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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VANGL1
Full Name:
Vang-like protein 1
Alias:
Loop-tail protein 2; LPP2; STB2; Strabismus 2; Van gogh; Van Gogh-like protein 1; VANG1; Vang-like 1
Type:
Adapter/scaffold protein
Mass (Da):
59975
Number AA:
524
UniProt ID:
Q8TAA9
International Prot ID:
IPI00031195
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
T
E
S
T
Y
S
G
Y
S
Y
Y
S
Site 2
S8
M
D
T
E
S
T
Y
S
G
Y
S
Y
Y
S
S
Site 3
Y10
T
E
S
T
Y
S
G
Y
S
Y
Y
S
S
H
S
Site 4
S11
E
S
T
Y
S
G
Y
S
Y
Y
S
S
H
S
K
Site 5
Y12
S
T
Y
S
G
Y
S
Y
Y
S
S
H
S
K
K
Site 6
Y13
T
Y
S
G
Y
S
Y
Y
S
S
H
S
K
K
S
Site 7
S14
Y
S
G
Y
S
Y
Y
S
S
H
S
K
K
S
H
Site 8
S15
S
G
Y
S
Y
Y
S
S
H
S
K
K
S
H
R
Site 9
S17
Y
S
Y
Y
S
S
H
S
K
K
S
H
R
Q
G
Site 10
S20
Y
S
S
H
S
K
K
S
H
R
Q
G
E
R
T
Site 11
T27
S
H
R
Q
G
E
R
T
R
E
R
H
K
S
P
Site 12
S33
R
T
R
E
R
H
K
S
P
R
N
K
D
G
R
Site 13
S42
R
N
K
D
G
R
G
S
E
K
S
V
T
I
Q
Site 14
S45
D
G
R
G
S
E
K
S
V
T
I
Q
P
P
T
Site 15
T47
R
G
S
E
K
S
V
T
I
Q
P
P
T
G
E
Site 16
T52
S
V
T
I
Q
P
P
T
G
E
P
L
L
G
N
Site 17
S61
E
P
L
L
G
N
D
S
T
R
T
E
E
V
Q
Site 18
T62
P
L
L
G
N
D
S
T
R
T
E
E
V
Q
D
Site 19
T80
G
E
T
T
T
A
I
T
G
T
S
E
H
S
I
Site 20
T82
T
T
T
A
I
T
G
T
S
E
H
S
I
S
Q
Site 21
S83
T
T
A
I
T
G
T
S
E
H
S
I
S
Q
E
Site 22
S86
I
T
G
T
S
E
H
S
I
S
Q
E
D
I
A
Site 23
S88
G
T
S
E
H
S
I
S
Q
E
D
I
A
R
I
Site 24
S96
Q
E
D
I
A
R
I
S
K
D
M
E
D
S
V
Site 25
S102
I
S
K
D
M
E
D
S
V
G
L
D
C
K
R
Site 26
S211
Y
G
V
R
I
L
D
S
R
D
R
N
Y
Q
G
Site 27
Y216
L
D
S
R
D
R
N
Y
Q
G
I
V
Q
Y
A
Site 28
T251
R
Q
L
Q
P
M
F
T
L
Q
V
V
R
S
T
Site 29
S257
F
T
L
Q
V
V
R
S
T
D
G
E
S
R
F
Site 30
T258
T
L
Q
V
V
R
S
T
D
G
E
S
R
F
Y
Site 31
S262
V
R
S
T
D
G
E
S
R
F
Y
S
L
G
H
Site 32
Y265
T
D
G
E
S
R
F
Y
S
L
G
H
L
S
I
Site 33
S266
D
G
E
S
R
F
Y
S
L
G
H
L
S
I
Q
Site 34
Y290
Y
Y
K
D
F
T
I
Y
N
P
N
L
L
T
A
Site 35
T296
I
Y
N
P
N
L
L
T
A
S
K
F
R
A
A
Site 36
Y312
H
M
A
G
L
K
V
Y
N
V
D
G
P
S
N
Site 37
S318
V
Y
N
V
D
G
P
S
N
N
A
T
G
Q
S
Site 38
T322
D
G
P
S
N
N
A
T
G
Q
S
R
A
M
I
Site 39
S338
A
A
A
R
R
R
D
S
S
H
N
E
L
Y
Y
Site 40
S339
A
A
R
R
R
D
S
S
H
N
E
L
Y
Y
E
Site 41
Y344
D
S
S
H
N
E
L
Y
Y
E
E
A
E
H
E
Site 42
Y345
S
S
H
N
E
L
Y
Y
E
E
A
E
H
E
R
Site 43
Y408
M
A
R
A
L
Q
K
Y
L
R
I
T
R
Q
Q
Site 44
T412
L
Q
K
Y
L
R
I
T
R
Q
Q
N
Y
H
S
Site 45
Y417
R
I
T
R
Q
Q
N
Y
H
S
M
E
S
I
L
Site 46
Y444
P
K
A
F
L
E
R
Y
L
S
A
G
P
T
L
Site 47
S446
A
F
L
E
R
Y
L
S
A
G
P
T
L
Q
Y
Site 48
T450
R
Y
L
S
A
G
P
T
L
Q
Y
D
K
D
R
Site 49
Y453
S
A
G
P
T
L
Q
Y
D
K
D
R
W
L
S
Site 50
T461
D
K
D
R
W
L
S
T
Q
W
R
L
V
S
D
Site 51
S467
S
T
Q
W
R
L
V
S
D
E
A
V
T
N
G
Site 52
S511
E
E
F
I
D
P
K
S
H
K
F
V
L
R
L
Site 53
S520
K
F
V
L
R
L
Q
S
E
T
S
V
_
_
_
Site 54
T522
V
L
R
L
Q
S
E
T
S
V
_
_
_
_
_
Site 55
S523
L
R
L
Q
S
E
T
S
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation