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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RASSF8
Full Name:
Ras association domain-containing protein 8
Alias:
Carcinoma-associated protein HOJ-1; RASF8
Type:
Mass (Da):
48327
Number AA:
419
UniProt ID:
Q8NHQ8
International Prot ID:
Isoform1 - IPI00169294
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T41
I
G
R
T
G
R
Y
T
L
I
E
K
W
R
D
Site 2
T49
L
I
E
K
W
R
D
T
E
R
H
L
A
P
H
Site 3
Y69
S
L
N
K
W
G
Q
Y
A
S
D
V
Q
L
I
Site 4
S71
N
K
W
G
Q
Y
A
S
D
V
Q
L
I
L
R
Site 5
T80
V
Q
L
I
L
R
R
T
G
P
S
L
S
E
R
Site 6
S83
I
L
R
R
T
G
P
S
L
S
E
R
P
T
S
Site 7
S85
R
R
T
G
P
S
L
S
E
R
P
T
S
D
S
Site 8
T89
P
S
L
S
E
R
P
T
S
D
S
V
A
R
I
Site 9
S90
S
L
S
E
R
P
T
S
D
S
V
A
R
I
P
Site 10
S92
S
E
R
P
T
S
D
S
V
A
R
I
P
E
R
Site 11
T100
V
A
R
I
P
E
R
T
L
Y
R
Q
S
L
P
Site 12
Y102
R
I
P
E
R
T
L
Y
R
Q
S
L
P
P
L
Site 13
S105
E
R
T
L
Y
R
Q
S
L
P
P
L
A
K
L
Site 14
S119
L
R
P
Q
I
D
K
S
I
K
R
R
E
P
K
Site 15
S129
R
R
E
P
K
R
K
S
L
T
F
T
G
G
A
Site 16
T131
E
P
K
R
K
S
L
T
F
T
G
G
A
K
G
Site 17
T133
K
R
K
S
L
T
F
T
G
G
A
K
G
L
M
Site 18
T161
K
V
L
N
N
C
K
T
T
A
D
E
L
K
K
Site 19
T174
K
K
L
I
R
L
Q
T
E
K
L
Q
S
I
E
Site 20
S179
L
Q
T
E
K
L
Q
S
I
E
K
Q
L
E
S
Site 21
S186
S
I
E
K
Q
L
E
S
N
E
I
E
I
R
F
Site 22
Y198
I
R
F
W
E
Q
K
Y
N
S
N
L
E
E
E
Site 23
Y261
C
E
N
K
L
K
D
Y
L
A
Q
I
R
T
M
Site 24
S309
I
D
I
Q
G
Q
Q
S
L
R
L
E
N
G
I
Site 25
T361
Q
Q
T
G
T
K
V
T
V
L
P
A
E
P
I
Site 26
S373
E
P
I
E
I
E
A
S
H
A
D
I
E
R
E
Site 27
S385
E
R
E
A
P
F
Q
S
G
S
L
K
R
P
G
Site 28
S387
E
A
P
F
Q
S
G
S
L
K
R
P
G
S
S
Site 29
S393
G
S
L
K
R
P
G
S
S
R
Q
L
P
S
N
Site 30
S394
S
L
K
R
P
G
S
S
R
Q
L
P
S
N
L
Site 31
S399
G
S
S
R
Q
L
P
S
N
L
R
I
L
Q
N
Site 32
S409
R
I
L
Q
N
P
I
S
S
G
F
N
P
E
G
Site 33
Y418
G
F
N
P
E
G
I
Y
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation