KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MFSD8
Full Name:
Major facilitator superfamily domain-containing protein 8
Alias:
Ceroid-lipofuscinosis neuronal protein 7; CLN7; major facilitator superfamily domain containing 8; MGC33302
Type:
Mass (Da):
57609
Number AA:
518
UniProt ID:
Q8NHS3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005764
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
G
L
R
N
E
S
E
Q
E
P
L
L
G
Site 2
T17
Q
E
P
L
L
G
D
T
P
G
S
R
E
W
D
Site 3
S34
E
T
E
E
H
Y
K
S
R
W
R
S
I
R
I
Site 4
S38
H
Y
K
S
R
W
R
S
I
R
I
L
Y
L
T
Site 5
S98
S
P
I
F
G
L
W
S
N
Y
R
P
R
K
E
Site 6
Y100
I
F
G
L
W
S
N
Y
R
P
R
K
E
P
L
Site 7
Y133
I
P
A
S
H
N
K
Y
Y
M
L
V
A
R
G
Site 8
Y134
P
A
S
H
N
K
Y
Y
M
L
V
A
R
G
L
Site 9
S161
S
Y
T
A
G
A
T
S
L
Q
E
R
T
S
S
Site 10
S167
T
S
L
Q
E
R
T
S
S
M
A
N
I
S
M
Site 11
S168
S
L
Q
E
R
T
S
S
M
A
N
I
S
M
C
Site 12
S240
R
E
H
R
V
D
D
S
G
R
Q
C
K
S
I
Site 13
S246
D
S
G
R
Q
C
K
S
I
N
F
E
E
A
S
Site 14
T254
I
N
F
E
E
A
S
T
D
E
A
Q
V
P
Q
Site 15
Y298
T
P
L
T
M
D
M
Y
A
W
T
Q
E
Q
A
Site 16
T377
H
N
N
S
I
P
N
T
T
F
G
E
I
I
I
Site 17
S389
I
I
I
G
L
W
K
S
P
M
E
D
D
N
E
Site 18
T399
E
D
D
N
E
R
P
T
G
C
S
I
E
Q
A
Site 19
Y441
N
L
M
S
Y
T
L
Y
S
K
I
L
G
P
K
Site 20
S510
Y
K
R
L
I
A
L
S
V
R
Y
G
R
I
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation