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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEP70
Full Name:
Centrosomal protein of 70 kDa
Alias:
p10-binding protein
Type:
Mass (Da):
69752
Number AA:
597
UniProt ID:
Q8NHQ1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
A
P
K
P
Q
D
S
S
Q
P
S
D
R
L
Site 2
S12
A
P
K
P
Q
D
S
S
Q
P
S
D
R
L
M
Site 3
S15
P
Q
D
S
S
Q
P
S
D
R
L
M
T
E
K
Site 4
T20
Q
P
S
D
R
L
M
T
E
K
Q
Q
E
E
A
Site 5
S45
M
H
G
L
K
P
L
S
L
V
K
R
T
D
L
Site 6
S62
L
I
I
F
D
K
Q
S
S
Q
R
M
R
Q
N
Site 7
S63
I
I
F
D
K
Q
S
S
Q
R
M
R
Q
N
L
Site 8
T90
M
I
Q
E
L
I
E
T
N
Q
Q
L
R
N
E
Site 9
S124
Q
I
M
E
S
V
K
S
K
I
G
E
L
E
D
Site 10
S133
I
G
E
L
E
D
E
S
L
S
R
A
C
H
Q
Site 11
S135
E
L
E
D
E
S
L
S
R
A
C
H
Q
Q
N
Site 12
T153
D
L
Q
K
E
Q
K
T
L
Q
V
K
C
Q
H
Site 13
T171
K
R
T
E
Q
E
E
T
I
A
S
L
Q
M
E
Site 14
S174
E
Q
E
E
T
I
A
S
L
Q
M
E
V
C
R
Site 15
T192
E
E
E
D
R
I
V
T
Q
N
R
V
F
A
Y
Site 16
Y199
T
Q
N
R
V
F
A
Y
L
C
K
R
V
P
H
Site 17
Y219
Q
L
L
C
L
I
D
Y
Y
E
S
K
I
R
K
Site 18
T229
S
K
I
R
K
I
H
T
Q
R
Q
Y
K
E
D
Site 19
Y233
K
I
H
T
Q
R
Q
Y
K
E
D
E
S
Q
S
Site 20
S238
R
Q
Y
K
E
D
E
S
Q
S
E
E
E
N
D
Site 21
S240
Y
K
E
D
E
S
Q
S
E
E
E
N
D
Y
R
Site 22
Y246
Q
S
E
E
E
N
D
Y
R
N
L
D
A
S
P
Site 23
S252
D
Y
R
N
L
D
A
S
P
T
Y
K
G
L
L
Site 24
T254
R
N
L
D
A
S
P
T
Y
K
G
L
L
M
S
Site 25
S261
T
Y
K
G
L
L
M
S
L
Q
N
Q
L
K
E
Site 26
S271
N
Q
L
K
E
S
K
S
K
I
D
A
L
S
S
Site 27
S277
K
S
K
I
D
A
L
S
S
E
K
L
N
L
Q
Site 28
S278
S
K
I
D
A
L
S
S
E
K
L
N
L
Q
K
Site 29
T292
K
D
L
E
T
R
P
T
Q
H
E
L
R
L
Y
Site 30
Y299
T
Q
H
E
L
R
L
Y
K
Q
Q
V
K
K
L
Site 31
Y337
K
K
D
E
P
S
K
Y
N
Q
Q
Q
A
L
I
Site 32
Y369
P
R
A
P
V
I
I
Y
K
Q
T
K
G
G
V
Site 33
T404
E
M
W
A
D
Q
L
T
S
L
K
D
L
Y
K
Site 34
S405
M
W
A
D
Q
L
T
S
L
K
D
L
Y
K
S
Site 35
Y410
L
T
S
L
K
D
L
Y
K
S
L
K
T
L
S
Site 36
S412
S
L
K
D
L
Y
K
S
L
K
T
L
S
A
E
Site 37
T415
D
L
Y
K
S
L
K
T
L
S
A
E
L
V
P
Site 38
T465
S
N
M
P
H
F
Q
T
L
Q
A
I
V
S
H
Site 39
S471
Q
T
L
Q
A
I
V
S
H
F
Q
K
L
F
D
Site 40
S481
Q
K
L
F
D
V
P
S
L
N
G
V
Y
P
R
Site 41
Y486
V
P
S
L
N
G
V
Y
P
R
M
N
E
V
Y
Site 42
Y493
Y
P
R
M
N
E
V
Y
T
R
L
G
E
M
N
Site 43
S551
L
G
P
E
D
L
Q
S
I
I
Y
K
L
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation