PhosphoNET

           
Protein Info 
   
Short Name:  MFSD8
Full Name:  Major facilitator superfamily domain-containing protein 8
Alias:  Ceroid-lipofuscinosis neuronal protein 7; CLN7; major facilitator superfamily domain containing 8; MGC33302
Type: 
Mass (Da):  57609
Number AA:  518
UniProt ID:  Q8NHS3
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005764   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0008219  GO:0055085   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MAGLRNESEQEPLLG
Site 2T17QEPLLGDTPGSREWD
Site 3S34ETEEHYKSRWRSIRI
Site 4S38HYKSRWRSIRILYLT
Site 5S98SPIFGLWSNYRPRKE
Site 6Y100IFGLWSNYRPRKEPL
Site 7Y133IPASHNKYYMLVARG
Site 8Y134PASHNKYYMLVARGL
Site 9S161SYTAGATSLQERTSS
Site 10S167TSLQERTSSMANISM
Site 11S168SLQERTSSMANISMC
Site 12S240REHRVDDSGRQCKSI
Site 13S246DSGRQCKSINFEEAS
Site 14T254INFEEASTDEAQVPQ
Site 15Y298TPLTMDMYAWTQEQA
Site 16T377HNNSIPNTTFGEIII
Site 17S389IIIGLWKSPMEDDNE
Site 18T399EDDNERPTGCSIEQA
Site 19Y441NLMSYTLYSKILGPK
Site 20S510YKRLIALSVRYGRIQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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