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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DBF4B
Full Name:
Protein DBF4 homolog B
Alias:
Activator of S phase kinase-like protein 1;Chiffon homolog B;Dbf4-related factor 1
Type:
Mass (Da):
67243
Number AA:
615
UniProt ID:
Q8NFT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
D
C
L
E
L
E
S
S
M
A
E
S
R
L
R
Site 2
S20
L
E
S
S
M
A
E
S
R
L
R
A
P
D
L
Site 3
S40
L
G
K
C
Q
K
N
S
P
G
A
R
K
H
P
Site 4
S49
G
A
R
K
H
P
F
S
G
K
S
F
Y
L
D
Site 5
S52
K
H
P
F
S
G
K
S
F
Y
L
D
L
P
A
Site 6
Y54
P
F
S
G
K
S
F
Y
L
D
L
P
A
G
K
Site 7
S86
G
F
L
S
K
E
V
S
Y
I
V
S
S
R
R
Site 8
S90
K
E
V
S
Y
I
V
S
S
R
R
E
V
K
A
Site 9
S91
E
V
S
Y
I
V
S
S
R
R
E
V
K
A
E
Site 10
S103
K
A
E
S
S
G
K
S
H
R
G
C
P
S
P
Site 11
S109
K
S
H
R
G
C
P
S
P
S
P
S
E
V
R
Site 12
S111
H
R
G
C
P
S
P
S
P
S
E
V
R
V
E
Site 13
S113
G
C
P
S
P
S
P
S
E
V
R
V
E
T
S
Site 14
T119
P
S
E
V
R
V
E
T
S
A
M
V
D
P
K
Site 15
S128
A
M
V
D
P
K
G
S
H
P
R
P
S
R
K
Site 16
S133
K
G
S
H
P
R
P
S
R
K
P
V
D
S
V
Site 17
S139
P
S
R
K
P
V
D
S
V
P
L
S
R
G
K
Site 18
S143
P
V
D
S
V
P
L
S
R
G
K
E
L
L
Q
Site 19
S158
K
A
I
R
N
Q
G
S
I
S
G
G
G
S
G
Site 20
S160
I
R
N
Q
G
S
I
S
G
G
G
S
G
G
S
Site 21
S164
G
S
I
S
G
G
G
S
G
G
S
S
S
L
L
Site 22
S167
S
G
G
G
S
G
G
S
S
S
L
L
T
N
A
Site 23
S168
G
G
G
S
G
G
S
S
S
L
L
T
N
A
R
Site 24
S169
G
G
S
G
G
S
S
S
L
L
T
N
A
R
S
Site 25
T172
G
G
S
S
S
L
L
T
N
A
R
S
W
G
V
Site 26
S198
V
Q
Q
L
S
L
A
S
L
C
V
K
K
Q
Q
Site 27
S218
G
T
C
P
A
A
E
S
R
T
R
K
V
A
R
Site 28
S249
P
F
H
H
Q
F
K
S
F
P
E
I
S
F
L
Site 29
S254
F
K
S
F
P
E
I
S
F
L
G
P
K
D
A
Site 30
S262
F
L
G
P
K
D
A
S
P
F
E
A
P
T
T
Site 31
T268
A
S
P
F
E
A
P
T
T
L
G
S
M
H
H
Site 32
T269
S
P
F
E
A
P
T
T
L
G
S
M
H
H
T
Site 33
S272
E
A
P
T
T
L
G
S
M
H
H
T
R
E
S
Site 34
T276
T
L
G
S
M
H
H
T
R
E
S
K
D
G
E
Site 35
S279
S
M
H
H
T
R
E
S
K
D
G
E
P
S
P
Site 36
S285
E
S
K
D
G
E
P
S
P
R
S
A
A
H
T
Site 37
S288
D
G
E
P
S
P
R
S
A
A
H
T
M
P
R
Site 38
T292
S
P
R
S
A
A
H
T
M
P
R
R
K
K
G
Site 39
Y300
M
P
R
R
K
K
G
Y
C
E
C
C
Q
E
A
Site 40
S322
L
Q
S
A
Q
H
R
S
F
A
L
E
A
H
L
Site 41
S357
Q
A
G
L
P
R
W
S
G
S
P
A
S
D
C
Site 42
S359
G
L
P
R
W
S
G
S
P
A
S
D
C
D
P
Site 43
S362
R
W
S
G
S
P
A
S
D
C
D
P
L
C
P
Site 44
T371
C
D
P
L
C
P
E
T
L
H
P
H
Q
P
S
Site 45
S378
T
L
H
P
H
Q
P
S
H
P
R
A
A
S
P
Site 46
S384
P
S
H
P
R
A
A
S
P
R
I
R
K
E
D
Site 47
S392
P
R
I
R
K
E
D
S
C
Q
A
S
V
T
Q
Site 48
S396
K
E
D
S
C
Q
A
S
V
T
Q
G
R
A
A
Site 49
T409
A
A
G
Q
Q
R
W
T
E
S
L
D
G
V
M
Site 50
S411
G
Q
Q
R
W
T
E
S
L
D
G
V
M
G
P
Site 51
S468
A
L
L
P
G
E
W
S
P
A
E
D
M
P
L
Site 52
S478
E
D
M
P
L
H
P
S
Q
E
N
S
F
A
P
Site 53
S482
L
H
P
S
Q
E
N
S
F
A
P
A
D
I
P
Site 54
T526
G
C
L
I
P
H
D
T
T
P
L
H
E
E
V
Site 55
T527
C
L
I
P
H
D
T
T
P
L
H
E
E
V
S
Site 56
S534
T
P
L
H
E
E
V
S
P
C
P
C
L
R
L
Site 57
S562
R
V
R
V
P
S
L
S
T
A
G
P
I
P
R
Site 58
T570
T
A
G
P
I
P
R
T
S
H
P
C
T
L
A
Site 59
T575
P
R
T
S
H
P
C
T
L
A
F
P
S
Y
L
Site 60
Y581
C
T
L
A
F
P
S
Y
L
N
D
H
D
L
G
Site 61
T600
A
K
P
Q
G
W
N
T
P
Q
P
F
L
H
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation