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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPRC5A
Full Name:
Retinoic acid-induced protein 3
Alias:
G protein-coupled receptor, family C, group 5, member A; GPCR5A; G-protein coupled receptor family C group 5 member A; Hypothetical protein FLJ10899; Putative G protein-coupled receptor; RAI3; RAIG1; Retinoic acid induced 3
Type:
Receptor, GPCR
Mass (Da):
40251
Number AA:
357
UniProt ID:
Q8NFJ5
International Prot ID:
IPI00022624
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0031410
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0004872
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0007165
GO:0007166
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
R
N
G
L
K
S
K
Y
Y
R
L
C
D
K
A
Site 2
S59
L
V
C
K
V
Q
D
S
N
R
R
K
M
L
P
Site 3
T67
N
R
R
K
M
L
P
T
Q
F
L
F
L
L
G
Site 4
S166
R
T
N
V
N
V
F
S
E
L
S
A
P
R
R
Site 5
S169
V
N
V
F
S
E
L
S
A
P
R
R
N
E
D
Site 6
T243
F
D
R
R
W
D
D
T
I
L
S
S
A
L
A
Site 7
T269
S
P
E
F
W
L
L
T
K
Q
R
N
P
M
D
Site 8
Y277
K
Q
R
N
P
M
D
Y
P
V
E
D
A
F
C
Site 9
S292
K
P
Q
L
V
K
K
S
Y
G
V
E
N
R
A
Site 10
Y293
P
Q
L
V
K
K
S
Y
G
V
E
N
R
A
Y
Site 11
Y300
Y
G
V
E
N
R
A
Y
S
Q
E
E
I
T
Q
Site 12
S301
G
V
E
N
R
A
Y
S
Q
E
E
I
T
Q
G
Site 13
T306
A
Y
S
Q
E
E
I
T
Q
G
F
E
E
T
G
Site 14
T312
I
T
Q
G
F
E
E
T
G
D
T
L
Y
A
P
Site 15
T315
G
F
E
E
T
G
D
T
L
Y
A
P
Y
S
T
Site 16
Y317
E
E
T
G
D
T
L
Y
A
P
Y
S
T
H
F
Site 17
Y320
G
D
T
L
Y
A
P
Y
S
T
H
F
Q
L
Q
Site 18
S321
D
T
L
Y
A
P
Y
S
T
H
F
Q
L
Q
N
Site 19
T322
T
L
Y
A
P
Y
S
T
H
F
Q
L
Q
N
Q
Site 20
S336
Q
P
P
Q
K
E
F
S
I
P
R
A
H
A
W
Site 21
S345
P
R
A
H
A
W
P
S
P
Y
K
D
Y
E
V
Site 22
Y347
A
H
A
W
P
S
P
Y
K
D
Y
E
V
K
K
Site 23
Y350
W
P
S
P
Y
K
D
Y
E
V
K
K
E
G
S
Site 24
S357
Y
E
V
K
K
E
G
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation