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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC148
Full Name:
Coiled-coil domain-containing protein 148
Alias:
Type:
Mass (Da):
71104
Number AA:
591
UniProt ID:
Q8NFR7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
N
E
M
R
N
I
K
Y
K
P
V
D
Y
Q
Q
Site 2
Y29
I
K
Y
K
P
V
D
Y
Q
Q
L
R
A
L
T
Site 3
T36
Y
Q
Q
L
R
A
L
T
E
A
K
K
L
A
S
Site 4
S43
T
E
A
K
K
L
A
S
A
S
A
K
L
K
I
Site 5
T56
K
I
R
K
A
M
L
T
S
K
L
S
K
E
Q
Site 6
S60
A
M
L
T
S
K
L
S
K
E
Q
T
L
I
K
Site 7
T64
S
K
L
S
K
E
Q
T
L
I
K
Q
H
K
Q
Site 8
Y77
K
Q
V
W
W
Q
E
Y
Q
R
L
N
E
V
R
Site 9
S89
E
V
R
C
K
M
E
S
E
I
K
S
L
L
N
Site 10
S93
K
M
E
S
E
I
K
S
L
L
N
E
E
N
I
Site 11
T121
E
L
S
E
Q
Q
C
T
Y
L
K
N
V
I
N
Site 12
Y122
L
S
E
Q
Q
C
T
Y
L
K
N
V
I
N
P
Site 13
Y139
Q
L
R
A
D
L
K
Y
R
Q
H
H
T
L
Q
Site 14
T144
L
K
Y
R
Q
H
H
T
L
Q
H
S
H
P
H
Site 15
T172
F
V
K
K
Q
L
K
T
V
F
E
R
L
R
L
Site 16
S189
Q
R
I
E
N
D
L
S
D
W
S
I
K
I
L
Site 17
S192
E
N
D
L
S
D
W
S
I
K
I
L
D
H
S
Site 18
S199
S
I
K
I
L
D
H
S
L
E
E
K
T
N
P
Site 19
T204
D
H
S
L
E
E
K
T
N
P
L
S
E
L
P
Site 20
S208
E
E
K
T
N
P
L
S
E
L
P
I
E
L
E
Site 21
S216
E
L
P
I
E
L
E
S
L
E
C
P
Y
P
D
Site 22
Y221
L
E
S
L
E
C
P
Y
P
D
L
K
S
S
I
Site 23
S226
C
P
Y
P
D
L
K
S
S
I
L
S
E
F
Y
Site 24
S227
P
Y
P
D
L
K
S
S
I
L
S
E
F
Y
K
Site 25
S230
D
L
K
S
S
I
L
S
E
F
Y
K
F
T
Q
Site 26
Y239
F
Y
K
F
T
Q
K
Y
Q
K
K
L
Q
D
F
Site 27
Y254
N
L
Q
L
E
D
I
Y
R
N
C
Q
L
S
E
Site 28
Y267
S
E
E
D
H
W
I
Y
Q
A
I
L
D
Q
Y
Site 29
Y274
Y
Q
A
I
L
D
Q
Y
P
G
D
L
F
G
R
Site 30
T283
G
D
L
F
G
R
R
T
L
Y
L
D
M
L
Q
Site 31
Y285
L
F
G
R
R
T
L
Y
L
D
M
L
Q
R
Y
Site 32
Y292
Y
L
D
M
L
Q
R
Y
F
P
H
K
S
R
H
Site 33
Y307
D
L
V
E
H
E
K
Y
C
D
Q
Y
R
F
A
Site 34
Y311
H
E
K
Y
C
D
Q
Y
R
F
A
I
E
Q
Q
Site 35
T341
Q
K
A
V
L
T
L
T
E
A
C
A
T
H
E
Site 36
T346
T
L
T
E
A
C
A
T
H
E
M
E
S
M
L
Site 37
S389
A
R
L
E
M
E
I
S
A
R
R
R
E
K
E
Site 38
Y421
K
K
K
K
I
K
K
Y
W
A
K
K
K
Q
K
Site 39
S451
K
K
L
I
A
E
Q
S
L
K
D
R
E
R
V
Site 40
Y460
K
D
R
E
R
V
K
Y
R
Q
E
L
L
E
R
Site 41
S510
F
D
P
V
R
M
M
S
D
T
M
A
S
K
A
Site 42
T512
P
V
R
M
M
S
D
T
M
A
S
K
A
R
M
Site 43
S515
M
M
S
D
T
M
A
S
K
A
R
M
G
I
E
Site 44
T538
K
P
L
F
T
L
N
T
Y
N
E
Q
Q
I
I
Site 45
Y539
P
L
F
T
L
N
T
Y
N
E
Q
Q
I
I
S
Site 46
S546
Y
N
E
Q
Q
I
I
S
D
P
R
L
R
F
E
Site 47
Y566
A
G
L
H
R
T
L
Y
A
K
E
I
L
P
K
Site 48
S575
K
E
I
L
P
K
I
S
P
Q
K
P
P
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation