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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM58
Full Name:
Tripartite motif-containing protein 58
Alias:
BIA2; TRI58; Tripartite motif-containing 58
Type:
Uncharacterized protein
Mass (Da):
54766
Number AA:
486
UniProt ID:
Q8NG06
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
D
F
L
Q
E
P
V
S
V
D
C
G
H
S
F
Site 2
S47
I
S
E
F
C
E
K
S
D
G
A
Q
G
G
V
Site 3
Y55
D
G
A
Q
G
G
V
Y
A
C
P
Q
C
R
G
Site 4
S67
C
R
G
P
F
R
P
S
G
F
R
P
N
R
Q
Site 5
S104
A
R
H
G
E
D
L
S
R
F
C
E
E
D
E
Site 6
T126
D
A
G
P
E
H
R
T
H
R
T
A
P
L
Q
Site 7
S138
P
L
Q
E
A
A
G
S
Y
Q
V
K
L
Q
M
Site 8
T159
K
E
L
E
D
A
L
T
Q
E
A
N
V
G
K
Site 9
T211
L
E
A
E
E
R
A
T
L
Q
R
L
R
E
S
Site 10
S218
T
L
Q
R
L
R
E
S
K
S
R
L
V
Q
Q
Site 11
S220
Q
R
L
R
E
S
K
S
R
L
V
Q
Q
S
K
Site 12
S226
K
S
R
L
V
Q
Q
S
K
A
L
K
E
L
A
Site 13
S256
E
G
V
R
G
V
L
S
R
S
K
A
V
T
R
Site 14
S258
V
R
G
V
L
S
R
S
K
A
V
T
R
L
E
Site 15
T262
L
S
R
S
K
A
V
T
R
L
E
A
E
N
I
Site 16
S312
L
L
T
A
D
L
R
S
V
Q
D
G
E
P
W
Site 17
T331
N
N
P
E
R
F
D
T
W
P
C
I
L
G
L
Site 18
S340
P
C
I
L
G
L
Q
S
F
S
S
G
R
H
Y
Site 19
S342
I
L
G
L
Q
S
F
S
S
G
R
H
Y
W
E
Site 20
S343
L
G
L
Q
S
F
S
S
G
R
H
Y
W
E
V
Site 21
Y347
S
F
S
S
G
R
H
Y
W
E
V
L
V
G
E
Site 22
T366
G
L
G
V
C
Q
D
T
L
P
R
K
G
E
T
Site 23
T374
L
P
R
K
G
E
T
T
P
S
P
E
N
G
V
Site 24
S376
R
K
G
E
T
T
P
S
P
E
N
G
V
W
A
Site 25
Y392
W
L
L
K
G
N
E
Y
M
V
L
A
S
P
S
Site 26
S397
N
E
Y
M
V
L
A
S
P
S
V
P
L
L
Q
Site 27
S423
D
Y
E
A
G
E
I
S
F
Y
N
V
T
D
G
Site 28
Y425
E
A
G
E
I
S
F
Y
N
V
T
D
G
S
Y
Site 29
Y432
Y
N
V
T
D
G
S
Y
I
Y
T
F
N
Q
L
Site 30
Y434
V
T
D
G
S
Y
I
Y
T
F
N
Q
L
F
S
Site 31
T435
T
D
G
S
Y
I
Y
T
F
N
Q
L
F
S
G
Site 32
S471
A
G
S
G
N
W
A
S
R
D
H
L
D
P
A
Site 33
S479
R
D
H
L
D
P
A
S
D
V
R
D
D
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation