PhosphoNET

           
Protein Info 
   
Short Name:  ZNRF2
Full Name:  E3 ubiquitin-protein ligase ZNRF2
Alias:  E3 ubiquitin-protein ligase ZNRF2: Zinc/RING finger protein 2: RING finger protein 202: Protein Ells2: Ells2; EC 6.3.2.-; Protein Ells2; RING finger protein 202
Type:  Ubiquitin conjugating system, Ligase
Mass (Da):  24115
Number AA:  242
UniProt ID:  Q8NHG8
International Prot ID:  IPI00293427
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0005768  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0016874  GO:0005515  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0019941     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y18ANGRTRAYSGSDLPS
Site 2S19NGRTRAYSGSDLPSS
Site 3S21RTRAYSGSDLPSSSS
Site 4S25YSGSDLPSSSSGGAN
Site 5S26SGSDLPSSSSGGANG
Site 6S27GSDLPSSSSGGANGT
Site 7S28SDLPSSSSGGANGTA
Site 8S55RFPAQVPSAHQPSAS
Site 9S80AAPAAPRSRSLGGAV
Site 10S82PAAPRSRSLGGAVGS
Site 11S99SGARAAQSPFSIPNS
Site 12S102RAAQSPFSIPNSSSG
Site 13S106SPFSIPNSSSGPYGS
Site 14S107PFSIPNSSSGPYGSQ
Site 15S108FSIPNSSSGPYGSQD
Site 16Y111PNSSSGPYGSQDSVH
Site 17S113SSSGPYGSQDSVHSS
Site 18S116GPYGSQDSVHSSPED
Site 19S119GSQDSVHSSPEDGGG
Site 20S120SQDSVHSSPEDGGGG
Site 21S135RDRPVGGSPGGPRLV
Site 22S145GPRLVIGSLPAHLSP
Site 23S151GSLPAHLSPHMFGGF
Site 24S164GFKCPVCSKFVSSDE
Site 25S168PVCSKFVSSDEMDLH
Site 26T186CLTKPRITYNEDVLS
Site 27Y187LTKPRITYNEDVLSK
Site 28S193TYNEDVLSKDAGECA
Site 29T211EELQQGDTIARLPCL
Site 30S235EWFEVNRSCPEHPSD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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