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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MDGA1
Full Name:
MAM domain-containing glycosylphosphatidylinositol anchor protein 1
Alias:
GPI and MAM protein;Glycosylphosphatidylinositol-MAM;MAM domain-containing protein 3
Type:
Mass (Da):
105790
Number AA:
955
UniProt ID:
Q8NFP4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
H
C
R
G
Q
G
V
Y
A
P
A
Q
A
Q
I
Site 2
S44
V
V
K
E
D
N
I
S
E
R
V
Y
T
I
R
Site 3
Y48
D
N
I
S
E
R
V
Y
T
I
R
E
G
D
T
Site 4
T49
N
I
S
E
R
V
Y
T
I
R
E
G
D
T
L
Site 5
T73
P
R
P
Q
V
R
W
T
K
T
A
G
S
A
S
Site 6
T75
P
Q
V
R
W
T
K
T
A
G
S
A
S
D
K
Site 7
S80
T
K
T
A
G
S
A
S
D
K
F
Q
E
T
S
Site 8
S87
S
D
K
F
Q
E
T
S
V
F
N
E
T
L
R
Site 9
T92
E
T
S
V
F
N
E
T
L
R
I
E
R
I
A
Site 10
Y106
A
R
T
Q
G
G
R
Y
Y
C
K
A
E
N
G
Site 11
Y107
R
T
Q
G
G
R
Y
Y
C
K
A
E
N
G
V
Site 12
Y128
S
I
R
V
D
V
Q
Y
L
D
E
P
M
L
T
Site 13
T135
Y
L
D
E
P
M
L
T
V
H
Q
T
V
S
D
Site 14
T139
P
M
L
T
V
H
Q
T
V
S
D
V
R
G
N
Site 15
S141
L
T
V
H
Q
T
V
S
D
V
R
G
N
F
Y
Site 16
Y148
S
D
V
R
G
N
F
Y
Q
E
K
T
V
F
L
Site 17
T158
K
T
V
F
L
R
C
T
V
N
S
N
P
P
A
Site 18
S173
R
F
I
W
K
R
G
S
D
T
L
S
H
S
Q
Site 19
T175
I
W
K
R
G
S
D
T
L
S
H
S
Q
D
N
Site 20
S177
K
R
G
S
D
T
L
S
H
S
Q
D
N
G
V
Site 21
S179
G
S
D
T
L
S
H
S
Q
D
N
G
V
D
I
Site 22
Y187
Q
D
N
G
V
D
I
Y
E
P
L
Y
T
Q
G
Site 23
Y191
V
D
I
Y
E
P
L
Y
T
Q
G
E
T
K
V
Site 24
T192
D
I
Y
E
P
L
Y
T
Q
G
E
T
K
V
L
Site 25
Y209
K
N
L
R
P
Q
D
Y
A
S
Y
T
C
Q
V
Site 26
S211
L
R
P
Q
D
Y
A
S
Y
T
C
Q
V
S
V
Site 27
Y212
R
P
Q
D
Y
A
S
Y
T
C
Q
V
S
V
R
Site 28
T213
P
Q
D
Y
A
S
Y
T
C
Q
V
S
V
R
N
Site 29
T230
G
I
P
D
K
A
I
T
F
R
L
T
N
T
T
Site 30
T234
K
A
I
T
F
R
L
T
N
T
T
A
P
P
A
Site 31
T237
T
F
R
L
T
N
T
T
A
P
P
A
L
K
L
Site 32
S276
P
L
P
Q
L
Q
W
S
H
G
P
G
P
L
P
Site 33
S297
G
G
T
L
S
I
P
S
V
Q
A
R
D
S
G
Site 34
S303
P
S
V
Q
A
R
D
S
G
Y
Y
N
C
T
A
Site 35
Y305
V
Q
A
R
D
S
G
Y
Y
N
C
T
A
T
N
Site 36
Y306
Q
A
R
D
S
G
Y
Y
N
C
T
A
T
N
N
Site 37
T321
V
G
N
P
A
K
K
T
V
N
L
L
V
R
S
Site 38
T333
V
R
S
M
K
N
A
T
F
Q
I
T
P
D
V
Site 39
T337
K
N
A
T
F
Q
I
T
P
D
V
I
K
E
S
Site 40
Y369
V
P
Q
E
K
V
T
Y
Q
W
F
K
N
G
K
Site 41
S381
N
G
K
P
A
R
M
S
K
R
L
L
V
T
R
Site 42
Y413
H
F
S
D
Y
G
T
Y
L
C
M
A
S
F
P
Site 43
T441
S
S
E
T
V
P
P
T
I
S
V
P
K
G
R
Site 44
S443
E
T
V
P
P
T
I
S
V
P
K
G
R
A
V
Site 45
T452
P
K
G
R
A
V
V
T
V
R
E
G
S
P
A
Site 46
S457
V
V
T
V
R
E
G
S
P
A
E
L
Q
C
E
Site 47
T494
S
G
L
P
L
E
E
T
P
D
G
K
L
R
L
Site 48
S505
K
L
R
L
E
R
V
S
R
D
M
S
G
T
Y
Site 49
S509
E
R
V
S
R
D
M
S
G
T
Y
R
C
Q
T
Site 50
T511
V
S
R
D
M
S
G
T
Y
R
C
Q
T
A
R
Site 51
Y512
S
R
D
M
S
G
T
Y
R
C
Q
T
A
R
Y
Site 52
S545
P
P
E
V
E
P
S
S
Q
D
V
R
Q
A
L
Site 53
S561
R
P
V
L
L
R
C
S
L
L
R
G
S
P
Q
Site 54
S566
R
C
S
L
L
R
G
S
P
Q
R
I
A
S
A
Site 55
S572
G
S
P
Q
R
I
A
S
A
V
W
R
F
K
G
Site 56
T606
E
L
R
L
D
A
V
T
R
D
S
S
G
S
Y
Site 57
S609
L
D
A
V
T
R
D
S
S
G
S
Y
E
C
S
Site 58
S610
D
A
V
T
R
D
S
S
G
S
Y
E
C
S
V
Site 59
S612
V
T
R
D
S
S
G
S
Y
E
C
S
V
S
N
Site 60
Y613
T
R
D
S
S
G
S
Y
E
C
S
V
S
N
D
Site 61
S616
S
S
G
S
Y
E
C
S
V
S
N
D
V
G
S
Site 62
S618
G
S
Y
E
C
S
V
S
N
D
V
G
S
A
A
Site 63
S636
Q
V
S
A
K
A
Y
S
P
E
F
Y
F
D
T
Site 64
Y640
K
A
Y
S
P
E
F
Y
F
D
T
P
N
P
T
Site 65
T643
S
P
E
F
Y
F
D
T
P
N
P
T
R
S
H
Site 66
S649
D
T
P
N
P
T
R
S
H
K
L
S
K
N
Y
Site 67
S653
P
T
R
S
H
K
L
S
K
N
Y
S
Y
V
L
Site 68
Y658
K
L
S
K
N
Y
S
Y
V
L
Q
W
T
Q
R
Site 69
S679
P
V
L
N
Y
R
L
S
I
R
Q
L
N
Q
H
Site 70
Y706
E
K
G
Q
L
L
E
Y
I
L
T
D
L
R
V
Site 71
T709
Q
L
L
E
Y
I
L
T
D
L
R
V
P
H
S
Site 72
S716
T
D
L
R
V
P
H
S
Y
E
V
R
L
T
P
Site 73
Y717
D
L
R
V
P
H
S
Y
E
V
R
L
T
P
Y
Site 74
T722
H
S
Y
E
V
R
L
T
P
Y
T
T
F
G
A
Site 75
Y724
Y
E
V
R
L
T
P
Y
T
T
F
G
A
G
D
Site 76
T725
E
V
R
L
T
P
Y
T
T
F
G
A
G
D
M
Site 77
Y739
M
A
S
R
I
I
H
Y
T
E
P
I
N
S
P
Site 78
T740
A
S
R
I
I
H
Y
T
E
P
I
N
S
P
N
Site 79
S745
H
Y
T
E
P
I
N
S
P
N
L
S
D
N
T
Site 80
S749
P
I
N
S
P
N
L
S
D
N
T
C
H
F
E
Site 81
T752
S
P
N
L
S
D
N
T
C
H
F
E
D
E
K
Site 82
T780
W
T
R
Q
N
A
L
T
Q
N
P
K
R
S
P
Site 83
S786
L
T
Q
N
P
K
R
S
P
N
T
G
P
P
T
Site 84
T789
N
P
K
R
S
P
N
T
G
P
P
T
D
I
S
Site 85
T793
S
P
N
T
G
P
P
T
D
I
S
G
T
P
E
Site 86
S796
T
G
P
P
T
D
I
S
G
T
P
E
G
Y
Y
Site 87
T798
P
P
T
D
I
S
G
T
P
E
G
Y
Y
M
F
Site 88
Y803
S
G
T
P
E
G
Y
Y
M
F
I
E
T
S
R
Site 89
S809
Y
Y
M
F
I
E
T
S
R
P
R
E
L
G
D
Site 90
S822
G
D
R
A
R
L
V
S
P
L
Y
N
A
S
A
Site 91
T862
R
N
K
G
A
L
D
T
H
A
W
S
L
S
G
Site 92
S866
A
L
D
T
H
A
W
S
L
S
G
N
K
G
N
Site 93
S883
Q
Q
A
H
V
P
I
S
P
S
G
P
F
Q
I
Site 94
Y900
E
G
V
R
G
P
G
Y
L
G
D
I
A
I
D
Site 95
T910
D
I
A
I
D
D
V
T
L
K
K
G
E
C
P
Site 96
T921
G
E
C
P
R
K
Q
T
D
P
N
K
V
V
V
Site 97
S939
S
G
A
P
C
Q
S
S
P
Q
L
W
G
P
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation