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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLAD1
Full Name:
FAD synthase
Alias:
EC 2.7.7.2; FAD pyrophosphorylase; FAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae); FADS; Flavin adenine dinucleotide synthetase; FMN adenylyltransferase; Molybdenum cofactor biosynthesis protein-like region; PP591; RP11-307C12.7
Type:
Transferase
Mass (Da):
65266
Number AA:
587
UniProt ID:
Q8NFF5
International Prot ID:
IPI00220299
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0044424
GO:0044444
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003919
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0006747
GO:0006777
GO:0006777
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
F
Q
R
Q
E
Q
R
S
R
L
S
R
I
W
L
Site 2
S20
Q
E
Q
R
S
R
L
S
R
I
W
L
E
K
T
Site 3
S34
T
R
V
F
L
E
G
S
T
R
T
P
A
L
P
Site 4
T53
W
L
L
Q
V
P
S
T
Q
D
P
L
F
P
G
Site 5
Y61
Q
D
P
L
F
P
G
Y
G
P
Q
C
P
V
D
Site 6
Y85
L
F
G
G
L
G
G
Y
W
R
A
L
Q
R
G
Site 7
T99
G
R
E
G
R
T
M
T
S
R
A
S
E
L
S
Site 8
S100
R
E
G
R
T
M
T
S
R
A
S
E
L
S
P
Site 9
S103
R
T
M
T
S
R
A
S
E
L
S
P
G
R
S
Site 10
S106
T
S
R
A
S
E
L
S
P
G
R
S
V
T
A
Site 11
T132
G
H
T
Q
D
T
N
T
F
F
L
C
R
T
L
Site 12
S141
F
L
C
R
T
L
R
S
L
G
V
Q
V
C
R
Site 13
S165
T
I
A
A
E
V
T
S
F
S
N
R
F
T
H
Site 14
T171
T
S
F
S
N
R
F
T
H
V
L
T
A
G
G
Site 15
T187
G
P
T
H
D
D
V
T
F
E
A
V
A
Q
A
Site 16
S221
G
E
G
W
E
K
L
S
L
V
P
S
S
A
R
Site 17
S225
E
K
L
S
L
V
P
S
S
A
R
L
H
Y
G
Site 18
S226
K
L
S
L
V
P
S
S
A
R
L
H
Y
G
T
Site 19
Y231
P
S
S
A
R
L
H
Y
G
T
D
P
C
T
G
Site 20
T233
S
A
R
L
H
Y
G
T
D
P
C
T
G
Q
P
Site 21
Y285
Q
F
H
S
K
E
L
Y
V
A
A
D
E
A
S
Site 22
S312
G
R
R
L
G
L
G
S
Y
P
D
W
G
S
N
Site 23
Y313
R
R
L
G
L
G
S
Y
P
D
W
G
S
N
Y
Site 24
Y320
Y
P
D
W
G
S
N
Y
Y
Q
V
K
L
T
L
Site 25
Y321
P
D
W
G
S
N
Y
Y
Q
V
K
L
T
L
D
Site 26
T326
N
Y
Y
Q
V
K
L
T
L
D
S
E
E
E
G
Site 27
S329
Q
V
K
L
T
L
D
S
E
E
E
G
P
L
E
Site 28
T343
E
E
C
L
A
Y
L
T
A
R
L
P
Q
G
S
Site 29
S350
T
A
R
L
P
Q
G
S
L
V
P
Y
M
P
N
Site 30
Y354
P
Q
G
S
L
V
P
Y
M
P
N
A
V
E
Q
Site 31
Y367
E
Q
A
S
E
A
V
Y
K
L
A
E
S
G
S
Site 32
S372
A
V
Y
K
L
A
E
S
G
S
S
L
G
K
K
Site 33
S375
K
L
A
E
S
G
S
S
L
G
K
K
V
A
G
Site 34
T452
L
E
Q
F
L
Q
D
T
I
K
R
Y
N
L
Q
Site 35
S466
Q
M
L
E
A
E
G
S
M
K
Q
A
L
G
E
Site 36
T491
V
L
M
G
T
R
R
T
D
P
Y
S
C
S
L
Site 37
Y494
G
T
R
R
T
D
P
Y
S
C
S
L
C
P
F
Site 38
S495
T
R
R
T
D
P
Y
S
C
S
L
C
P
F
S
Site 39
S497
R
T
D
P
Y
S
C
S
L
C
P
F
S
P
T
Site 40
S502
S
C
S
L
C
P
F
S
P
T
D
P
G
W
P
Site 41
T504
S
L
C
P
F
S
P
T
D
P
G
W
P
A
F
Site 42
Y522
N
P
L
L
D
W
T
Y
R
D
I
W
D
F
L
Site 43
Y544
C
I
L
Y
D
R
G
Y
T
S
L
G
S
R
E
Site 44
T545
I
L
Y
D
R
G
Y
T
S
L
G
S
R
E
N
Site 45
S546
L
Y
D
R
G
Y
T
S
L
G
S
R
E
N
T
Site 46
S549
R
G
Y
T
S
L
G
S
R
E
N
T
V
R
N
Site 47
T553
S
L
G
S
R
E
N
T
V
R
N
P
A
L
K
Site 48
S563
N
P
A
L
K
C
L
S
P
G
G
H
P
T
Y
Site 49
T569
L
S
P
G
G
H
P
T
Y
R
P
A
Y
L
L
Site 50
Y570
S
P
G
G
H
P
T
Y
R
P
A
Y
L
L
E
Site 51
Y574
H
P
T
Y
R
P
A
Y
L
L
E
N
E
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation