PhosphoNET

           
Protein Info 
   
Short Name:  BHLHE22
Full Name:  Class E basic helix-loop-helix protein 22
Alias:  Class B basic helix-loop-helix protein 5;Trinucleotide repeat-containing gene 20 protein
Type: 
Mass (Da):  36997
Number AA:  381
UniProt ID:  Q8NFJ8
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S22DDLFLHKSLSASTSK
Site 2S24LFLHKSLSASTSKRL
Site 3S26LHKSLSASTSKRLEA
Site 4S28KSLSASTSKRLEAAF
Site 5S37RLEAAFRSTPPGMDL
Site 6T38LEAAFRSTPPGMDLS
Site 7S45TPPGMDLSLAPPPRE
Site 8S56PPRERPASSSSSPLG
Site 9S57PRERPASSSSSPLGC
Site 10S58RERPASSSSSPLGCF
Site 11S60RPASSSSSPLGCFEP
Site 12S87PGGGGGGSAGSGGGG
Site 13S90GGGGSAGSGGGGGGG
Site 14Y129GAALCLKYGESASRG
Site 15S132LCLKYGESASRGSVA
Site 16S137GESASRGSVAESSGG
Site 17S141SRGSVAESSGGEQSP
Site 18S142RGSVAESSGGEQSPD
Site 19S147ESSGGEQSPDDDSDG
Site 20S152EQSPDDDSDGRCELV
Site 21S170GVADPRASPGAGGGG
Site 22S208GGGGGGGSSSGSSGG
Site 23S209GGGGGGSSSGSSGGG
Site 24S210GGGGGSSSGSSGGGG
Site 25S212GGGSSSGSSGGGGGS
Site 26S213GGSSSGSSGGGGGSG
Site 27S219SSGGGGGSGSGSGGS
Site 28S221GGGGGSGSGSGGSSS
Site 29S223GGGSGSGSGGSSSSS
Site 30S226SGSGSGGSSSSSSSS
Site 31S227GSGSGGSSSSSSSSS
Site 32S228SGSGGSSSSSSSSSK
Site 33S229GSGGSSSSSSSSSKK
Site 34S230SGGSSSSSSSSSKKS
Site 35S231GGSSSSSSSSSKKSK
Site 36S232GSSSSSSSSSKKSKE
Site 37S233SSSSSSSSSKKSKEQ
Site 38S234SSSSSSSSKKSKEQK
Site 39S237SSSSSKKSKEQKALR
Site 40Y271ELRAVIPYAHSPSVR
Site 41S274AVIPYAHSPSVRKLS
Site 42S276IPYAHSPSVRKLSKI
Site 43S281SPSVRKLSKIATLLL
Site 44T285RKLSKIATLLLAKNY
Site 45Y309EMRRLVAYLNQGQAI
Site 46S317LNQGQAISAASLPSS
Site 47Y341LHPALGAYEQAAGYP
Site 48Y347AYEQAAGYPFSAGLP
Site 49S368EKCALFNSVSSSLCK
Site 50S372LFNSVSSSLCKQCTE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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