KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GAS2L2
Full Name:
GAS2-like protein 2
Alias:
GA2L2; GAR17; GAS2-like 2; GAS2-related; GAS2-related protein on chromosome 17; growth arrest-specific 2 like 2; growth arrest-specific 2-like 2
Type:
Cytoskeletal protein
Mass (Da):
96520
Number AA:
880
UniProt ID:
Q8NHY3
International Prot ID:
IPI00169377
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
G
G
R
R
K
P
R
T
L
G
P
P
V
C
S
Site 2
S20
T
L
G
P
P
V
C
S
I
R
P
F
K
S
S
Site 3
S26
C
S
I
R
P
F
K
S
S
E
Q
Y
L
E
A
Site 4
S27
S
I
R
P
F
K
S
S
E
Q
Y
L
E
A
M
Site 5
Y30
P
F
K
S
S
E
Q
Y
L
E
A
M
K
E
D
Site 6
Y46
A
E
W
L
R
D
L
Y
G
L
D
I
D
A
A
Site 7
T107
N
G
A
A
Q
P
G
T
F
Q
A
R
D
N
V
Site 8
S191
A
L
P
P
P
D
P
S
P
P
A
P
P
R
R
Site 9
Y233
V
K
V
S
E
G
K
Y
R
V
G
D
S
N
T
Site 10
S238
G
K
Y
R
V
G
D
S
N
T
L
I
F
I
R
Site 11
T261
R
V
G
G
G
W
D
T
L
G
H
Y
L
D
K
Site 12
Y265
G
W
D
T
L
G
H
Y
L
D
K
H
D
P
C
Site 13
T275
K
H
D
P
C
R
C
T
S
L
S
H
K
P
G
Site 14
S276
H
D
P
C
R
C
T
S
L
S
H
K
P
G
S
Site 15
S278
P
C
R
C
T
S
L
S
H
K
P
G
S
F
L
Site 16
S283
S
L
S
H
K
P
G
S
F
L
K
P
P
A
P
Site 17
S303
V
R
V
Q
D
G
P
S
Q
T
Q
P
T
M
T
Site 18
T308
G
P
S
Q
T
Q
P
T
M
T
I
S
R
S
Q
Site 19
T310
S
Q
T
Q
P
T
M
T
I
S
R
S
Q
S
P
Site 20
S312
T
Q
P
T
M
T
I
S
R
S
Q
S
P
P
P
Site 21
S314
P
T
M
T
I
S
R
S
Q
S
P
P
P
P
V
Site 22
S316
M
T
I
S
R
S
Q
S
P
P
P
P
V
D
W
Site 23
T325
P
P
P
V
D
W
K
T
Y
T
S
S
D
R
R
Site 24
S328
V
D
W
K
T
Y
T
S
S
D
R
R
L
R
P
Site 25
S329
D
W
K
T
Y
T
S
S
D
R
R
L
R
P
P
Site 26
T337
D
R
R
L
R
P
P
T
P
S
S
P
R
P
R
Site 27
S339
R
L
R
P
P
T
P
S
S
P
R
P
R
R
E
Site 28
S340
L
R
P
P
T
P
S
S
P
R
P
R
R
E
R
Site 29
S354
R
G
A
G
T
G
A
S
R
E
M
A
P
F
L
Site 30
S367
F
L
R
C
Q
E
R
S
L
I
P
S
W
R
Q
Site 31
S371
Q
E
R
S
L
I
P
S
W
R
Q
P
T
A
G
Site 32
T376
I
P
S
W
R
Q
P
T
A
G
D
S
P
P
S
Site 33
S380
R
Q
P
T
A
G
D
S
P
P
S
P
Q
S
S
Site 34
S383
T
A
G
D
S
P
P
S
P
Q
S
S
S
T
Q
Site 35
S386
D
S
P
P
S
P
Q
S
S
S
T
Q
K
G
R
Site 36
S387
S
P
P
S
P
Q
S
S
S
T
Q
K
G
R
D
Site 37
S388
P
P
S
P
Q
S
S
S
T
Q
K
G
R
D
P
Site 38
T398
K
G
R
D
P
Q
C
T
S
S
G
K
R
E
E
Site 39
S400
R
D
P
Q
C
T
S
S
G
K
R
E
E
R
Y
Site 40
Y407
S
G
K
R
E
E
R
Y
P
P
E
L
P
R
G
Site 41
T418
L
P
R
G
R
I
P
T
S
W
V
H
E
E
T
Site 42
S419
P
R
G
R
I
P
T
S
W
V
H
E
E
T
D
Site 43
T436
G
T
D
A
G
N
P
T
P
Q
R
L
R
A
I
Site 44
T446
R
L
R
A
I
E
A
T
T
K
G
I
S
A
R
Site 45
S451
E
A
T
T
K
G
I
S
A
R
G
P
S
P
L
Site 46
S456
G
I
S
A
R
G
P
S
P
L
P
R
S
F
G
Site 47
S461
G
P
S
P
L
P
R
S
F
G
P
A
E
C
L
Site 48
S490
F
Q
F
R
E
P
E
S
V
R
S
P
T
P
V
Site 49
S493
R
E
P
E
S
V
R
S
P
T
P
V
Q
G
L
Site 50
T495
P
E
S
V
R
S
P
T
P
V
Q
G
L
T
K
Site 51
T501
P
T
P
V
Q
G
L
T
K
I
P
I
R
L
P
Site 52
T514
L
P
P
A
R
P
P
T
P
G
R
S
F
P
G
Site 53
S518
R
P
P
T
P
G
R
S
F
P
G
A
T
S
G
Site 54
S524
R
S
F
P
G
A
T
S
G
S
P
R
T
E
L
Site 55
S526
F
P
G
A
T
S
G
S
P
R
T
E
L
G
R
Site 56
S554
G
S
T
H
G
D
C
S
V
E
V
R
Q
E
D
Site 57
S575
V
M
A
E
A
R
E
S
W
D
L
G
L
Q
E
Site 58
T588
Q
E
Q
E
G
R
Y
T
P
L
P
L
G
G
N
Site 59
Y601
G
N
K
E
Q
A
I
Y
C
S
L
E
E
E
I
Site 60
S603
K
E
Q
A
I
Y
C
S
L
E
E
E
I
L
G
Site 61
S619
M
K
L
L
E
V
R
S
A
C
P
Q
G
T
R
Site 62
S627
A
C
P
Q
G
T
R
S
G
V
I
P
R
S
G
Site 63
S633
R
S
G
V
I
P
R
S
G
V
Y
I
P
R
L
Site 64
S662
I
Q
E
L
A
Q
G
S
P
S
L
L
K
V
D
Site 65
S664
E
L
A
Q
G
S
P
S
L
L
K
V
D
L
E
Site 66
T678
E
A
W
K
A
A
P
T
G
S
P
K
P
A
V
Site 67
S680
W
K
A
A
P
T
G
S
P
K
P
A
V
T
P
Site 68
T686
G
S
P
K
P
A
V
T
P
G
P
G
S
L
K
Site 69
S691
A
V
T
P
G
P
G
S
L
K
G
K
L
G
A
Site 70
S701
G
K
L
G
A
R
Q
S
G
P
R
T
K
A
S
Site 71
T705
A
R
Q
S
G
P
R
T
K
A
S
L
S
A
K
Site 72
S708
S
G
P
R
T
K
A
S
L
S
A
K
G
T
H
Site 73
S710
P
R
T
K
A
S
L
S
A
K
G
T
H
M
R
Site 74
T714
A
S
L
S
A
K
G
T
H
M
R
K
V
P
P
Site 75
S728
P
Q
G
G
Q
D
C
S
A
S
T
V
S
A
S
Site 76
S730
G
G
Q
D
C
S
A
S
T
V
S
A
S
P
E
Site 77
T731
G
Q
D
C
S
A
S
T
V
S
A
S
P
E
A
Site 78
S733
D
C
S
A
S
T
V
S
A
S
P
E
A
P
T
Site 79
S735
S
A
S
T
V
S
A
S
P
E
A
P
T
P
S
Site 80
T740
S
A
S
P
E
A
P
T
P
S
P
L
D
P
N
Site 81
S742
S
P
E
A
P
T
P
S
P
L
D
P
N
S
D
Site 82
S748
P
S
P
L
D
P
N
S
D
K
A
K
A
C
L
Site 83
S756
D
K
A
K
A
C
L
S
K
G
R
R
T
L
R
Site 84
T761
C
L
S
K
G
R
R
T
L
R
K
P
K
R
V
Site 85
S770
R
K
P
K
R
V
P
S
I
Y
K
L
K
L
R
Site 86
Y772
P
K
R
V
P
S
I
Y
K
L
K
L
R
P
R
Site 87
S793
H
R
P
E
K
Q
P
S
R
I
P
R
P
L
A
Site 88
Y801
R
I
P
R
P
L
A
Y
V
F
L
G
P
A
R
Site 89
S822
L
L
R
A
V
L
G
S
K
G
G
E
A
S
R
Site 90
S828
G
S
K
G
G
E
A
S
R
V
D
G
A
S
V
Site 91
S834
A
S
R
V
D
G
A
S
V
G
E
E
E
E
E
Site 92
S854
E
P
A
A
P
L
E
S
S
P
Q
P
P
E
G
Site 93
S855
P
A
A
P
L
E
S
S
P
Q
P
P
E
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation