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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLBL2
Full Name:
Putative phospholipase B-like 2
Alias:
EC 3.1.1.-; LAMA-like 2; Phospholipase B domain containing 2
Type:
Lysosomal lumen protein
Mass (Da):
65472
Number AA:
589
UniProt ID:
Q8NHP8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043202
Uniprot
OncoNet
Molecular Function:
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
GO:0016042
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
V
G
Q
M
Y
C
Y
P
G
S
H
L
A
R
Site 2
S59
D
G
Q
V
P
P
A
S
R
S
R
S
V
L
L
Site 3
S61
Q
V
P
P
A
S
R
S
R
S
V
L
L
D
V
Site 4
S63
P
P
A
S
R
S
R
S
V
L
L
D
V
S
A
Site 5
S106
A
F
L
E
L
G
T
S
G
Q
Y
N
D
S
L
Site 6
S112
T
S
G
Q
Y
N
D
S
L
Q
A
Y
A
A
G
Site 7
Y147
N
Y
C
G
P
F
E
Y
E
V
G
Y
C
E
R
Site 8
Y151
P
F
E
Y
E
V
G
Y
C
E
R
L
K
S
F
Site 9
S157
G
Y
C
E
R
L
K
S
F
L
E
A
N
L
E
Site 10
S176
E
M
E
S
N
P
D
S
P
Y
W
H
Q
V
R
Site 11
Y178
E
S
N
P
D
S
P
Y
W
H
Q
V
R
L
T
Site 12
S195
Q
L
K
G
L
E
D
S
Y
E
G
R
V
S
F
Site 13
Y196
L
K
G
L
E
D
S
Y
E
G
R
V
S
F
P
Site 14
S201
D
S
Y
E
G
R
V
S
F
P
A
G
K
F
T
Site 15
T233
L
E
L
A
L
N
K
T
K
I
K
P
S
L
G
Site 16
S238
N
K
T
K
I
K
P
S
L
G
S
G
S
C
S
Site 17
S241
K
I
K
P
S
L
G
S
G
S
C
S
A
L
I
Site 18
S243
K
P
S
L
G
S
G
S
C
S
A
L
I
K
L
Site 19
S255
I
K
L
L
P
G
Q
S
D
L
L
V
A
H
N
Site 20
Y267
A
H
N
T
W
N
N
Y
Q
H
M
L
R
V
I
Site 21
Y277
M
L
R
V
I
K
K
Y
W
L
Q
F
R
E
G
Site 22
Y289
R
E
G
P
W
G
D
Y
P
L
V
P
G
N
K
Site 23
T324
S
G
L
V
T
L
E
T
T
I
G
N
K
N
P
Site 24
Y336
K
N
P
A
L
W
K
Y
V
R
P
R
G
C
V
Site 25
T361
R
L
A
S
D
G
A
T
W
A
D
I
F
K
R
Site 26
S392
A
F
I
P
G
G
P
S
P
G
S
R
V
L
T
Site 27
S395
P
G
G
P
S
P
G
S
R
V
L
T
I
L
E
Site 28
T421
T
S
E
L
Y
Q
K
T
Y
W
A
S
Y
N
I
Site 29
Y422
S
E
L
Y
Q
K
T
Y
W
A
S
Y
N
I
P
Site 30
Y426
Q
K
T
Y
W
A
S
Y
N
I
P
S
F
E
T
Site 31
Y447
L
Q
A
L
V
A
Q
Y
G
D
W
F
S
Y
D
Site 32
S452
A
Q
Y
G
D
W
F
S
Y
D
G
S
P
R
A
Site 33
S456
D
W
F
S
Y
D
G
S
P
R
A
Q
I
F
R
Site 34
S467
Q
I
F
R
R
N
Q
S
L
V
Q
D
M
D
S
Site 35
S474
S
L
V
Q
D
M
D
S
M
V
R
L
M
R
Y
Site 36
Y481
S
M
V
R
L
M
R
Y
N
D
F
L
H
D
P
Site 37
S490
D
F
L
H
D
P
L
S
L
C
K
A
C
N
P
Site 38
S506
P
N
G
E
N
A
I
S
A
R
S
D
L
N
P
Site 39
Y518
L
N
P
A
N
G
S
Y
P
F
Q
A
L
R
Q
Site 40
S527
F
Q
A
L
R
Q
R
S
H
G
G
I
D
V
K
Site 41
S545
M
S
L
A
R
I
L
S
L
L
A
A
S
G
P
Site 42
S563
Q
V
P
P
F
Q
W
S
T
S
P
F
S
G
L
Site 43
S565
P
P
F
Q
W
S
T
S
P
F
S
G
L
L
H
Site 44
S568
Q
W
S
T
S
P
F
S
G
L
L
H
M
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation