Site 5
T33
V
P
W
Q
Q
S
A
T
Q
P
A
G
S
L
S
Site 6
S54
G
V
G
N
A
T
Q
S
Q
V
L
G
N
P
M
Site 7
S66
N
P
M
G
P
A
G
S
P
S
G
S
S
M
M
Site 8
S68
M
G
P
A
G
S
P
S
G
S
S
M
M
P
G
Site 9
S70
P
A
G
S
P
S
G
S
S
M
M
P
G
V
A
Site 10
S71
A
G
S
P
S
G
S
S
M
M
P
G
V
A
G
Site 11
T84
A
G
G
S
S
A
L
T
S
P
Q
C
L
G
Q
Site 12
S85
G
G
S
S
A
L
T
S
P
Q
C
L
G
Q
Q
Site 13
Y103
E
G
G
A
N
K
G
Y
V
Q
Q
G
V
Y
S
Site 14
Y109
G
Y
V
Q
Q
G
V
Y
S
R
G
G
Y
P
G
Site 15
S110
Y
V
Q
Q
G
V
Y
S
R
G
G
Y
P
G
A
Site 16
Y114
G
V
Y
S
R
G
G
Y
P
G
A
P
G
F
T
Site 17
T122
P
G
A
P
G
F
T
T
G
Y
A
G
G
P
G
Site 18
S135
P
G
G
L
G
L
P
S
H
A
A
R
P
S
T
Site 19
S141
P
S
H
A
A
R
P
S
T
D
F
T
Q
A
A
Site 20
T142
S
H
A
A
R
P
S
T
D
F
T
Q
A
A
A
Site 21
T145
A
R
P
S
T
D
F
T
Q
A
A
A
A
A
A
Site 22
S176
A
A
L
Q
E
K
Q
S
Q
E
L
S
Q
Y
G
Site 23
S180
E
K
Q
S
Q
E
L
S
Q
Y
G
A
M
G
A
Site 24
Y182
Q
S
Q
E
L
S
Q
Y
G
A
M
G
A
G
Q
Site 25
S190
G
A
M
G
A
G
Q
S
F
N
S
Q
F
L
Q
Site 26
S193
G
A
G
Q
S
F
N
S
Q
F
L
Q
H
G
G
Site 27
S205
H
G
G
P
R
G
P
S
V
P
A
G
M
N
P
Site 28
T238
P
T
R
A
A
G
M
T
P
L
Y
A
G
Q
R
Site 29
Y241
A
A
G
M
T
P
L
Y
A
G
Q
R
L
P
Q
Site 30
Y251
Q
R
L
P
Q
H
G
Y
P
G
P
P
Q
A
Q
Site 31
Y269
R
Q
G
V
K
R
T
Y
S
E
V
Y
P
G
Q
Site 32
S270
Q
G
V
K
R
T
Y
S
E
V
Y
P
G
Q
Q
Site 33
Y273
K
R
T
Y
S
E
V
Y
P
G
Q
Q
Y
L
Q
Site 34
Y278
E
V
Y
P
G
Q
Q
Y
L
Q
G
G
Q
Y
A
Site 35
S287
Q
G
G
Q
Y
A
P
S
T
A
Q
F
A
P
S
Site 36
T288
G
G
Q
Y
A
P
S
T
A
Q
F
A
P
S
P
Site 37
S294
S
T
A
Q
F
A
P
S
P
G
Q
P
P
A
P
Site 38
S302
P
G
Q
P
P
A
P
S
P
S
Y
P
G
H
R
Site 39
S304
Q
P
P
A
P
S
P
S
Y
P
G
H
R
L
P
Site 40
Y305
P
P
A
P
S
P
S
Y
P
G
H
R
L
P
L
Site 41
T317
L
P
L
Q
Q
G
M
T
Q
S
L
S
V
P
G
Site 42
S319
L
Q
Q
G
M
T
Q
S
L
S
V
P
G
P
T
Site 43
S321
Q
G
M
T
Q
S
L
S
V
P
G
P
T
G
L
Site 44
Y330
P
G
P
T
G
L
H
Y
K
P
T
E
Q
F
N
Site 45
T333
T
G
L
H
Y
K
P
T
E
Q
F
N
G
Q
G
Site 46
S342
Q
F
N
G
Q
G
A
S
F
N
G
G
S
V
S
Site 47
S347
G
A
S
F
N
G
G
S
V
S
Y
S
Q
P
G
Site 48
S349
S
F
N
G
G
S
V
S
Y
S
Q
P
G
L
S
Site 49
Y350
F
N
G
G
S
V
S
Y
S
Q
P
G
L
S
G
Site 50
S351
N
G
G
S
V
S
Y
S
Q
P
G
L
S
G
P
Site 51
S356
S
Y
S
Q
P
G
L
S
G
P
T
R
S
I
P
Site 52
S361
G
L
S
G
P
T
R
S
I
P
G
Y
P
S
S
Site 53
Y365
P
T
R
S
I
P
G
Y
P
S
S
P
L
P
G
Site 54
S367
R
S
I
P
G
Y
P
S
S
P
L
P
G
N
P
Site 55
S368
S
I
P
G
Y
P
S
S
P
L
P
G
N
P
T
Site 56
T375
S
P
L
P
G
N
P
T
P
P
M
T
P
S
S
Site 57
T379
G
N
P
T
P
P
M
T
P
S
S
S
V
P
Y
Site 58
S381
P
T
P
P
M
T
P
S
S
S
V
P
Y
M
S
Site 59
S382
T
P
P
M
T
P
S
S
S
V
P
Y
M
S
P
Site 60
S383
P
P
M
T
P
S
S
S
V
P
Y
M
S
P
N
Site 61
Y386
T
P
S
S
S
V
P
Y
M
S
P
N
Q
E
V
Site 62
S388
S
S
S
V
P
Y
M
S
P
N
Q
E
V
K
S
Site 63
S395
S
P
N
Q
E
V
K
S
P
F
L
P
D
L
K
Site 64
S407
D
L
K
P
N
L
N
S
L
H
S
S
P
S
G
Site 65
S410
P
N
L
N
S
L
H
S
S
P
S
G
S
G
P
Site 66
S411
N
L
N
S
L
H
S
S
P
S
G
S
G
P
C
Site 67
S413
N
S
L
H
S
S
P
S
G
S
G
P
C
D
E
Site 68
S415
L
H
S
S
P
S
G
S
G
P
C
D
E
L
R
Site 69
T424
P
C
D
E
L
R
L
T
F
P
V
R
D
G
V
Site 70
Y456
F
Q
L
R
D
S
V
Y
K
T
L
I
M
R
P
Site 71
T458
L
R
D
S
V
Y
K
T
L
I
M
R
P
D
L
Site 72
T497
S
V
N
A
T
P
L
T
I
E
R
G
D
N
K
Site 73
T505
I
E
R
G
D
N
K
T
S
H
K
P
L
Y
L
Site 74
S506
E
R
G
D
N
K
T
S
H
K
P
L
Y
L
K
Site 75
Y511
K
T
S
H
K
P
L
Y
L
K
H
V
C
Q
P
Site 76
S545
L
Q
L
V
H
R
P
S
V
R
S
V
L
Q
G
Site 77
S548
V
H
R
P
S
V
R
S
V
L
Q
G
L
L
K
Site 78
T566
L
P
A
E
H
C
I
T
K
I
K
R
N
F
S
Site 79
S573
T
K
I
K
R
N
F
S
S
G
T
I
P
G
T
Site 80
T576
K
R
N
F
S
S
G
T
I
P
G
T
P
G
P
Site 81
T580
S
S
G
T
I
P
G
T
P
G
P
N
G
E
D
Site 82
Y669
I
Y
I
Q
N
S
D
Y
E
E
I
T
I
D
P
Site 83
T677
E
E
I
T
I
D
P
T
C
S
W
K
P
V
P
Site 84
T705
P
A
L
K
R
C
R
T
V
S
P
A
H
V
L
Site 85
S737
F
A
P
L
Q
P
P
S
V
P
A
P
S
D
Y
Site 86
S742
P
P
S
V
P
A
P
S
D
Y
P
G
Q
G
S
Site 87
Y744
S
V
P
A
P
S
D
Y
P
G
Q
G
S
S
F
Site 88
S749
S
D
Y
P
G
Q
G
S
S
F
L
G
P
G
T
Site 89
S750
D
Y
P
G
Q
G
S
S
F
L
G
P
G
T
F
Site 90
T756
S
S
F
L
G
P
G
T
F
P
E
S
F
P
P
Site 91
S760
G
P
G
T
F
P
E
S
F
P
P
T
T
P
S
Site 92
T764
F
P
E
S
F
P
P
T
T
P
S
T
P
T
L
Site 93
T765
P
E
S
F
P
P
T
T
P
S
T
P
T
L
A
Site 94
S767
S
F
P
P
T
T
P
S
T
P
T
L
A
E
F
Site 95
T768
F
P
P
T
T
P
S
T
P
T
L
A
E
F
T
Site 96
T770
P
T
T
P
S
T
P
T
L
A
E
F
T
P
G
Site 97
T775
T
P
T
L
A
E
F
T
P
G
P
P
P
I
S
Site 98
S782
T
P
G
P
P
P
I
S
Y
Q
S
D
I
P
S
Site 99
Y783
P
G
P
P
P
I
S
Y
Q
S
D
I
P
S
S
Site 100
S785
P
P
P
I
S
Y
Q
S
D
I
P
S
S
L
L
Site 101
S789
S
Y
Q
S
D
I
P
S
S
L
L
T
S
E
K
Site 102
S790
Y
Q
S
D
I
P
S
S
L
L
T
S
E
K
S
Site 103
T793
D
I
P
S
S
L
L
T
S
E
K
S
T
A
C
Site 104
S797
S
L
L
T
S
E
K
S
T
A
C
L
P
S
Q
Site 105
T798
L
L
T
S
E
K
S
T
A
C
L
P
S
Q
M
Site 106
S803
K
S
T
A
C
L
P
S
Q
M
A
P
A
G
H
Site 107
T814
P
A
G
H
L
D
P
T
H
N
P
G
T
P
G
Site 108
T819
D
P
T
H
N
P
G
T
P
G
L
H
T
S
N
Site 109
S825
G
T
P
G
L
H
T
S
N
L
G
A
P
P
G
Site 110
S838
P
G
P
Q
L
H
H
S
N
P
P
P
A
S
R
Site 111
S844
H
S
N
P
P
P
A
S
R
Q
S
L
G
Q
A
Site 112
S847
P
P
P
A
S
R
Q
S
L
G
Q
A
S
L
G
Site 113
S852
R
Q
S
L
G
Q
A
S
L
G
P
T
G
E
L
Site 114
T856
G
Q
A
S
L
G
P
T
G
E
L
A
F
S
P
Site 115
S872
T
G
V
M
G
P
P
S
M
S
G
A
G
E
A
Site 116
T891
L
D
L
L
P
E
L
T
N
P
D
E
L
L
S
Site 117
S898
T
N
P
D
E
L
L
S
Y
L
G
P
P
D
L
Site 118
Y899
N
P
D
E
L
L
S
Y
L
G
P
P
D
L
P
Site 119
T907
L
G
P
P
D
L
P
T
N
N
N
D
D
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation