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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNIP1
Full Name:
Smad nuclear-interacting protein 1
Alias:
dJ423B22.2; FLJ12553; RP3-423B22.3; Smad nuclear interacting protein 1
Type:
Inhibitor protein
Mass (Da):
45778
Number AA:
396
UniProt ID:
Q8TAD8
International Prot ID:
IPI00154515
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0007154
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
K
A
V
K
S
E
R
E
R
G
S
R
Site 2
S12
K
S
E
R
E
R
G
S
R
R
R
H
R
D
G
Site 3
S35
V
V
K
Q
E
R
L
S
P
E
V
A
P
P
A
Site 4
S49
A
H
R
R
P
D
H
S
G
G
S
P
S
P
P
Site 5
S52
R
P
D
H
S
G
G
S
P
S
P
P
T
S
E
Site 6
S54
D
H
S
G
G
S
P
S
P
P
T
S
E
P
A
Site 7
T57
G
G
S
P
S
P
P
T
S
E
P
A
R
S
G
Site 8
S58
G
S
P
S
P
P
T
S
E
P
A
R
S
G
H
Site 9
S63
P
T
S
E
P
A
R
S
G
H
R
G
N
R
A
Site 10
S74
G
N
R
A
R
G
V
S
R
S
P
P
K
K
K
Site 11
S76
R
A
R
G
V
S
R
S
P
P
K
K
K
N
K
Site 12
S85
P
K
K
K
N
K
A
S
G
R
R
S
K
S
P
Site 13
S89
N
K
A
S
G
R
R
S
K
S
P
R
S
K
R
Site 14
S91
A
S
G
R
R
S
K
S
P
R
S
K
R
N
R
Site 15
S94
R
R
S
K
S
P
R
S
K
R
N
R
S
P
H
Site 16
S99
P
R
S
K
R
N
R
S
P
H
H
S
T
V
K
Site 17
S103
R
N
R
S
P
H
H
S
T
V
K
V
K
Q
E
Site 18
T104
N
R
S
P
H
H
S
T
V
K
V
K
Q
E
R
Site 19
S128
D
R
Q
H
R
E
P
S
E
Q
E
H
R
R
A
Site 20
S138
E
H
R
R
A
R
N
S
D
R
D
R
H
R
G
Site 21
S147
R
D
R
H
R
G
H
S
H
Q
R
R
T
S
N
Site 22
T152
G
H
S
H
Q
R
R
T
S
N
E
R
P
G
S
Site 23
S153
H
S
H
Q
R
R
T
S
N
E
R
P
G
S
G
Site 24
S159
T
S
N
E
R
P
G
S
G
Q
G
Q
G
R
D
Site 25
T169
G
Q
G
R
D
R
D
T
Q
N
L
Q
A
Q
E
Site 26
Y182
Q
E
E
E
R
E
F
Y
N
A
R
R
R
E
H
Site 27
S200
N
D
V
G
G
G
G
S
E
S
Q
E
L
V
P
Site 28
S202
V
G
G
G
G
S
E
S
Q
E
L
V
P
R
P
Site 29
S225
V
P
A
K
E
K
P
S
F
E
L
S
G
A
L
Site 30
S229
E
K
P
S
F
E
L
S
G
A
L
L
E
D
T
Site 31
T238
A
L
L
E
D
T
N
T
F
R
G
V
V
I
K
Site 32
Y246
F
R
G
V
V
I
K
Y
S
E
P
P
E
A
R
Site 33
S247
R
G
V
V
I
K
Y
S
E
P
P
E
A
R
I
Site 34
Y262
P
K
K
R
W
R
L
Y
P
F
K
N
D
E
V
Site 35
Y274
D
E
V
L
P
V
M
Y
I
H
R
Q
S
A
Y
Site 36
Y281
Y
I
H
R
Q
S
A
Y
L
L
G
R
H
R
R
Site 37
S298
D
I
P
I
D
H
P
S
C
S
K
Q
H
A
V
Site 38
Y313
F
Q
Y
R
L
V
E
Y
T
R
A
D
G
T
V
Site 39
T314
Q
Y
R
L
V
E
Y
T
R
A
D
G
T
V
G
Site 40
T319
E
Y
T
R
A
D
G
T
V
G
R
R
V
K
P
Site 41
Y327
V
G
R
R
V
K
P
Y
I
I
D
L
G
S
G
Site 42
T337
D
L
G
S
G
N
G
T
F
L
N
N
K
R
I
Site 43
Y349
K
R
I
E
P
Q
R
Y
Y
E
L
K
E
K
D
Site 44
Y350
R
I
E
P
Q
R
Y
Y
E
L
K
E
K
D
V
Site 45
Y367
F
G
F
S
S
R
E
Y
V
L
L
H
E
S
S
Site 46
S373
E
Y
V
L
L
H
E
S
S
D
T
S
E
I
D
Site 47
S374
Y
V
L
L
H
E
S
S
D
T
S
E
I
D
R
Site 48
T376
L
L
H
E
S
S
D
T
S
E
I
D
R
K
D
Site 49
S377
L
H
E
S
S
D
T
S
E
I
D
R
K
D
D
Site 50
S394
E
E
E
E
E
E
V
S
D
S
_
_
_
_
_
Site 51
S396
E
E
E
E
V
S
D
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation