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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP43
Full Name:
Nucleoporin Nup43
Alias:
p42
Type:
Mass (Da):
42133
Number AA:
380
UniProt ID:
Q8NFH3
International Prot ID:
IPI00171664
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005635
GO:0005643
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006886
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
E
I
Y
A
K
F
V
S
Q
K
I
S
K
T
R
Site 2
S14
K
F
V
S
Q
K
I
S
K
T
R
W
R
P
L
Site 3
T16
V
S
Q
K
I
S
K
T
R
W
R
P
L
P
P
Site 4
S25
W
R
P
L
P
P
G
S
L
Q
T
A
E
T
F
Site 5
T31
G
S
L
Q
T
A
E
T
F
A
T
G
S
W
D
Site 6
T34
Q
T
A
E
T
F
A
T
G
S
W
D
N
E
E
Site 7
S36
A
E
T
F
A
T
G
S
W
D
N
E
E
N
Y
Site 8
Y43
S
W
D
N
E
E
N
Y
I
S
L
W
S
I
G
Site 9
S57
G
D
F
G
N
L
D
S
D
G
G
F
E
G
D
Site 10
T108
L
H
H
P
N
N
Q
T
L
S
V
N
Q
Q
W
Site 11
Y120
Q
Q
W
T
T
A
H
Y
H
T
G
P
G
S
P
Site 12
T122
W
T
T
A
H
Y
H
T
G
P
G
S
P
S
Y
Site 13
S126
H
Y
H
T
G
P
G
S
P
S
Y
S
S
A
P
Site 14
S128
H
T
G
P
G
S
P
S
Y
S
S
A
P
C
T
Site 15
Y129
T
G
P
G
S
P
S
Y
S
S
A
P
C
T
G
Site 16
S130
G
P
G
S
P
S
Y
S
S
A
P
C
T
G
V
Site 17
S131
P
G
S
P
S
Y
S
S
A
P
C
T
G
V
V
Site 18
T135
S
Y
S
S
A
P
C
T
G
V
V
C
N
N
P
Site 19
S173
T
I
D
N
A
D
S
S
T
L
H
A
V
T
F
Site 20
S208
R
Q
Q
G
N
E
P
S
Q
I
L
S
L
T
G
Site 21
S212
N
E
P
S
Q
I
L
S
L
T
G
D
R
V
P
Site 22
T214
P
S
Q
I
L
S
L
T
G
D
R
V
P
L
H
Site 23
S243
G
G
Q
D
G
M
L
S
I
W
D
V
R
Q
G
Site 24
T251
I
W
D
V
R
Q
G
T
M
P
V
S
L
L
K
Site 25
S255
R
Q
G
T
M
P
V
S
L
L
K
A
H
E
A
Site 26
T279
S
N
P
E
H
L
F
T
C
S
E
D
G
S
L
Site 27
S281
P
E
H
L
F
T
C
S
E
D
G
S
L
W
H
Site 28
S292
S
L
W
H
W
D
A
S
T
D
V
P
E
K
S
Site 29
T293
L
W
H
W
D
A
S
T
D
V
P
E
K
S
S
Site 30
S299
S
T
D
V
P
E
K
S
S
L
F
H
Q
G
G
Site 31
S300
T
D
V
P
E
K
S
S
L
F
H
Q
G
G
R
Site 32
S308
L
F
H
Q
G
G
R
S
S
T
F
L
S
H
S
Site 33
S309
F
H
Q
G
G
R
S
S
T
F
L
S
H
S
I
Site 34
T310
H
Q
G
G
R
S
S
T
F
L
S
H
S
I
S
Site 35
S313
G
R
S
S
T
F
L
S
H
S
I
S
N
Q
A
Site 36
S315
S
S
T
F
L
S
H
S
I
S
N
Q
A
N
V
Site 37
S317
T
F
L
S
H
S
I
S
N
Q
A
N
V
H
Q
Site 38
S325
N
Q
A
N
V
H
Q
S
V
I
S
S
W
L
S
Site 39
S329
V
H
Q
S
V
I
S
S
W
L
S
T
D
P
A
Site 40
S332
S
V
I
S
S
W
L
S
T
D
P
A
K
D
R
Site 41
T333
V
I
S
S
W
L
S
T
D
P
A
K
D
R
I
Site 42
S344
K
D
R
I
E
I
T
S
L
L
P
S
R
S
L
Site 43
S348
E
I
T
S
L
L
P
S
R
S
L
S
V
N
T
Site 44
S350
T
S
L
L
P
S
R
S
L
S
V
N
T
L
D
Site 45
Y373
G
T
D
A
E
A
I
Y
V
T
R
H
L
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation